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Re: I've never heard of SAMe

Posted by JohnL on June 30, 1999, at 14:53:07

In reply to I've never heard of SAMe, posted by Leonora on June 30, 1999, at 10:24:26

> I got my copy of Newsweek yesterday, and it touted a supplement called SAMe for depression. Anyone ever heard of it? Right now, after a disappointing trial and error with several SSRI's I seem to be maintaining with HTP5, but I was curious about this stuff.

Leonora (cool name), Nancy's right...SAMe is pricey, more expensive than prescription drugs, not covered by insurance either. Clinical research looks great, but my own trial of it seemed like I was taking nothing. No side effects, no benefits. I did better on 5HTP than anything, but had a bad side effect of burning genitals that was intolerable. If you've found something that works, you might want to ride it for all it's worth and not rock the boat. St. Johnswort goes very well with 5HTP in my experience, though adding it with caution in lower doses at first would be warranted. Both are a whole lot cheaper than SAMe. Best wishes for you. JohnL




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