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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by doxogenic boy on September 8, 2013, at 16:33:16
As mentioned in an earlier post, I am very satisfied with my combo of six drugs, one of them Stablon (branded tianeptine), but now a pharmacist at my local pharmacy says they are not allowed to import Stablon from Austria to Norway any longer, so I have to start using a generic tianeptine from Germany Tianeurax.
Here is an article: Generic vs. Branded Drugs: Just How Equal Is Equal?
http://www.aao.org/publications/eyenet/201106/upload/CUcomp-June-2011.pdf
Can I risk to lose the effect from tianeptine when I change from Stablon to the same dose of Tianeurax, or can I risk side effects? Are there anyone out there who have used Stablon and changed to Tianeurax and how did it work? Tianeurax is from the company neuraxpharm in Germany do anyone know if they are reliable?
It is my worst nightmare if my anxiety and depression return because of a generic like this.
- doxogenic
Posted by europerep on September 9, 2013, at 12:46:20
In reply to Changing from Stablon to Tianeurax, a generic, posted by doxogenic boy on September 8, 2013, at 16:33:16
Hi,
Neuraxpharm is a relatively big manufacturer of psychiatric generic drugs, I have used their products without any problems.
I would suggest that, if possible, you switch gradually, i.e. replace one tablet of your previous brand by one tablet of Tianeurax, see how it works, and then move further. It's likely that you'll have no difficulties at all.
ER
Posted by doxogenic boy on September 9, 2013, at 15:24:04
In reply to Re: Changing from Stablon to Tianeurax, a generic » doxogenic boy, posted by europerep on September 9, 2013, at 12:46:20
Hello,
Thank you for sharing your experiences, this makes me more relieved. Isn't neuraxpharm's introduction of Tianeurax the first time you can get tianeptine in Germany? http://www.pharmazeutische-zeitung.de/index.php?id=44354
Are there many Tianeurax users there?
Posted by sigismund on September 9, 2013, at 15:36:42
In reply to Changing from Stablon to Tianeurax, a generic, posted by doxogenic boy on September 8, 2013, at 16:33:16
I think I have used Coaxal (if that is the brand name), and it was fine.
I did not know there was generic tianeptine or not.
Posted by europerep on September 9, 2013, at 16:18:01
In reply to Re: Changing from Stablon to Tianeurax, a generic » europerep, posted by doxogenic boy on September 9, 2013, at 15:24:04
> Isn't neuraxpharm's introduction of Tianeurax the first time you can get tianeptine in Germany?
Yes, that is correct, in Germany it hasn't been available in any form before a year or two ago. The drug itself is much older of course, but if you have researched it a little, you probably know all that better than me. ;)
> Are there many Tianeurax users there?
I have only "met" one, on a different forum. It didn't work well for him, and actually I know few people who have been using tianeptine successfully. But I'd say that if it works for you, that's what counts.
Posted by doxogenic boy on September 9, 2013, at 18:46:59
In reply to Re: Changing from Stablon to Tianeurax, a generic, posted by sigismund on September 9, 2013, at 15:36:42
> I think I have used Coaxal (if that is the brand name), and it was fine.
What kind of tianeptine do you use now, have you used different brands and if so, did you feel any difference? On this site it says that both Stablon, Coaxil and Tatinol are tianeptine brand names of Servier, but Neluptin and Salymbra seems to be generic:
http://www.drugs.com/international/tianeptine.html
On Servier's international site I only find Stablon.
http://servier.com/product-portfoliohttp://servier.com/sites/default/files/SPC_Stablon.pdf
I found an interesting thing about pharmacodynamic properties on the pdf site above:
"In animals,Tianeptine has the following properties: Tianeptine increases the spontaneous activity of pyramidal cells in the hippocampus and
accelerates their recovery after functional inhibition,"I didn't know that this was official. And I wonder if it is because of this study:
http://www.pnas.org/content/98/22/12796.full?sid=1738dff0-e188-46f8-a688-2daba3a6d530
"Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine"
> I did not know there was generic tianeptine or not.Here is about the generic drug manufacturer neuraxpharm:
http://www.neuraxpharm.de/html-de/unternehmen-anders.php
and Tianeurax:
http://www.neuraxpharm.de/html-de/erkrankungen-praeparate-detailansicht.php?name=Tianeurax
http://www.neuraxpharm.de/download-pil.php?pfad=GI_Tianeurax_12_5_mg_-_368_2.pdf
Posted by doxogenic boy on September 9, 2013, at 18:51:38
In reply to Re: Changing from Stablon to Tianeurax, a generic » doxogenic boy, posted by europerep on September 9, 2013, at 16:18:01
> > Isn't neuraxpharm's introduction of Tianeurax the first time you can get tianeptine in Germany?
>
> Yes, that is correct, in Germany it hasn't been available in any form before a year or two ago. The drug itself is much older of course, but if you have researched it a little, you probably know all that better than me. ;)Ok. :)
> > Are there many Tianeurax users there?
