Posted by ed_uk2010 on January 12, 2015, at 6:30:48
In reply to Re: ed uk question about zyprexa, posted by rjlockhart37 on January 11, 2015, at 23:58:43
>yes, but it's not just one med, it's almost everything i put in my body, energy drinks, coffee, my other medications, it's developed a resistance to almost everything......
Caffeine increases Zyprexa blood levels to some extent by inhibiting its metabolism (by CYP 1A2). This is likely to oppose the stimulant effect of the caffeine.
You won't be resistant to everything.... but your current medication will produce some cross-tolerance to drugs with similar actions. As an example, Zyprexa has a strong sedative antihistamine action. Regular use of Zyprexa will therefore produce tolerance to the sedative action of antihistamines. It's nothing to do with absorption, it's do to adaptations in the brain due to continuous exposure to the medication.
poster:ed_uk2010
thread:1075059
URL: http://www.dr-bob.org/babble/20150102/msgs/1075069.html