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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by mrm1036 on February 4, 2010, at 6:06:26
I've suffered from Major Depression as long as I'm an adult. Right now I'm on the following:
100 mg of Parnate
5 mg of Abilify
3 mg of Lunesta,
and 250 mg of LamictalMy psychiatrist has been wary to push the Parnate to the dose I'm but he has. He added Nuvigil but I quickly built up a tolerance to it (this is true with all the stimulant medications he's tried).
The Parnate is somewhat effective but he and I are searching for another medication to bring me up a bit more (I lose my "gusto" in the middle of the day). Is adding either desipramine or nortriptyline safe? I've mentioned it to him and again he sames wary of doing so?
Has anyone else been on Parnate AND another antidepressant or "boost" medication"?
Thanks again.
Posted by Maxime on February 4, 2010, at 9:38:03
In reply to Re:Supplenent to Parnate?, posted by mrm1036 on February 4, 2010, at 6:06:26
I'm on 100 mg of Parnate and 75 mg of Nortrip. I was doing really well on this combo until a few weeks ago but something in my life happened that made me very sad. So it is safe to add the Nortriptyline.
Posted by bleauberry on February 4, 2010, at 18:04:54
In reply to Re:Supplenent to Parnate?, posted by mrm1036 on February 4, 2010, at 6:06:26
Nort and Desip can go with Parnate. Others here have done it. Contrary to unfounded fears, there is actually some benefit not usually mentioned. That is, the TCAs block much of the tyramine risk of Parnate.
To find out more, go to psychotropical.com. The doctor there has some excellent writings on Parnate that explains these kinds of things in detail.
Posted by mrm1036 on February 4, 2010, at 20:28:35
In reply to Re:Supplenent to Parnate?, posted by bleauberry on February 4, 2010, at 18:04:54
Thanks to each of you for your responses.
My major symptom of major depression is lethargy, which is one reason my psychiatrist prescribed Parnate.
From the limited reading I've done, it seems that Vivactil is a "stimulating" TCA (although I may be incorrect. Has had Vivactil added to Parnate?
Thanks again.
Posted by willey on February 4, 2010, at 21:45:02
In reply to Re:Supplenent to Parnate?, posted by mrm1036 on February 4, 2010, at 6:06:26
Yess augmenting parnate seems to be a bible commandent in its use.
I can only recomend what i use/or have used.
Mirapex is a dopamine agonist,rasise dopamine.
You can use something like adderall,but personaly i recomend it used sparingly,like 2 x week.
I recently added a dirt cheap med called camprel,its a gaba modulator and increases sociability ten fold,i had to cut back as i just wanted to talk.
Something simple is pure caffiene,not from a bevarage,but from vivaran at your local store,a half of tab of 250 mg sometimes helps add a little mind kick.
Nortrip is safe and popular,dident help me but everyone is different,but mirapex i became interested in cause it hits the target of dopamine called i believe the acumbens which is the pleasure part of the brain.
Many options,try to form a cocktail with ur everyday parnate dose,then your sedative,ur augment etc,and dose that cocktail 2x day rather then just spreading out meds in the day.
There is so much i cant type,ive been working with parnate 5 years and it never ends,im always tweaking my cocktail,but since i got it to be more then half effective,usualy i just have to add a single agent or so.
Oh also forgot a med called olmifon,which is legally allowed to purchase no script,sources are everywhere,it is a cousin to modfanil.
Also something that i add legaly i cant,but it s a shame,it in a word ACTIVATES my combo and without it my combo would be sorta dead.
This substance i speak of ,well all i can say is its natural,now illegal withoutscript,and basicaly adds gaba and dopamine to the brain.
Campral is a drug most docs wont give which is a shame,if anyone here simply read its full method of action,the simplicity of it,theyd see how it could be a benifit with any med cocktail,yet its used specficaly for alcoholism.
What the drug does is restore balace between glutamte and gaba,which makes u calm prob via the gaba and also makes u alert and mentaly stimulated which is prob via the glutamte,so there is no over load of either,causing no sedation like gaba meds,and no anxiety oro toxic effect such as in glutamte rasing drugs.
Posted by bulldog2 on February 6, 2010, at 12:44:54
In reply to Re:Supplenent to Parnate?, posted by willey on February 4, 2010, at 21:45:02
> Yess augmenting parnate seems to be a bible commandent in its use.
>
> I can only recomend what i use/or have used.
>
> Mirapex is a dopamine agonist,rasise dopamine.
>
> You can use something like adderall,but personaly i recomend it used sparingly,like 2 x week.
>
> I recently added a dirt cheap med called camprel,its a gaba modulator and increases sociability ten fold,i had to cut back as i just wanted to talk.
>
> Something simple is pure caffiene,not from a bevarage,but from vivaran at your local store,a half of tab of 250 mg sometimes helps add a little mind kick.
>
> Nortrip is safe and popular,dident help me but everyone is different,but mirapex i became interested in cause it hits the target of dopamine called i believe the acumbens which is the pleasure part of the brain.
>
> Many options,try to form a cocktail with ur everyday parnate dose,then your sedative,ur augment etc,and dose that cocktail 2x day rather then just spreading out meds in the day.
>
> There is so much i cant type,ive been working with parnate 5 years and it never ends,im always tweaking my cocktail,but since i got it to be more then half effective,usualy i just have to add a single agent or so.
>
> Oh also forgot a med called olmifon,which is legally allowed to purchase no script,sources are everywhere,it is a cousin to modfanil.
>
> Also something that i add legaly i cant,but it s a shame,it in a word ACTIVATES my combo and without it my combo would be sorta dead.
>
> This substance i speak of ,well all i can say is its natural,now illegal withoutscript,and basicaly adds gaba and dopamine to the brain.
>
> Campral is a drug most docs wont give which is a shame,if anyone here simply read its full method of action,the simplicity of it,theyd see how it could be a benifit with any med cocktail,yet its used specficaly for alcoholism.
>
>
> What the drug does is restore balace between glutamte and gaba,which makes u calm prob via the gaba and also makes u alert and mentaly stimulated which is prob via the glutamte,so there is no over load of either,causing no sedation like gaba meds,and no anxiety oro toxic effect such as in glutamte rasing drugs.Yes parnate does take you out of depression, often very rapidly. But It does leave me with the feeling that something is till missing. The happy pro social feeling that makes one want to interact with the environment.
Posted by willey on February 6, 2010, at 16:20:57
In reply to Re:Supplenent to Parnate? » willey, posted by bulldog2 on February 6, 2010, at 12:44:54
Lol we sound very similiar in our illness.
Posted by mrm1036 on February 8, 2010, at 6:07:45
In reply to Re:Supplenent to Parnate?, posted by willey on February 4, 2010, at 21:45:02
Thanks again to you all.
I'll be talking with my psychiatrist about the possibility of augmenting Parnate with some of the suggestions made in this thread.
Thanks again.
Posted by willey on February 8, 2010, at 11:34:09
In reply to Re: Parnate and Provigil/NUVIGIL?, posted by mrm1036 on February 8, 2010, at 6:07:45
> Thanks again to you all.
>
> I'll be talking with my psychiatrist about the possibility of augmenting Parnate with some of the suggestions made in this thread.
>
> Thanks again.The one in your headline should be fine,i personaly did it,and know others who have.
This is the end of the thread.
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