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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 19 of 19. This is the beginning of the thread.
Posted by Four Feathers on January 28, 2008, at 18:31:50
Hello Babblers! I have been lurking on this site for years and have gained very valuable information from all of you. I would appreciate any assistance you could provide.
My dx is GAD, dysthymia. My primary symptoms have been increased blood pressure and headaches along with decreased motivation,concentration, organization, and hypersomnia. I have been taking atenolol for the last 10 years to control the bp and headaches (this is especially problematic when running or other physical exertion). I am in good physical shape. I began this when I was 24 and did not realize that the underlying problem then was anxiety related. I have since been through the med merry-go-round and found limited success, often times having paradoxical reactions, and suffered the myriad of side effects. My new pdoc has hypothesized that the beta blocker may be interfering with some of the effects of the different meds that I have tried over the years for the anxiety/depr. While I know that Atenolol is one of the least lipid soluable (less likely to cross the BB barier) beta blockers, have any of you experienced problems with beta blockers, and specifically atenolol, affecting the actions of psych meds?
Posted by Justherself54 on January 29, 2008, at 8:56:28
In reply to Beta Blockers and Depression, posted by Four Feathers on January 28, 2008, at 18:31:50
> Hello Babblers! I have been lurking on this site for years and have gained very valuable information from all of you. I would appreciate any assistance you could provide.
>
> My dx is GAD, dysthymia. My primary symptoms have been increased blood pressure and headaches along with decreased motivation,concentration, organization, and hypersomnia. I have been taking atenolol for the last 10 years to control the bp and headaches (this is especially problematic when running or other physical exertion). I am in good physical shape. I began this when I was 24 and did not realize that the underlying problem then was anxiety related. I have since been through the med merry-go-round and found limited success, often times having paradoxical reactions, and suffered the myriad of side effects. My new pdoc has hypothesized that the beta blocker may be interfering with some of the effects of the different meds that I have tried over the years for the anxiety/depr. While I know that Atenolol is one of the least lipid soluable (less likely to cross the BB barier) beta blockers, have any of you experienced problems with beta blockers, and specifically atenolol, affecting the actions of psych meds?Glad you posted..I used to "lurk" too for the longest time..you'll find a wealth of information here.. I can't answer your question about beta blockers, other than I tried one years ago for my anxiety disorder, but there are lots of informed posters on babble who can..
Posted by Phillipa on January 29, 2008, at 10:21:03
In reply to Re: Beta Blockers and Depression, posted by Justherself54 on January 29, 2008, at 8:56:28
Yes welcome to babble I second the above post. I took lopressor 25mg to ready my body for an ad was the way my doc put it. It made me very tired and my pulse stayed very low when excising. I quit it after about six months. I also don't the answer to your specific question. Phillipa
Posted by Larry Hoover on January 29, 2008, at 17:36:00
In reply to Beta Blockers and Depression, posted by Four Feathers on January 28, 2008, at 18:31:50
> My new pdoc has hypothesized that the beta blocker may be interfering with some of the effects of the different meds that I have tried over the years for the anxiety/depr. While I know that Atenolol is one of the least lipid soluable (less likely to cross the BB barier) beta blockers, have any of you experienced problems with beta blockers, and specifically atenolol, affecting the actions of psych meds?
Atenolol (Tenormin) is depressogenic, and can induce emotional lability. See: http://www.rxlist.com/cgi/generic/atenolol_ad.htm under Central Nervous System in both the tables and the text descriptions. I hesitate to generalize to all beta blockers, but I am aware that propranolol is also depressogenic. Whether or not psych meds can overcome such a drug-induced depression is an academic question. It's pretty clear it didn't work for you.
If you can do without the atenolol for a period of time, why don't you see how you feel without it?
Lar
Posted by Four Feathers on January 29, 2008, at 20:42:38
In reply to Re: Beta Blockers and Depression » Four Feathers, posted by Larry Hoover on January 29, 2008, at 17:36:00
Thank you to those that have replied.
