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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Novelagent on August 10, 2012, at 12:52:02
Someone on this site suggested that not gettig type II diabetes while on Zyprexa was a matter of watching what one ate, and I'm here to explain that's a myth-- a very wise doctor explained it to me, and it was over my head, but basically, Zyprexa short circuits metabolism so that even without weight gain, it can cause diabeties-- it is not secondary to weight gain, although of course, weight gain alone increases one's risk in the sense it adds on to the risk, it's not necessary to gain weight to get diabeties fron drugs with the generic name ending in -pine, such as Zyprexa (olazapine). Seroquel is another...
It alarms me how so many on this board have doctors who don't know what they're doing, and as a result, put their patients on Zyprexa. Risperdal or Invega are better options-- ideally, Invega Sustenna is the best, as it is just a once-a-month injection, and research shows that one needs a lower dose of a long-acting injection over time than an oral for
of the same drug.I take Invega Sustenna-- it's great, because I don't have to worry about forgetting it, since I just have to take it once a month.
Anyhow, a lot of you are at risk of getting type II diabeties and may not even know this, but your doctor should. It makes no sense-- Zyprexa or Seroquel have no clinical advantage over Risperdal, so it's not even a justified risk.
I initially was on Zyprexa oral capsules, but the regular hospitals were "full" (meaning the nurse at the ER was too lazy to call more than one psych hospital) so I got stuck in a hospital intended only for drug rehab. So my paychiatrist was specializing in treating drug addicts, not psychosis. But I don't know the excuse for your doctors. I went to a psych hospital shortly after that, and got switched immediately to Risperdal Consta (but even the rehab doc should have realized the importance of a long-acting injection).
Posted by rjlockhart37 on August 10, 2012, at 15:08:13
In reply to Zyprexa can cause diabetes w/o weight gain, posted by Novelagent on August 10, 2012, at 12:52:02
yea novel.... I think I have DI type...because of years of zyprexa at moderate doses...just scroll up...you'll see my post of these symptoms, fatigue, disoriented, low energy, trouble with thoughts....its gotta be the most evidencual causes of this. I gotta get bloodwork done.
That's why medications don't take effect because in DI the glucose doesnt absorb into the cells, including other substances.
im really angry about this....my body just causes all these problems, over and over....
rj
Posted by Novelagent on August 10, 2012, at 18:13:54
In reply to Re: Zyprexa can cause diabetes w/o weight gain, posted by rjlockhart37 on August 10, 2012, at 15:08:13
If you had diabetes, you'd be urinating a lot. Psych meds don't actually work to begin with, so it's not you. You're working under the assumption antidepressants and things work, and we all know that doesn't happen, even psychiatrists who prescribe them will admit they don't actually work.
> yea novel.... I think I have DI type...because of years of zyprexa at moderate doses...just scroll up...you'll see my post of these symptoms, fatigue, disoriented, low energy, trouble with thoughts....its gotta be the most evidencual causes of this. I gotta get bloodwork done.
>
> That's why medications don't take effect because in DI the glucose doesnt absorb into the cells, including other substances.
>
> im really angry about this....my body just causes all these problems, over and over....
>
> rj
Posted by Phillipa on August 10, 2012, at 18:37:32
In reply to Re: Zyprexa can cause diabetes w/o weight gain, posted by Novelagent on August 10, 2012, at 18:13:54
For some they do me not being one of them. Glad I never took an antipsychotic. If not psychotic why take one. Benzos are better. At least they don't cause diseases that I know Of. P
Posted by SLS on August 10, 2012, at 19:12:24
In reply to Zyprexa can cause diabetes w/o weight gain, posted by Novelagent on August 10, 2012, at 12:52:02
> Zyprexa or Seroquel have no clinical advantage over Risperdal, so it's not even a justified risk.
