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Re: Prozac side effects?---GREG

Posted by medlib on May 23, 2000, at 22:57:28

In reply to Wellbutrin withdrawals or Prozac side effects?, posted by Greg on May 23, 2000, at 13:50:05

> I was switched from Wellbutrin to Prozac last Friday at my docs suggestion. I had actually stopped the WB the prior Wednesday because I had been experiencing increasing irritability (not only short temper and anger, but physical irritability in the chest and stomach). I didn't have any withdrawals from the sudden stopage of the WB that I noticed. But the last few days I've had fatigue and nausea (like sea or air sickness). Could this be delayed withdrawal from the WB, side effects from the Prozac, or maybe a combination of both?
>
> I'm leaving on vacation for a week tomorrow and this is not the foot I want to start off on. Any thoughts?
>
> Tx,
> Greg
------------------------------

Greg--

Your SEs are most likely caused by Prozac. Wellbutrin has a short half-life; so, if no SE's appeared by Day 2 or 3 off W., they wouldn't suddenly appear on Day 5.

Prozac, as I think I mentioned earlier, has a *very* long half-life (it reaches peak concentration in 6-8 hrs., but is only half-gone in 1-3 days for new users, 4-16 days after longer-term use.). I'm guessing that you were prescribed 20mg caps. If you don't have time to get 10 mg. ones before you leave, take with you what relieves nausea best for you. And--

--take the Prozac in the evening, so that peak concentration (and greatest SEs) will occur while you are asleep.
--take it only every second or third evening (depending on how disabling SEs are.) You'll have plenty still left in your system on the "day/s off."
--Make breakfast on the morning after a Prozac evening dose low in fat (to avoid exacerbating nausea) and add extra caffeine to combat fatigue.

Finally, and most important, forget psych meds and have a great time! Nature has a way of reminding us to celebrate just being alive.

Well wishes----medlib



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