>
> I have only "met" one, on a different forum. It didn't work well for him, and actually I know few people who have been using tianeptine successfully.Maybe it works better as an adjunctive? I know of one positive case report, from Austria with a sertraline/amitriptyline/carbamazepine/tianeptine combo, which I have quoted from in this post:
http://www.dr-bob.org/babble/20090826/msgs/914964.html
>But I'd say that if it works for you, that's what counts.Yes, I agree with that.
- doxogenic
Posted by sigismund on September 9, 2013, at 21:23:00
In reply to Re: Changing from Stablon to Tianeurax, a generic, posted by doxogenic boy on September 9, 2013, at 18:46:59
I've only used Coaxal and Stablon. They seemed the same. It is expensive, especially at higher doses. I did try agomelatine with it but that did not improve things. Tianeptine has a mood brightening quality which is good for me.
Posted by Riloal on September 14, 2013, at 4:47:51
In reply to Re: Changing from Stablon to Tianeurax, a generic, posted by sigismund on September 9, 2013, at 21:23:00
doxogenic boy, i.m using tianeptine with succes. I,m using coaxil. The only problem it,s i,m noticing thinning and hair loss. Do you have this side effect? Thanks
Posted by doxogenic boy on September 16, 2013, at 10:10:31
In reply to Re: Changing from Stablon to Tianeurax, a generic, posted by Riloal on September 14, 2013, at 4:47:51
> doxogenic boy, i.m using tianeptine with succes. I,m using coaxil. The only problem it,s i,m noticing thinning and hair loss. Do you have this side effect? Thanks
No, I haven't those side effects. Do you use tianeptine as monotherapy? What doses do you use? Great that it works for you.
- doxogenic
Posted by Riloal on September 17, 2013, at 4:39:00
In reply to Re: Changing from Stablon to Tianeurax, a generic » Riloal, posted by doxogenic boy on September 16, 2013, at 10:10:31
Hi, i use tianeptine cause i,m suffer from anhedonia and little depression from using ritalin for my ADHD. My dose is two coaxil in the morning and one after lunch. What is yoour regimen? How long have you been on coaxil? Thanks
Posted by doxogenic boy on September 17, 2013, at 7:24:08
In reply to Re: Changing from Stablon to Tianeurax, a generic, posted by Riloal on September 17, 2013, at 4:39:00
> Hi, i use tianeptine cause i,m suffer from anhedonia and little depression from using ritalin for my ADHD. My dose is two coaxil in the morning and one after lunch. What is yoour regimen? How long have you been on coaxil? Thanks
I take 4 tablets of Stablon (Coaxil, Tianeurax) 6 times a day, 24 tablets daily. I have been on Stablon continuously since September 22, 2008, but I have also had earlier sessions of Stablon. I have used 24 tablets a day since October 25, 2009, and I am very satisfied. You can see my combo of six drugs in my signature below.
- doxogenic
Posted by Riloal on September 17, 2013, at 7:41:50
In reply to Re: Changing from Stablon to Tianeurax, a generic » Riloal, posted by doxogenic boy on September 17, 2013, at 7:24:08
That,s a heavy dose of Stablon. Never tried to stopped for a while? I have been continuosly since this february, and i need now that i must up the dose, but perhaps if i stay off for a week, my tolerance will be reduced. Do you developed a tolerance to tianeptine? So in all these years you never had a problem with thinning or hair loss? I guess now that mine could be thyroid related. Your information it,s very helpful. I order my tianeptine from brandmedicines.com i think they sell a good brand of coaxil.
Posted by doxogenic boy on September 17, 2013, at 13:41:25
In reply to Re: Changing from Stablon to Tianeurax, a generic, posted by Riloal on September 17, 2013, at 7:41:50
> That,s a heavy dose of Stablon. Never tried to stopped for a while? I have been continuosly since this february, and i need now that i must up the dose, but perhaps if i stay off for a week, my tolerance will be reduced. Do you developed a tolerance to tianeptine?
I have used the same dose of Stablon since October 25, 2009, I have never tried to stop, and I have had the same effect all the time, no tolerance build up.
> So in all these years you never had a problem with thinning or hair loss?
I have never had hair loss. By "thinning", do you mean weight loss? Since I use trimipramine and quetiapine I have gained some weight.
>I guess now that mine could be thyroid related. Your information it,s very helpful.
Thank you for your response, I find it very interesting to discuss the use of psychotropics.
>I order my tianeptine from brandmedicines.com i think they sell a good brand of coaxil.
I don't know about how internet pharmacies work, I get all my medicine from my local pharmacy. Servier, the manufacturer of Stablon, says that they don't sell medicines over the internet:
http://servier.com/servier-does-not-sell-its-products-over-the-internet- doxogenic
This is the end of the thread.
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