Larry, I have not tried going completely off of the Atenolol yet, but am going to try this. I have recently been going through a trial of Wellbutrin which has been overly stimulating even at the low dose of 50mg per day (only on this for a little over a week). I am going to discuss going off of the WB and then working to discontinue the Atenolol. The Atenolol has done a good job with the physical effects, but I now believe may be adding to my problem.
Thanks again!
Posted by sdb on January 31, 2008, at 9:38:06
In reply to Re: Beta Blockers and Depression, posted by Four Feathers on January 29, 2008, at 20:42:38
> Thank you to those that have replied.
>
> Larry, I have not tried going completely off of the Atenolol yet, but am going to try this. I have recently been going through a trial of Wellbutrin which has been overly stimulating even at the low dose of 50mg per day (only on this for a little over a week). I am going to discuss going off of the WB and then working to discontinue the Atenolol. The Atenolol has done a good job with the physical effects, but I now believe may be adding to my problem.
>
> Thanks again!To lower the bloodpressure there are other medications than betablockers that some people tolerate better (more compliance). For anxiety issues only a 12.5mg-25mg nadolol (isn't mebabolized which is a plus if people take more than one medication) could help but as stated does not take any anxiety feelings away. Anxiety is actually a 'normal' feeling to some degree.
There is some information I wrote quite recently:
a betablocker does not take the anxiety away. But it can be beneficial in the way that you're much more willing to provoque yourself with a certain situation. Nadolol is one betablocker with some benefits compared to propranolol. Nadolol's chemical structure is very similar to propranolol but it differs by having a hydrophile substitute. People with migraine often use nadolol as prophylaxis. It isn't metabolized by the liver and penetrates the blood-brain barrier in extremely little portions. It's half-life is 24h and there is some accumulation over some days. Maybe 10mg-40mg a day.
warm regards
sdb
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847498
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=29207655
Posted by Abby Cunningham on February 2, 2008, at 9:49:45
In reply to Re: Beta Blockers and Depression » Four Feathers, posted by Larry Hoover on January 29, 2008, at 17:36:00
Larry, I take 25mg. atenolol (my doctor calls it a "baby dose") for supraventricular tachycardia, along with verapamil SR 240mg. and have for many years.
They first put me on 50mg atenolol and I cut it in half right away on my own, and told the cardiologist when I went back; he said "OK".
eMedicine says atenolol does not cross the BBB. If that is the case how can it cause depression? Just trying to understand. And should I try the other beta blocker in such a small dose?
Thanks,
Abby
Posted by sdb on February 2, 2008, at 16:56:29
In reply to Re: Beta Blockers and Depression, posted by sdb on January 31, 2008, at 9:38:06
> > Thank you to those that have replied.
> >
> > Larry, I have not tried going completely off of the Atenolol yet, but am going to try this. I have recently been going through a trial of Wellbutrin which has been overly stimulating even at the low dose of 50mg per day (only on this for a little over a week). I am going to discuss going off of the WB and then working to discontinue the Atenolol. The Atenolol has done a good job with the physical effects, but I now believe may be adding to my problem.
> >
> > Thanks again!
>
> To lower the bloodpressure there are other medications than betablockers that some people tolerate better (more compliance). For anxiety issues only a 12.5mg-25mg nadolol (isn't mebabolized which is a plus if people take more than one medication) could help but as stated does not take any anxiety feelings away. Anxiety is actually a 'normal' feeling to some degree.
>
> There is some information I wrote quite recently:
>
> a betablocker does not take the anxiety away. But it can be beneficial in the way that you're much more willing to provoque yourself with a certain situation. Nadolol is one betablocker with some benefits compared to propranolol. Nadolol's chemical structure is very similar to propranolol but it differs by having a hydrophile substitute. People with migraine often use nadolol as prophylaxis. It isn't metabolized by the liver and penetrates the blood-brain barrier in extremely little portions. It's half-life is 24h and there is some accumulation over some days. Maybe 10mg-40mg a day.
