![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by rjlockhart37 on January 11, 2015, at 14:42:47
hey i read a post you put that zyprexa can cause diabeties, i think you said that it can cause insulin resistance, could this happen with medications? because i've been having reduced effect of my current medications, and i have been researching like crazy...i take them and they hardly have any effect, at first i thought they where not absorbing, then i noticed they did work but it was vary insensitive,
could it of caused this? and if got off it would it make things go back to normal?
Posted by ed_uk2010 on January 11, 2015, at 17:32:42
In reply to ed uk question about zyprexa, posted by rjlockhart37 on January 11, 2015, at 14:42:47
>hey i read a post you put that zyprexa can cause diabeties, i think you said that it can cause insulin resistance, could this happen with medications?
Hi RJ,
Are you asking whether taking Zyprexa could make you resistant to other medications?
If so, that's not at all likely. Resistance to insulin is a process which happens in Type 2 diabetes - which is a risk with various antipsychotics, especially Zyprexa. Zyprexa doesn't cause resistance to other medications however, but some degree of tolerance can occur to its sedating effect over time.
You will be absorbing your medications the same as you always did. Tolerance to the sedating effect occurs due to adaptations within the brain, not due to changes in absorption.
Does this answer your question?
Posted by rjlockhart37 on January 11, 2015, at 23:58:43
In reply to Re: ed uk question about zyprexa » rjlockhart37, posted by ed_uk2010 on January 11, 2015, at 17:32:42
yes, but it's not just one med, it's almost everything i put in my body, energy drinks, coffee, my other medications, it's developed a resistance to almost everything......i've been doing research on things like parasites that can prevent nutrients including medication to not be effective, and i know that sounds a little over the top, but i'm going to have to see my regular doctor to see if i can .... get tested, right now is a bad time because everything including caffeine i put in my body, it does not have hardly any effect, once and while it will work, but this has got me really paranoid researching everything i can for the cause, this is bad time......
get a potent medicine that will kill anything that is using me as a host and causing the gastric problems i have too, i know that sounds crazy, but i am so wiped to figure out a explanation to this.....
someone told me about vitamen D diffiency, im just exploring and researching everything realted to this.......it's making me miserable
ill have to ask the doctor to do a test, and if it detects an organism that has also been causing more problems with stomach, already put together a list of special herbs that are known to kill bacteria, and like parasites......written them down and going to see if i can find them at the central market store
thanks......the zyprexa just causes mild sedation, it used to cause signifcant sedation to where i wanted to sleep all the time......
ill try to figure this out more through google
thanks
Posted by rjlockhart37 on January 12, 2015, at 0:08:29
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 11, 2015, at 23:58:43
sorry i just ranted too much about worries
what do you think could be done?
Posted by ed_uk2010 on January 12, 2015, at 6:30:48
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 11, 2015, at 23:58:43
>yes, but it's not just one med, it's almost everything i put in my body, energy drinks, coffee, my other medications, it's developed a resistance to almost everything......
Caffeine increases Zyprexa blood levels to some extent by inhibiting its metabolism (by CYP 1A2). This is likely to oppose the stimulant effect of the caffeine.
You won't be resistant to everything.... but your current medication will produce some cross-tolerance to drugs with similar actions. As an example, Zyprexa has a strong sedative antihistamine action. Regular use of Zyprexa will therefore produce tolerance to the sedative action of antihistamines. It's nothing to do with absorption, it's do to adaptations in the brain due to continuous exposure to the medication.
Posted by rjlockhart37 on January 12, 2015, at 11:46:47
In reply to Re: ed uk question about zyprexa, posted by ed_uk2010 on January 12, 2015, at 6:30:48
yea......i need to get off zyprexa, im on 20mg and like you said it doesnt cancel out the other medications im taking, but still i have a feeling it has something to do with it.....
like ill have a energy drink or caffeine, it will start to take effect but then it's like an hour later it levelizes it and i don't notice the effect, couple months i was put on hydrocodone for pain for a short time, and the hydrocodone would work but then my body levelizes it to where it's not noticable.....and i know that sounds like im thinking too much but it's something in the blood stream or brain, everyone else notices effects of medication, and it started in 2010 an slowly became insensitive toward the effects of various diffrent drugs.....
it makes me in depressed mood even thinking about it because i don't know what to do
Posted by ed_uk2010 on January 12, 2015, at 15:44:14
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 12, 2015, at 11:46:47
>like ill have a energy drink or caffeine, it will start to take effect but then it's like an hour later it levelizes it and i don't notice the effect....
That's normal RJ. Many people barely notice caffeine.
>couple months i was put on hydrocodone for pain for a short time, and the hydrocodone would work but then my body levelizes it to where it's not noticable.....
That's normal. Tolerance to opioids develops rapidly in many people. This isn't due to Zyprexa. Tolerance to hydrocodone is caused by taking hydrocodone (or other opioids).
>everyone else notices effects of medication.....
Which medication? Other people develop tolerance too.
Specifically, which medication do you want to be more sensitive to and why? What effect do you want?
