Posted by Cam W. on April 30, 2000, at 22:11:42
In reply to Re: Short Trial Success / Back to Cam, posted by Mark H. on April 30, 2000, at 15:26:41
Mark - I don't know why certain people decompensate quickly on TCAs. Could it be that the panic that gets worse for the first couple of weeks is kicking in hard? Perhaps another breakdown or anomoly of the HPA axis (or interrelated system) is at work.As for breakthrough depression following an initial hypomania when missing doses, this could mean that the blood level of your AD has dipped below the minimum effective concentration needed to adquately boost the biochemical entity (be it neurotransmitter or some undiscovered enzyme/protein) that is quelling the symptoms of your depression. This isn't usually seen unless the AD you are taking has a relatively short half-life (usually 24h or less).
Also, pharmacists, even me, do make mistakes. If a pharmacist says that they have never made a mistake, it is either their first day or they are lying. When in doubt, always ask!
As for the trigger for your hypomanic episodes, it can be something innocuous that you do at those times of year. Something even an simple as the excitement of cutting the grass for the first time that year (yea,right - sarcasm).
I hope you stay well and look forward to your insights on our conditions. Thanks for helping me on my quest for the Holy Grail (..er, knowledge). - Cam W.
poster:Cam W.
thread:31659
URL: http://www.dr-bob.org/babble/20000429/msgs/31799.html