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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by jms600 on August 30, 2009, at 12:29:14
This is just a thought, but if benzos aren't helping my anxiety does Lyrica/pregabalin stand any chance? Surely they work on the same part of the brain and hence if benzos don't relieve the anxiety then neither will Lyrica??
Am I correct or completely wrong?!?
Posted by willyeee on August 30, 2009, at 12:36:56
In reply to A thought on Lyrica and benzos...., posted by jms600 on August 30, 2009, at 12:29:14
> This is just a thought, but if benzos aren't helping my anxiety does Lyrica/pregabalin stand any chance? Surely they work on the same part of the brain and hence if benzos don't relieve the anxiety then neither will Lyrica??
>
> Am I correct or completely wrong?!?I found klonopin and gabapentin,the early cousin of lyrcia,the cheaper one,to all most have a synergy.
Most stablizers have a end result of simply making more gaba available in the nogon,more gaba benifits benzos to work more potently.So in short,i will say this,yess i agree replacment of a benzo with a stablizer is less likly in most cases to cease anxiety,the two alone how might possably hold a nice synergy one that can stop anxiety dead in its tracks.
For myself i found this to be klonopin and gabpentin,lyrcia is a hyped up cousin more expensive and overly potent in my view.
Posted by willyeee on August 30, 2009, at 12:40:47
In reply to Re: A thought on Lyrica and benzos...., posted by willyeee on August 30, 2009, at 12:36:56
Let me make clear "i feel stablizers alone will less likly produce anxiety relieaf then a benzo,HOWEVER the two in combo can often creat a synergy the stablizer acting like a gaba pillo to make the benzo more stable and potent,i found this true of the klonopin/gabpentin combo"thanks.
Posted by Phillipa on August 30, 2009, at 12:47:11
In reply to Re: A thought on Lyrica and benzos...., posted by willyeee on August 30, 2009, at 12:40:47
Will I've heard lyrica can relieve anxiety when benzos fail let me search I'm now the google Queen. Phillipa
Posted by Phillipa on August 30, 2009, at 12:53:27
In reply to Re: A thought on Lyrica and benzos...., posted by willyeee on August 30, 2009, at 12:36:56
My search so far wow check this one out interesting. First I've read of this encouraging to me. Phillipa
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1076447
Posted by Sunbath on August 30, 2009, at 14:49:46
In reply to Re: A thought on Lyrica and benzos...., posted by willyeee on August 30, 2009, at 12:40:47
Hi jms!
I was also very interested in Lyrica and from what I've read, Lyrica doesn't work "at the same site" as Benzos nor does it mimic gaba. And it doesn't just only increase gaba levels either.. it does a lot of other things.. so it could work I think.
Good luck to you!!
Posted by willyeee on August 30, 2009, at 15:20:16
In reply to Re: A thought on Lyrica and benzos.... » willyeee, posted by Phillipa on August 30, 2009, at 12:47:11
> Will I've heard lyrica can relieve anxiety when benzos fail let me search I'm now the google Queen. Phillipa
The article clearly is not a fan of benzos.Not to say lyrcia is one of the newer and most potent meds out there and the posability of anxiety relieaf alone does stand,it still remains uncommon that a mood stablizer over a benzo will hold greater anxiety relieaf
Also you emailed me then used it aganist me before,now you start this post using my real name,not that i even mind that but perhaps it best you avoid my posts,isnt it uncivil to use a posters real name or why then do we even have posting handles.
Posted by SLS on August 30, 2009, at 16:22:57
In reply to Re: A thought on Lyrica and benzos...., posted by Sunbath on August 30, 2009, at 14:49:46
> Hi jms!
>
> I was also very interested in Lyrica and from what I've read, Lyrica doesn't work "at the same site" as Benzos nor does it mimic gaba. And it doesn't just only increase gaba levels either.. it does a lot of other things..That's a real good synopsis. I don't know all of the things that Lyrica does. I do know that it binds to the alpha2delta subunit of the voltage-gated calcium channel and inhibits it. Neurontin does the same thing. To my knowledge, neither drug influences sodium channel function.
My brain does not like either of these two drugs. They make my depression worse and make me feel like a zombie. What's worse, is that I continue to experience these things long after I discontinue the drugs.
- Scott
Posted by antigua3 on August 30, 2009, at 19:18:13
In reply to A thought on Lyrica and benzos...., posted by jms600 on August 30, 2009, at 12:29:14
I take Lyrica and Klonopin together and it works well for me.
antigua
Posted by Phillipa on August 30, 2009, at 19:51:57
In reply to Re: A thought on Lyrica and benzos...., posted by willyeee on August 30, 2009, at 15:20:16
Typo was meant to say Well. Phillipa
Posted by Phillipa on August 30, 2009, at 19:55:12
In reply to Re: A thought on Lyrica and benzos.... » jms600, posted by antigua3 on August 30, 2009, at 19:18:13
Antigua any weight gain from lyrica and what dose? Heard the lower doses more for anxiety and higher doses for depression Thanks Phillipa
Posted by antigua3 on August 31, 2009, at 21:31:25
In reply to Re: A thought on Lyrica and benzos.... » antigua3, posted by Phillipa on August 30, 2009, at 19:55:12
No weight gain. 150 mg/day for anxiety.
antigua
Posted by Phillipa on September 1, 2009, at 20:25:47
In reply to Re: A thought on Lyrica and benzos.... » Phillipa, posted by antigua3 on August 31, 2009, at 21:31:25
Antiqua seriously no weight gain that is great news. Thanks Love Phillipa
This is the end of the thread.
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