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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 21 of 21. This is the beginning of the thread.
Posted by Chinaboy on February 9, 2015, at 5:41:19
Hi,there! One of the provincialLy famous pdoc has given me the most accurate diagnosis so far, which is schizophrenia (mainly negative symptoms). And the
med combo he offered is Abilify 10mg, Olanzapine 10mg, Risperidal 2mg.So far so good. I can clearly feel that it is working, which is so unlike previously when I was on a ton of meds only to find none of them ever worked.
But can any of you guys help point out any synergic effects among these meds? (why they are put together?) Are there any problems with them? Is there anything I can add to them?
Do please tell me anything you know about them! I do want to learn from you guys! Thank you in advance!
Posted by Phillipa on February 9, 2015, at 8:48:28
In reply to Please take a look at this combo for schizophrenia, posted by Chinaboy on February 9, 2015, at 5:41:19
I just know that all three are atypical antipsychotics. How come three together? You mentioned tons of med before. What meds were you taking before? Phillipa
Posted by Louisiana Sportsman on February 9, 2015, at 11:00:12
In reply to Please take a look at this combo for schizophrenia, posted by Chinaboy on February 9, 2015, at 5:41:19
> Hi,there! One of the provincialLy famous pdoc has given me the most accurate diagnosis so far, which is schizophrenia (mainly negative symptoms). And the
> med combo he offered is Abilify 10mg, Olanzapine 10mg, Risperidal 2mg.
>
> So far so good. I can clearly feel that it is working, which is so unlike previously when I was on a ton of meds only to find none of them ever worked.
>
> But can any of you guys help point out any synergic effects among these meds? (why they are put together?) Are there any problems with them? Is there anything I can add to them?
>
> Do please tell me anything you know about them! I do want to learn from you guys! Thank you in advance!It is difficult to treat the negative symptoms of schizophrenia with psychotropic medication alone; I highly recommend that you ask your PDOC to refer to a therapist specializing in schizophrenia.
With that being said, I am skeptical of your med combo. The Risperdal (risperidone) 2mg. is useless with your other two antipsychotics.
I would stick with either the Abilify or olanazapine at maybe a higher dose and consider lamotrigine (Lamictal) since glutamate plays a role in treatment-resistant schizophrenia.
The only combo of antipsychotics I like is Abilify/Latuda combined with Seroquel (Quetiapine) if insomnia/depression/schizoaffective is present, but that is just me, and I am a fan of Lamictal if schizoaffective or treatment-resistant schizophrenia is present.
Good luck!
Posted by Lamdage22 on February 9, 2015, at 12:13:53
In reply to Re: Please take a look at this combo for schizophrenia, posted by Louisiana Sportsman on February 9, 2015, at 11:00:12
Stick with Abilify.
Olanzapine may cause (type 2) diabetes.
I am taking it myself because i know otherwise i would be a psychotic psycho to my family.
Posted by rjlockhart37 on February 9, 2015, at 14:18:43
In reply to Re: Please take a look at this combo for schizophrenia, posted by Lamdage22 on February 9, 2015, at 12:13:53
my recomendation is zyprexa, but yea lamdageis right diabeties risk....which i need to get a blood test done because somteims i crave sweets on zyprexa
it lasts a long time, so you don't have to redose.....
that or respiridal
Posted by Zyprexa on February 9, 2015, at 23:23:40
In reply to Please take a look at this combo for schizophrenia, posted by Chinaboy on February 9, 2015, at 5:41:19
I've taken all three, not at the same time. The risperdal and abilify did not help or made me worse. The zyprexa is the best med I've ever taken. Taken it for 17 years now and no diabeties. The abilify made me hypoglycemic. Had to constantly eat sugar just to keep my sugar high enough, so I wouldn't pass out, even though I didn't want to. Risperdal I was catatonic and holucinating all the time.
Posted by Lamdage22 on February 10, 2015, at 3:37:32
In reply to Re: Please take a look at this combo for schizophrenia, posted by Zyprexa on February 9, 2015, at 23:23:40
> Taken it for 17 years now and no diabeties.
That is encouraging.
If you tolerate it i would still recommend abilify because it usually doesnt shut you down as much as say, Zyprexa.
Posted by Christ_empowered on February 10, 2015, at 9:25:27
In reply to Re: Please take a look at this combo for schizophrenia, posted by Lamdage22 on February 10, 2015, at 3:37:32
I'd try to take just 1 AP/AAP, if you can. I take 30 Abilify, some other stuff, then 2mgs/Risperdal as needed for agitation. Works well for me.
Maybe ask about increasing the Abilify and drop everything else, except maybe something for as needed use? Abilify is easier to tolerate than many other options, so that's why I'd personally choose it over other AAP/AP drugs.
