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Re: paxil/celexa..is this as good as it gets?

Posted by Torrey on March 29, 1999, at 23:50:04

In reply to Re: paxil/celexa..is this as good as it gets?, posted by Wayne R. on March 29, 1999, at 8:16:32

Wayne R. wrote:
>I wonder if opiate interneurons in the RAS are the common system mediating the antidepressant effects of all the various meds we use.

Could you elaborate on this? I've been hearing about the use of low-dose opiates for treatment resistant OCD, and have wondered at the rationale behind it. Since the SSRI's arrived, the most prevalent idea about depression and anxiety disorders seems to be that "low serotonin" is the culprit. Bathing the neurons in reuptake-blocked serotonin does often seem to help - but inconsistently, and with a number of distressing side-effects. What is this RAS/opiate thing all about?

Torrey


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poster:Torrey thread:4142
URL: http://www.dr-bob.org/babble/19990401/msgs/4166.html