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Re:to liz - serotonin and dopamine - musings

Posted by liz on April 12, 2000, at 9:50:06

In reply to Re:to liz - serotonin and dopamine - musings, posted by Cam W. on April 11, 2000, at 23:19:39

Cam, when you muse like this my eyes start to cross. I certainly don't have your science background and couldn't get it if I tried. I sort of preferred the little drawing on the TV screen, where they drew on a schematic a red line that went straight from the hypothalamus to the crotch. Now that I could understand! Sometimes ya gotta just take this stuff as an act of faith, lay back and enjoy the results! (I hope you can tell that my inflection is entirely teasing :-O ) Liz


liz - Sorry, I don't know the drug; and sexual function involves so many different receptors. Scientists are still fighting over what causes SSRI-induced delayed orgasms. I can't seem to get a straight answer anywhere, the deeper I look into the subject.
>
> A hypothesis - An increase in circulating dopamine may decrease serotonin levels, as the two interact opposingly. Decreased serotonin would lead to decreased serotonin-2A receptor stimulation (if indeed that is what is causing SSRI-induced sexual problems), thus resolving the delayed orgasm. The downside is what is the decrease in serotonin doing to the depression? Maybe nothing, as when we deplete someone of serotonin, they do not get depression. Decreased levels of serotonin are just a symptom of depression and these symptoms can be resolved by increasing serotonin. I don't know.
>
> Thinking out loud - Cam W.


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