Posted by ed_uk2010 on February 10, 2015, at 12:22:07
In reply to Re: Please take a look at this combo for schizophrenia, posted by Christ_empowered on February 10, 2015, at 9:25:27
> I'd try to take just 1 AP/AAP, if you can. I take 30 Abilify, some other stuff, then 2mgs/Risperdal as needed for agitation. Works well for me.
Like C_E says, one antipsychotic is common, taking two is not uncommon, taking three at once is rare. The benefits of such combinations are not documented.
Posted by Chinaboy on February 13, 2015, at 0:13:21
In reply to Re: Please take a look at this combo for schizophrenia, posted by ed_uk2010 on February 10, 2015, at 12:22:07
THank you guys for replying my post. I told my pdoc the above concerns and he had decided to switch me to a Japanese anti-psychotic Lullan(Perospirone) because I cannot afford other three on long term basis.
Lullan is a 5-HT2A/D2 antagonist, 5-HT1A agonist. Today is the third day. So far so good, no side effects, no efficacy, either.
PS: My schizophrenia is simple-type, which is difficult to be diagnosed.
Posted by ed_uk2010 on February 13, 2015, at 11:51:32
In reply to Re: Please take a look at this combo for schizophrenia, posted by Chinaboy on February 13, 2015, at 0:13:21
Chinaboy,
What symptoms are most problematic for you?
Hope perospirone helps.
Posted by Lamdage22 on February 13, 2015, at 12:01:06
In reply to Re: Please take a look at this combo for schizophrenia, posted by Chinaboy on February 13, 2015, at 0:13:21
Sounds interesting.
Let us know how you do.
Posted by burial on February 14, 2015, at 9:40:00
In reply to Re: Please take a look at this combo for schizophrenia, posted by Lamdage22 on February 13, 2015, at 12:01:06
i agree with some of the people here, that it is better to be on a decent dose of a single atypical antipsychotic. Mood stabilizers would be the first augmenting choice followed by a typical antipsychotic for some more dopamine antagonism
Posted by ed_uk2010 on February 17, 2015, at 18:51:42
In reply to Please take a look at this combo for schizophrenia, posted by Chinaboy on February 9, 2015, at 5:41:19
Hi Chinaboy,
I think it would be useful to understand more about your illness.
Have you ever experienced hallucinations? In particular, have you heard voices? Do you ever feel paranoid or that people are against you? Finally, what benefit do you most hope to get from medication?
> schizophrenia (mainly negative symptoms)
What symptoms do you have apart from negative symptoms?
Thanks :)
Posted by Chinaboy on February 20, 2015, at 2:23:08
In reply to Re: Please take a look at this combo for schizophrenia » Chinaboy, posted by ed_uk2010 on February 17, 2015, at 18:51:42
> Hi Chinaboy,
>
> I think it would be useful to understand more about your illness.
>
> Have you ever experienced hallucinations? In particular, have you heard voices? Do you ever feel paranoid or that people are against you? Finally, what benefit do you most hope to get from medication?
>
The diagnosis of me having simple-type schizophrenia is being doubted by many of my previous pdocs now.I have had no hallucination, had no history of being paranoid, and do not feel people are against me.
My symptoms mainly include a lack of motivation (lethargy and laziness), have little feelings or emotions for what I'm experiencing, avoid socialization due to an awkward feeling, care little about my hygienic condition, and could not take good care of myself without help from parents.
The above symptoms arE interpreted as negative psychotic symptoms by a famous pdoc of my province.
What do you think?
Posted by Lamdage22 on February 21, 2015, at 6:29:44
In reply to Re: Please take a look at this combo for schizophrenia, posted by Chinaboy on February 20, 2015, at 2:23:08
I think that negative symptoms equal depression.
Especially in the absence of positive schizophrenia symptoms.
Docs can be weird.
You never had psychosis?
Maybe he thinks you are at risk for psychosis. Its possible. I was before i went on Nardil.
Posted by Lamdage22 on February 21, 2015, at 6:37:09
In reply to Re: Please take a look at this combo for schizophrenia, posted by Lamdage22 on February 21, 2015, at 6:29:44
Just ask him. Its a legitimate question.
Let us know what he says.
Posted by ed_uk2010 on February 22, 2015, at 15:30:37
In reply to Re: Please take a look at this combo for schizophrenia, posted by Chinaboy on February 20, 2015, at 2:23:08
>The diagnosis of me having simple-type schizophrenia is being doubted by many of my previous pdocs now.
It's a rather controversial diagnosis!
In order to give any opinion, we need to know a bit more about you.
What is your mood like? eg. do you feel negative about your situation, or do you really feel nothing? Do you see any hope for the future, or does this not even bother you?
How have your symptoms progressed over time? eg. you had a 'normal' childhood and became unwell later.... or, you have always been the same and never felt much emotion....... or, your illness started after a negative event in your life etc.
What is your age? (only need to know approximately, you don't need to post any personal details)
What were you like as a child? Did you interact with other children back then?