...except in those cases where Zyprexa or Seroquel works but risperidone does not. Risk vs benefit. For some, there is no benefit in taking risperidone. It just doesn't do the job. Each of the APs have their disadvantages. Risperidone can cause an accumulation of abdomninal fat, hyperprolactinemia, and an increased rate of breast cancer. Risperidone is also capable of precipitating diabetes, although not at as high a rate as Zyprexa. The risk of diabetes seems to be dose-dependent. Of the atypical neuroleptic antipsychotics, I believe risperidone has a greatest risk of producing tardive dyskinesia. However, this, too, is dose-dependent.
- Scott
Posted by Novelagent on August 10, 2012, at 20:40:34
In reply to Re: Zyprexa can cause diabetes w/o weight gain » Novelagent, posted by Phillipa on August 10, 2012, at 18:37:32
> For some they do me not being one of them. Glad I never took an antipsychotic. If not psychotic why take one. Benzos are better. At least they don't cause diseases that I know Of. P
>I can't imagine anyone resorting to an antipsychotic for anxiety. For one, benzos work, and another, antipsychotics don't work on anxiety, and certainly don't justify the side effects even if they did work.
I have psychosis, but yeah, I mean some people swear by them for depression, but I think that's a little overkill, especially if one hasn't at least tried emsam first.
Posted by rjlockhart37 on August 12, 2012, at 21:24:51
In reply to Re: Zyprexa can cause diabetes w/o weight gain, posted by Novelagent on August 10, 2012, at 20:40:34
novel, the only reason I am taking zyprexa was because the doctors avoided lorazpeam when I asked for something for anxiety. I disclosed to them of my anxiety that is disableing they refused, and kept mentioning that they knew that antipsycotics would be better That was the only thing I could choose....so I had to pick between risperdal and zyperxa and choose zyprexa....i mean do you really think I am enjoying taking these stupid antipsychotics? there lovely...
anways...sometimes I just play along with my pdoc bunch of s h i t meds that don't work. It's like in rehab you jsut have to go with what they say and then when its over you can do your own thing, im just waiting for my doctor realize how much stress and distress there causing but of course they live in denial that there always right. You just gotta play along with these people.
rj
Posted by Zyprexa on August 12, 2012, at 22:50:00
In reply to Zyprexa can cause diabetes w/o weight gain, posted by Novelagent on August 10, 2012, at 12:52:02
any AAP can cause diabetes. YOu just never know till you take it.
Posted by jono_in_adelaide on August 14, 2012, at 1:27:51
In reply to Re: Zyprexa can cause diabetes w/o weight gain » Novelagent, posted by Phillipa on August 10, 2012, at 18:37:32
Sometimes, one drug will work where another one doesnt - say reiperdel doesnt work, but zyprexa does, surely ity'd be better to be sane and happy with type 2 diabeties than raving mad with excelent blood sugar
Posted by Novelagent on August 18, 2012, at 12:10:49
In reply to Re: Zyprexa can cause diabetes w/o weight gain, posted by Zyprexa on August 12, 2012, at 22:50:00
> any AAP can cause diabetes. YOu just never know till you take it.
That's not true. Type II diabeties has been quantified as a measurable risk factor, and studies have shown risperdal and invega carries a far lesser risk of it than drugs with generic name ending in -pine (seroquel, which is quineptine, and zyprexa, etc.)
Posted by DanielJ on August 22, 2012, at 10:35:34
In reply to Re: Zyprexa can cause diabetes w/o weight gain, posted by Novelagent on August 18, 2012, at 12:10:49
I believe it can in small doses. However since excessive weight gain can be closely related to the onset of diabetes, the effect of Zyprexa w/o weight gain would have to be studied further. My son has been taking Zyprexa since 2004. About 6 months ago he tried Latuda and then Saphris. He was taking 15 mg Zyprexa and just couldn't drop Zyprexa because of horrible withdrawal symptoms. Has any log term user of Zyprexa been able to go off it. It's very addictive. Anyway after trying those meds for a month or so each, he wanted to get back on Zyprexa. Since then he has gained 40 lbs.
This is the end of the thread.
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