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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by med_empowered on October 21, 2007, at 22:25:29
i just ordered this stuff. taking 3grams a day, most days. I like it--A LOT. Anyone else have good experiences? Any bad experiences?
Posted by cumulative on October 22, 2007, at 0:25:10
In reply to hooray for niacinamide!, posted by med_empowered on October 21, 2007, at 22:25:29
My only comment is that, naturally, there's no reason whatsoever niacinamide wouldn't activate GABA tolerance/dependence, similar to benzodiazepines, so remember to titrate doses for a good long while if you're coming off. Glad you're doing well with it!
Posted by Jimmyboy on October 23, 2007, at 13:07:20
In reply to Re: hooray for niacinamide!, posted by cumulative on October 22, 2007, at 0:25:10
What is the difference in niacin (b3 - nicotinic acid) and niacinamide?
Thanks
JB
Posted by nolvas on October 23, 2007, at 19:19:47
In reply to Re: hooray for niacinamide!, posted by Jimmyboy on October 23, 2007, at 13:07:20
Niacinamide is the amide of Niacin (B3). Check here for details on what an amide is >
http://en.wikipedia.org/wiki/Amide
Niacinamide has different properties to Niacin so they are generally used to treat different conditions.
Posted by Maxime on October 24, 2007, at 20:23:34
In reply to hooray for niacinamide!, posted by med_empowered on October 21, 2007, at 22:25:29
> i just ordered this stuff. taking 3grams a day, most days. I like it--A LOT. Anyone else have good experiences? Any bad experiences?
I use it and it helps calm me down. I like it.
Maxime
Posted by Jimmyboy on October 27, 2007, at 12:00:56
In reply to Re: hooray for niacinamide! » med_empowered, posted by Maxime on October 24, 2007, at 20:23:34
How much do you guys take for anxiety, etc? Also how often. as in how many times per day?
And , if anyone knows, how are niacin aand niacinamide different? What are conditions do each help?Thanks for any info
JB
Posted by med_empowered on October 29, 2007, at 1:02:47
In reply to Re: hooray for niacinamide!, posted by Jimmyboy on October 27, 2007, at 12:00:56
I'm not an expert or anything, but...
Niacin and Niacinamide were/are both used in Orthomolecular treatment for schizophrenia. Niacinamide is apparently better tolerated (no flushing, fewer probs with elevated liver enzymes, etc.), and is used by Orthomolecular docs for schizophrenia and anxiety disorders.
Niacin lowers cholesterol; niacinamide does not.Dosages can vary wildly. For Niacinamide, treatment of psychosis usually requires 3 grams at least; anxiety, several hundred mgs to several grams...some protocols call for matching amounts of vitamin c plus other stuff (5-htp, for instance).
Personally, I take 3-5grams daily, 1gram @ a time. It helps a good bit; I do sometimes get sedated, and my friends sometimes notice that I sound "drugged" immediately after a dose, but these effects are pretty mild. All in all, I'd say for me niacinamide is a lot like a benzo, only the improvement has been less sudden and the sedation has been less pronounced (and I haven't really noticed any disinhibition, which is nice).
Nausea can be a problem, though, so do watch out for that.
Good luck!
Posted by daorlando on November 9, 2007, at 6:13:08
In reply to hooray for niacinamide!, posted by med_empowered on October 21, 2007, at 22:25:29
I had a bad experience with it. It didn't help my anxiety in any way, but it caused a headache, heartburn and transit hypoglycemia. Dose was 200 mg, form niacinamide. I can take up to 50mg in a multi though without those side effects.
Posted by psychobot5000 on November 15, 2007, at 18:01:28
In reply to hooray for niacinamide!, posted by med_empowered on October 21, 2007, at 22:25:29
> i just ordered this stuff. taking 3grams a day, most days. I like it--A LOT. Anyone else have good experiences? Any bad experiences?
>I used niacinamide 100-500mg for several weeks, and found it to be somewhat effective for anxiety and as a hypnotic (felt like a milder version of a benzodiazepine). However, after a couple of hours it would cause me to wake up, I believe.
I have read that niacinamide is metabolised into histamine - a transmitter that's involved in increasing alertness - within several hours after being taken. So, just be aware that, because of that, it may not be very good as a sleep remedy, unless you just need a brief nap. It might disrupt sleep if taken before going to bed, even though it feels good during the first hour.
I wouldn't really call it a bad experience, but it wasn't really that useful to me.
This is the end of the thread.
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