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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by pedr on August 13, 2009, at 15:07:46
Hi,
found this on pubmed and thought it may be of use since there's so much confusion out there regarding Nardil and beer.The upshot is that in their study of 49 tap beers and 49 bottled beers, only a 4 tap beers were problematic and none of the bottled beer was. Their recommendation is to avoid tap beer and to keep bottled beer consumption to less than 4 bottles.
Cheers,
PeteHypertensive episode associated with phenelzine and tap beer--a reanalysis of the role of pressor amines in beer.
Tailor SA, Shulman KI, Walker SE, Moss J, Gardner D.Department of Pharmacy, Sunnybrook Health Science Centre, University of Toronto, North York, Ontario, Canada.
A case report of a hypertensive crisis resulting from the ingestion of tap beer in a patient on an irreversible monamine oxidase inhibitor (MAOI; phenelzine) stimulated the investigation of different kinds of beer for tyramine concentration. The objective was to determine the tyramine concentration in tap and bottled beers. A total of 98 beer samples (79 different brands of beer) were analyzed by high-performance liquid chromatography for tyramine. Of these 98 beers, 49 were bottled or canned beers and 49 were beers on tap. All of the bottled beers analyzed had safe tyramine concentrations (< or = 10 mg/liter; range, 0 to 3.16 mg/liter) and, thus, do not require restriction in patients receiving MAOIs. Therefore, the consumption of canned or bottled beer, including dealcoholized beer, in moderation (fewer than four bottles or cans; 1.5 liters within a 4-hour period) appears to be safe and does not require restriction in patients receiving MAOIs. Only 4 of 98 beer samples studied were found to have a dangerous (> 10 mg/liter) tyramine concentration, one of which was the index beer. The tyramine concentration in these four beers ranged from 26.34 to 112.91 mg/liter. All four of these beers were tap beers produced by bottom fermentation (lagers) and brewed by a secondary fermentation process. Although we did not find any visible bacterial growth in the tap beers with high tyramine content, this finding does not preclude the possibility that bacterial contamination, bacterial growth, production of tyramine, and eventually bacterial death occurred at some earlier time. Therefore, to err on the side of caution, it is recommended that patients on irreversible MAOIs avoid beers on tap.
Posted by atypical on August 13, 2009, at 22:32:18
In reply to Nardil + Beer study, posted by pedr on August 13, 2009, at 15:07:46
Sweet. Because I love beer. I was wondering about this the other day because I got some German beer that tasted very yeasty and stuff so I traded it for my friends because I take Nardil and was a little apprehensive. I've had 6-8 drinks over the course of an evening and have not had any problems (yet, thankfully).
Posted by pedr on August 14, 2009, at 10:23:54
In reply to Re: Nardil + Beer study, posted by atypical on August 13, 2009, at 22:32:18
> Sweet. Because I love beer. I was wondering about this the other day because I got some German beer that tasted very yeasty and stuff so I traded it for my friends because I take Nardil and was a little apprehensive. I've had 6-8 drinks over the course of an evening and have not had any problems (yet, thankfully).
do you not find that that much booze makes you feel depressed? If that's the case then there is hope for my social life yet... :)
Posted by atypical on August 14, 2009, at 15:17:22
In reply to Re: Nardil + Beer study, posted by pedr on August 14, 2009, at 10:23:54
> do you not find that that much booze makes you feel depressed? If that's the case then there is hope for my social life yet... :)
Not at all. It makes me feel good! When I happen to be feeling more depressed in general, however, I do NOT drink, or I just have one drink.
Posted by AdamCanada2 on August 16, 2009, at 9:21:32
In reply to Re: Nardil + Beer study, posted by pedr on August 14, 2009, at 10:23:54
I noticed that unlike with some medications Nardil + Alcohol would make me very social and even motivated to a degree. Plus my desire to meet women would sky rocket. Although the drunk effect would take a while to come. Even after consuming a lot of alcohol I would hardly feel drunk at all. Strange isn't it.
Posted by pedr on September 15, 2009, at 13:07:45
In reply to Re: Nardil + Beer study, posted by atypical on August 14, 2009, at 15:17:22
> > do you not find that that much booze makes you feel depressed? If that's the case then there is hope for my social life yet... :)
>
> Not at all. It makes me feel good! When I happen to be feeling more depressed in general, however, I do NOT drink, or I just have one drink.
>Sorry, I wasn´t very clear. I meant the following day or day after that. I often feel very depressed on these days, hence I have (very, very sadly) given up drinking for the moment.
Posted by cybernut on March 11, 2012, at 21:12:04
In reply to Re: Nardil + Beer study » atypical, posted by pedr on September 15, 2009, at 13:07:45
> > > do you not find that that much booze makes you feel depressed? If that's the case then there is hope for my social life yet... :)
> >
> > Not at all. It makes me feel good! When I happen to be feeling more depressed in general, however, I do NOT drink, or I just have one drink.
> >
>
> Sorry, I wasn´t very clear. I meant the following day or day after that. I often feel very depressed on these days, hence I have (very, very sadly) given up drinking for the moment.I realize this is a very old thread and my MAOI is Emsam and not Nardil, but will post anyway maybe helping shed extra light. I concur with the above in that I feel much more depressed, low energy, and elevated anxiety levels when I consume bottled or canned beer of 5 or 6 bottles (more beer = worse after effects, of course) with my MAOI which is Emsam at 6mg. Also have had some bouts with mania when combining the two in large quantities (I strongly advise against that). The MAOI/alcohol relationship while not necessarily a life threatning interaction is certainly a very strange one. As such, I have also very sadly given up the alcohol part also as it isin't worth it.
Posted by cybernut on March 11, 2012, at 21:16:15
In reply to Re: Nardil + Beer study » atypical, posted by pedr on September 15, 2009, at 13:07:45
> > > do you not find that that much booze makes you feel depressed? If that's the case then there is hope for my social life yet... :)
> >
> > Not at all. It makes me feel good! When I happen to be feeling more depressed in general, however, I do NOT drink, or I just have one drink.
> >
>
> Sorry, I wasn´t very clear. I meant the following day or day after that. I often feel very depressed on these days, hence I have (very, very sadly) given up drinking for the moment.I realize this is a very old thread and my MAOI is Emsam and not Nardil, but will post anyway maybe helping shed extra light. I concur with the above in that I feel much more depressed, low energy, and elevated anxiety levels when I consume bottled or canned beer of 5 or 6 bottles (more beer = worse after effects, of course) with my MAOI which is Emsam at 6mg. Also have had some bouts with mania when combining the two in large quantities (I strongly advise against that). The MAOI/alcohol relationship while not necessarily a life threatning interaction is certainly a very strange one. As such, I have also very sadly given up the alcohol part also as it isin't worth it.
This is the end of the thread.
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