Posted by Scott L. Schofield on January 16, 2000, at 20:51:17
In reply to Re: Addiction to Dexedrine, posted by saint james on December 6, 1999, at 20:28:34
> > saint james, you said,"The best and most common, tried and true cocktail for adult ADD is stim + AD." Are you sure of that? I know where you're coming from: Anxiety and dysthymia are frequenly coexist in adults with ADD and so these meds are often given. Yet I haven't read any studies saying that this combination (AD + stim) is "the rule" in adult ADD (excepting individual physicians' own preferences, eg, J Beiderman).
> > I'm curious, does Effexor interact with amphetamine as the tricyclics do, ie, does it increase amphetamine levels in the brain? SSRIs -- probably the most common ADs -- don't have this effect.
> On the adult ADD lists most are on AD + stim. Depression is often comorbid in ADD. Even if it is not many ADD'ers find AD reduce brain clutter.
> I can't speak for SSRI's and stims, SSRI's are of no use in me because I am an nor-e person. The TCA's and Effexor do increase effectiveness and levels of stims and vice versa. I have to account for this fact when choosing doses of each. (Effexor and Dexadrine) However in general most of the psyco meds will increase levels and sometimes effectivness. This is one reason why polydrug treatment works.
About 15 years or so ago, I knew of someone (adult) for whom imipramine (Trofranil) monotherapy seemed effective. I have come across a few posts suggesting that bupropion (Wellbutrin) can also be effective.
What are the current thoughts regarding these two drugs and their use in drug combinations?
poster:Scott L. Schofield