>avoid socialization due to an awkward feeling
What are the awkward feelings like?
>care little about my hygienic condition
Does this apply in all circumstances or just because you're at home and feeling unmotivated? For example, would you feel comfortable about being unwashed while in a social situation, or would this make you feel increasingly awkward?
>The above symptoms are interpreted as negative psychotic symptoms by a famous pdoc of my province.
The concept of negative psychotic symptoms in the absence of psychosis is what's controversial. What treatments have you tried apart from antipsychotics and how did you respond?
Look forward to hearing back from you.
Posted by Chinaboy on February 22, 2015, at 19:26:14
In reply to Re: Please take a look at this combo for schizophrenia » Chinaboy, posted by ed_uk2010 on February 22, 2015, at 15:30:37
> >The diagnosis of me having simple-type schizophrenia is being doubted by many of my previous pdocs now.
>
> It's a rather controversial diagnosis!
>
> In order to give any opinion, we need to know a bit more about you.
>
> What is your mood like? eg. do you feel negative about your situation, or do you really feel nothing? Do you see any hope for the future, or does this not even bother you?
>
> How have your symptoms progressed over time? eg. you had a 'normal' childhood and became unwell later.... or, you have always been the same and never felt much emotion....... or, your illness started after a negative event in your life etc.
>
> What is your age? (only need to know approximately, you don't need to post any personal details)
>
> What were you like as a child? Did you interact with other children back then?
>
> >avoid socialization due to an awkward feeling
>
> What are the awkward feelings like?
>
> >care little about my hygienic condition
>
> Does this apply in all circumstances or just because you're at home and feeling unmotivated? For example, would you feel comfortable about being unwashed while in a social situation, or would this make you feel increasingly awkward?
>
> >The above symptoms are interpreted as negative psychotic symptoms by a famous pdoc of my province.
>
> The concept of negative psychotic symptoms in the absence of psychosis is what's controversial. What treatments have you tried apart from antipsychotics and how did you respond?
>
> Look forward to hearing back from you.Yes, you are right. My new pdoc is also aware that this diagnosis might be inaccurate and asks me to add an antidepressant to go with 4Mg of Risperdal I'm on now.
So I chose Nardil,which I bought from Internet at a rather high price. Do you think that 45Mg of Nardil can go smoothly with 4Mg of Risperdal?
Posted by Chinaboy on February 22, 2015, at 19:38:29
In reply to Re: Please take a look at this combo for schizophrenia » Chinaboy, posted by ed_uk2010 on February 22, 2015, at 15:30:37
> >The diagnosis of me having simple-type schizophrenia is being doubted by many of my previous pdocs now.
>
> It's a rather controversial diagnosis!
>
> In order to give any opinion, we need to know a bit more about you.
>
> What is your mood like? eg. do you feel negative about your situation, or do you really feel nothing? Do you see any hope for the future, or does this not even bother you?
>
> How have your symptoms progressed over time? eg. you had a 'normal' childhood and became unwell later.... or, you have always been the same and never felt much emotion....... or, your illness started after a negative event in your life etc.
>
> What is your age? (only need to know approximately, you don't need to post any personal details)
>
> What were you like as a child? Did you interact with other children back then?
>
> >avoid socialization due to an awkward feeling
>
> What are the awkward feelings like?
>
> >care little about my hygienic condition
>
> Does this apply in all circumstances or just because you're at home and feeling unmotivated? For example, would you feel comfortable about being unwashed while in a social situation, or would this make you feel increasingly awkward?
>
> >The above symptoms are interpreted as negative psychotic symptoms by a famous pdoc of my province.
>
> The concept of negative psychotic symptoms in the absence of psychosis is what's controversial. What treatments have you tried apart from antipsychotics and how did you respond?
>
> Look forward to hearing back from you.Yes, you are right. My new pdoc is also aware that this diagnosis might be inaccurate and asks me to add an antidepressant to go with 4Mg of Risperdal I'm on now.
So I chose Nardil,which I bought from Internet at a rather high price. Do you think that 45Mg of Nardil can go smoothly with 4Mg of Risperdal?
Posted by ed_uk2010 on February 23, 2015, at 14:05:45
In reply to Re: Please take a look at this combo for schizophrenia » ed_uk2010, posted by Chinaboy on February 22, 2015, at 19:38:29
>asks me to add an antidepressant to go with 4Mg of Risperdal I'm on now.
You mean he didn't prescribe one?
>So I chose Nardil, which I bought from Internet at a rather high price. Do you think that 45Mg of Nardil can go smoothly with 4Mg of Risperdal?
I can't really answer any questions about whether Nardil is likely to be safe or suitable for you. Neither can anyone else on the board. To do so would require a lot of knowledge about your case. Please bear in mind that Nardil has a large number of interactions with foods, including Chinese foods.
This is the end of the thread.
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