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Re: Adam - counteracting MAOI sexual dysfunction

Posted by Adam on November 20, 1999, at 0:49:54

In reply to Adam - counteracting MAOI sexual dysfunction, posted by Michael on November 19, 1999, at 23:18:23


I'm sorry, I can't help you with that one. I currently am taking selegiline,
and have experienced no sexual side effects from it; or if there are side effects,
they have caused somewhat enhanced functioning rather than dysfunction. So I
haven't needed to try any antidotes. My knowledge is fairly limited in this
stuff, and I don't know if I could suggest anything more than what you have.
One suggestion that I hesitate to make (given my own issues with an anxiety
disorder) might be to try switching to selegiline, and to augment that with
pindolol, as you have been doing with Marplan. Selegiline is a non-hydrazine
MAOI, and is quite activating, which might make it a less-than optimal choice
for anxiety. However, I have read coments on this board indicating selegiline
helped some with social phobia.

I'm sorry I couldn't be of more help. I know how frustrating your problem is
from personal experience (with SSRIs). The only solution I found, despite
trying a couple antidotes myself, was to change medications or put up with it.
I hope you find a better solution. Best of luck to you, and please let us know
if you find something that works.

> adam, i noticed you referred to MAOI's in your previous thread. have you any successful experience in counteracting MAOI induced sexual dysfunction (primarily anorgasmia or significantly delayed ejaculation)? i'm currently taking Marplan 80 mg/day, along with pindolol 15 mg/day (5 mg tid). This is very effective for my social phobia. I understand certain dopaminergic agonists (such as pergolide) have been used to reverse the sexual problems, as has Bupropion (even though it is contraindicated).
> Any help greatly appreciated.
> Michael




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