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Dr. Bob is Robert Hsiung, MD,
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Posted by Hugh on August 8, 2021, at 11:21:21
May 20, 2021
Individuals living with severe Alzheimer's disease showed remarkable improvements in behaviour and cognition within days of receiving an innovative new treatment that delivered low doses of radiation, a recent Baycrest-Sunnybrook pilot study found.
The study was a clinical follow-up to a 2015 case report about a patient in hospice with Alzheimer's disease. After being treated several times with radiation to her brain, she showed such significant improvements in cognition, speech, movement and appetite that she was discharged from the hospice to a long-term care home for older adults.
High doses of radiation are known to have harmful effects on our health. However, low doses, such as those used for diagnostic CT scans, can help the body protect and repair itself.
"Numerous neurological disorders, including Alzheimer's disease, are thought to be caused in part by oxidative stress that damages all cells, including those in the brain. We have natural protection systems to combat the damage, but they become less effective as we get older. Each dose of radiation stimulates our natural protection systems to work harder - to produce more antioxidants that prevent oxidative damage, to repair more DNA damage and to destroy more mutated cells," says Dr. Jerry Cuttler, a retired Atomic Energy of Canada scientist. He has been researching the effects of radiation on health for more than 25 years and is the lead author of the study.
In this study, published in the Journal of Alzheimer's Disease, four individuals living with severe Alzheimer's disease were given three treatments of low-dose radiation, each spaced two weeks apart. A CT scanner at Sunnybrook Health Sciences Centre was employed to provide the treatments, with the supervision and support of Dr. Sandra Black, senior scientist and neurologist, and Dr. Sean Symons, radiologist-in-chief, both at Sunnybrook. The researchers used standardized tests and observation to record changes in the patients' communication and behaviour after the treatment. Most importantly, they collected information (descriptions, photos and videos) from the patients' spouse, children and caregivers.
Remarkably, three of the four individuals showed improvements within one day of the first treatment, with their relatives reporting increased alertness and responsiveness, recognition of loved ones, mobility, social engagement, mood and more.
Two days after the first treatment, the son of one of the patients reported, "When I said hello, she looked at me and said, 'Hello dear.' She hadn't said this to me in years!"
The daughter of another patient noted: "I had an amazing visit with my dad this evening. I'm speechless from last night. He was excited to see me - he spoke to me right away and gave me multiple kisses - real kisses like years ago. He was clapping his hands to the music. My mom agreed it's been years since he has done this. Everyone is amazed."
Complete article:CTV video report:
Posted by Hugh on August 10, 2021, at 10:12:19
In reply to A surprising neurological treatment, posted by Hugh on August 8, 2021, at 11:21:21
The low dose of radiation (LDR) has received growing attention for its beneficial neuroprotective effect. This study was designed to investigate the enhancing effect of LDR on the antidepressant potential of resveratrol against diazepam-induced depression in mice. Female mice divided into five groups; control, diazepam (2 mg/kg), LDR (0.5Gy) + diazepam, resveratrol (20 mg/kg) + diazepam, LDR + resveratrol+diazepam. Mice received diazepam showed depressive symptoms as evidenced by decreased locomotor activity in the open field and increased immobility time in the forced swimming and tail suspension tests integrated with a marked decline in biogenic amines (serotonin, norepinephrine, and dopamine) in brain tissues. These effects were ameliorated by LDR or resveratrol administration demonstrating an antidepressant activity. Interestingly, LDR triggered the antidepressant effect of resveratrol as it restored the changes in behavioral tests, neurotransmitters, and neuro-histoarchitecture. In conclusion, these findings suggested that LDR could be considered as a novel adjuvant that augmented the resveratrol antidepressant effect and might serve as a potential therapeutic approach for depression.
Environ Toxicol 2020 Oct;35(10):1137-1145.
doi: 10.1002/tox.22949. Epub 2020 May 28.https://pubmed.ncbi.nlm.nih.gov/32463565/
Another low dose radiation study:
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