Posted by Judy on July 5, 1999, at 9:34:29
In reply to Re: Answers to Judy's Selegiline ?'s, posted by Elizabeth on July 4, 1999, at 23:08:01
I'm not sure I understand why the MAOI bypassing the GI tract avoids the tyramine problem. The MAOI is still very much in your system. Does it actually have to interact with the tyramine *in* the GI tract to cause trouble?
Elizabeth, please take this with the humor I intend it: If I read once more about your not having sex problems with all these different meds, I'm may freak and track you down and slap you silly out of my envy and frustration!!!! (Did I read in one of your posts that you're in the Boston area? I'm on the South Shore - about 20 miles south, so I might just be able to find you!) How the heck to you pull that off?!?!?! Of course, with all the other side effects you're suffering, it's probably not the magical experience for you that I'm imagining.
Thanks for the further info on Selegiline. Gives me something to think about for the future. In the meantime, I'll post my experience with Marplan as soon as I "feel" anything - good or bad.
Judy
--------------------------> > The selegiline patch is only available in research studies right now. Using a 30mg selegiline transdermal patch, the MAOI diet is not necessary.
>
> This is true; when the MAOI bypasses the GI tract, you don't have to worry about interactions with food. You *do*, however, still need to avoid drugs that can interact with MAOIs.
>
> I've taken selegiline in pills, up to I think 40mg. It caused some pretty bad insomnia and anxiety, and didn't seem to help much with the mood thing. My appetite actually got worse. No sex problems, but then I don't seem to get those.
>
> At high (20mg+, I believe) doses, you do need to observe the diet if taking it orally because it is no longer a selective inhibitor of MAO-B - at these doses it inhibits MAO-A irreversibly as well.
>
> You ladies will have to tell us all how the Marplan thing goes. I'm still having concentration problems, and I'd really much rather be able to take just an antidepressant and skip the lithium, as I'm getting an unpleasant side effect from it. (Acne! And here I thought that my skin had finally cleared up!)
poster:Judy
thread:5905
URL: http://www.dr-bob.org/babble/19991001/msgs/8290.html