Posted by rjlockhart37 on January 12, 2015, at 17:52:07
In reply to Re: ed uk question about zyprexa » rjlockhart37, posted by ed_uk2010 on January 12, 2015, at 15:44:14
im basically talking about all my medications, zyprexa is the only one that seems to work, at night it causes drowsiness and some impaired thinking, which is why i think i need to get off zyprexa
all the other medications im on have little to no effect and it's a problem that has caused me problems since 2010, i've gotten seriouly depressed over this period of time, hardly any medications that i have switched to, my body creates where it doenst have any effect, it's simple as that......there's no tolerance, because even if i took something for the first time, lyrica at high doses, it had no effect, and was exactly like a placebo, it's not tolerance.....and frankly im tired of trying to figure out something that is simple, that it is a problem and it's not normal at all, i don't want to undersimplify something that causing severe depression and mood swings
ill talk with my doctor, but they won't know much, until all these expensive tests are done, which i don't want to do....
thanks for the post
Posted by rjlockhart37 on January 12, 2015, at 18:01:10
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 12, 2015, at 17:52:07
these are my current meds
Prozac 60mg
Lamictal 400mg
Nuvigil 250mg
Zyprexa 20mgi do notice once and a while.....the prozac does keep me from being depressed, but it goes in a phase where it works and then doesnt work for a long time......and alot of it, i have been worried about is through the absorbation in the stomach, or something nuertralizing the effect.....
nuvigil is the same thing....it will work maybe ... vary short time and then it get's canceled out, i fall back to sleep like i didnt take anything.......deep sleep
it' a vary difficult period right now, trying to find awnsers, then getting more miseerable
spiritual healing i've been looking into
Posted by ed_uk2010 on January 13, 2015, at 5:30:42
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 12, 2015, at 18:01:10
> these are my current meds
> Prozac 60mg
> Lamictal 400mg
> Nuvigil 250mg
> Zyprexa 20mg
>
> i do notice once and a while.....the prozac does keep me from being depressed, but it goes in a phase where it works and then doesnt work for a long time......I don't 'notice' my medication RJ. You're not really supposed to 'notice' most psychiatric medications - that's not the idea. On the other hand, if you think they are not keeping you well, you may need to look at other options, which may or may not involve medication.
>i have been worried about is through the absorbation in the stomach, or something nuertralizing the effect.....
It's not that. Antidepressants often don't work, that's just reality. It's not because they're not absorbed, it because what they do in the brain isn't always what you need them to do to relieve your symptoms.... and in some cases no medication will relieve your symptoms well because certain symptoms are dependent on your life situation.
I don't 'notice' SSRIs. Many people who take them long-term don't. And it's very common not to 'notice' Lamictal. As for Nuvigil, I've not tried it. I don't notice Provigil much. I think you're expecting things which often don't happen - your experience of not noticing your medication is not unusual. Taking Nuvigil isn't supposed to be like a cocaine injection! Also, the role of Nuvigil in psychiatry isn't clear. It is not approved for any psychiatric disorder, nor is it approved for reducing drowsiness caused by psychiatric medication.
>it' a vary difficult period right now, trying to find awnsers, then getting more miseerable
Well, what are your symptoms? Do you have a diagnosis? Are your circumstances are home or work difficult? Why are you taking so much Zyprexa?
Posted by rjlockhart37 on January 13, 2015, at 14:13:51
In reply to Re: ed uk question about zyprexa, posted by ed_uk2010 on January 13, 2015, at 5:30:42
just when i started prozac it signifcantly provided relief from depression, don't know if the body and mind just adapted to it, maybe it did, not sure........
the nuvigil works sometimes, other times it doesnt owrk at all and i go through out the day in sleep state, becausee of zyprexa.....zyprexa is the only one that i can tell a large effect because of the sedation, yet, sometimes it will not do the same thing on certain days, and my fretting about not being aborbed is because of that.......your right it could totally not be the absorbation problem, i've worried about that for long time.....
the reason i took zyprexa is in 2010 i admitted myself to hospital, because i went through a phase where i thought satan was trying to control my mind, i went to a church and asked for help and they thoughts i was just worrying too much, and then the previous year in 2009 i went through a paranoia phase that everytime i left the house the same cars would follow me, it seemed like they where trying to harrass me on the road, then when i would go into stores, my mind thought they where following me, trying to get information to throw me in jail......i thought the whole neighboor hood was planning to harrass me to where i coucldnt leave the house with out being harrassed, that period ended and the stuff that went on during the period was vary strange, it disappeared later in 2010, and i went back to being myself, they put me on zyprexa because of that, originally the previous doctor before the hospital put me on zyprexa 10mg and geodon 160mg, in the morning, it made me totally wiped out.....got off geodon, but continued zypresxa and it was increased at the psych hospti. to 20mg and since then i've been on it, i need to get off it......it's so sedating, yet the other medcines have no effect, expept zyprexa.....
so....
spiritual healing i've been researching about for this problem, and eventually change meds but why im not changing is because it seems all psych meds i take have little effect
thats why......
r
Posted by rjlockhart37 on January 13, 2015, at 14:44:23
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 13, 2015, at 14:13:51
the nuvgil was given for day time drosiness caused by zyprexa.....with or without it.....my doctor thought i would be a good option to increase back to normal effect, with out the sedation of zyprexa.....
nuvgil just promotes wakefulness.....of course it's not a cocaine injection or methamphetamine, nuvigil is not at all linked to them, it just promotes wakefulness, i know because methamphetamine through the crsytal form makes you crazy and do things that are insane, hyperfocus, and too much stimulation
Posted by ed_uk2010 on January 14, 2015, at 0:54:01
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 13, 2015, at 14:44:23
> nuvgil just promotes wakefulness.....of course it's not a cocaine injection or methamphetamine, nuvigil is not at all linked to them, it just promotes wakefulness, i know because methamphetamine through the crsytal form makes you crazy and do things that are insane, hyperfocus, and too much stimulation
I know. It was just a comparison because cocaine is a drug which most people would 'feel' a marked effect from. Psychiatric drugs are not necessarily like that. People may or may not notice their effects very much on a daily basis. The fact that you don't notice your meds a great deal is not unusual.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.