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Re: wellbutrin

Posted by Andre Allard on May 14, 2000, at 1:39:06

In reply to Re: wellbutrin, posted by Cam W. on May 14, 2000, at 0:50:42

Hey Samantha, just ignore us. Cam, a panel of 11 experts were convened for a conference to discuss wellbutrin's mechanism of antidepressant activity. They concluded that wellbutrin's mechanism of action appears to have an unusual, not fully understood, noradrenergic link. The wellbutrin metabolite hydroxybupropion probably plays a critical role in the antidepressant activity, which appears to be predominantly associated with long term noradrenergic effects. The mild central nervous system activating effects of wellbutrin appear to be due to weak dopaminergic mechanisms. There is some evidence that dopamine may contribute to wellbutrin's antidepressant properties. Antidepressant effects of wellbutrin are not serotonergically mediated. I am glad to hear that wellbutrin (no matter what it's mechanism is) is working for you.


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poster:Andre Allard thread:33345
URL: http://www.dr-bob.org/babble/20000508/msgs/33408.html