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Re: Answers to Judy's Selegiline ?'s

Posted by Elizabeth on July 4, 1999, at 23:08:01

In reply to Re: Answers to Judy's Selegiline ?'s, posted by Annie on July 3, 1999, at 21:54:00

> The selegiline patch is only available in research studies right now. Using a 30mg selegiline transdermal patch, the MAOI diet is not necessary.

This is true; when the MAOI bypasses the GI tract, you don't have to worry about interactions with food. You *do*, however, still need to avoid drugs that can interact with MAOIs.

I've taken selegiline in pills, up to I think 40mg. It caused some pretty bad insomnia and anxiety, and didn't seem to help much with the mood thing. My appetite actually got worse. No sex problems, but then I don't seem to get those.

At high (20mg+, I believe) doses, you do need to observe the diet if taking it orally because it is no longer a selective inhibitor of MAO-B - at these doses it inhibits MAO-A irreversibly as well.

You ladies will have to tell us all how the Marplan thing goes. I'm still having concentration problems, and I'd really much rather be able to take just an antidepressant and skip the lithium, as I'm getting an unpleasant side effect from it. (Acne! And here I thought that my skin had finally cleared up!)

 

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poster:Elizabeth thread:5905
URL: http://www.dr-bob.org/babble/19991001/msgs/8287.html