>
> warm regards
>
> sdb
>
> http://www.ncbi.nlm.nih.gov/pubmed/6148877?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
> PMID: 6148877
>
> http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847498
> http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=29207655
>
> http://www.dr-bob.org/babble/20071225/msgs/803147.htmlbetablockers still do have its place to lower bloodpressure to a lesser degree than other meds, to lower portal hypertension, to treat arrhythmias, angina pectoris or eg. connective tissue disorders by lowering the afterload, shear stress and following dilation of some bigger blood vessels.
a PFO (a little hole in the atrial septum of the heart) could be a reason for headaches (migraine).
atenolol and nadolol are both found in the liquor cerebrospinalis. nadolol only in tiny portions. blocking brain and peripheral beta-receptors can be a reason for its depressogenic properties. It can make somebody tired, the heart contracting less vigorously. Every betablocker is somehow different , some betablockers very seldom induce depression.
Posted by Larry Hoover on February 3, 2008, at 14:46:15
In reply to Re: Beta Blockers and Depression » Larry Hoover, posted by Abby Cunningham on February 2, 2008, at 9:49:45
> eMedicine says atenolol does not cross the BBB. If that is the case how can it cause depression? Just trying to understand. And should I try the other beta blocker in such a small dose?
> Thanks,
> AbbyWell, they can say whatever they want. Way back in 1983, atenolol was shown to have central (i.e. CNS) effects in healthy volunteers. The clinical trials showed greater incidence of depression and (presumably vivid) dreaming with atenolol compared to placebo. And a recent study showed up to seven-fold higher incidence of depression (in those said to be at risk for depression) in atenolol-treated subjects compared to those on verapamil, and greater that 3-fold higher incidence in those with a history of depression.
See: http://www.psychosomaticmedicine.org/cgi/content-nw/full/67/3/398/F39
I don't know if it does or does not cross the BBB. It does have depressogenic activity, nonetheless.
You needn't switch to another drug if you're not adversely affected by it. Or, were you thinking of switching because you might be?
Lar
Posted by Phoenix1 on February 3, 2008, at 18:11:04
In reply to Re: Beta Blockers and Depression » Abby Cunningham, posted by Larry Hoover on February 3, 2008, at 14:46:15
> > eMedicine says atenolol does not cross the BBB. If that is the case how can it cause depression? Just trying to understand. And should I try the other beta blocker in such a small dose?
> > Thanks,
> > Abby
>
> Well, they can say whatever they want. Way back in 1983, atenolol was shown to have central (i.e. CNS) effects in healthy volunteers. The clinical trials showed greater incidence of depression and (presumably vivid) dreaming with atenolol compared to placebo. And a recent study showed up to seven-fold higher incidence of depression (in those said to be at risk for depression) in atenolol-treated subjects compared to those on verapamil, and greater that 3-fold higher incidence in those with a history of depression.
>
> See: http://www.psychosomaticmedicine.org/cgi/content-nw/full/67/3/398/F39
>
> I don't know if it does or does not cross the BBB. It does have depressogenic activity, nonetheless.
>
> You needn't switch to another drug if you're not adversely affected by it. Or, were you thinking of switching because you might be?
>
> Lar> > eMedicine says atenolol does not cross the BBB. If that is the case how can it cause depression? Just trying to understand. And should I try the other beta blocker in such a small dose?
> > Thanks,
> > Abby
>
> Well, they can say whatever they want. Way back in 1983, atenolol was shown to have central (i.e. CNS) effects in healthy volunteers. The clinical trials showed greater incidence of depression and (presumably vivid) dreaming with atenolol compared to placebo. And a recent study showed up to seven-fold higher incidence of depression (in those said to be at risk for depression) in atenolol-treated subjects compared to those on verapamil, and greater that 3-fold higher incidence in those with a history of depression.
>
> See: http://www.psychosomaticmedicine.org/cgi/content-nw/full/67/3/398/F39
>
> I don't know if it does or does not cross the BBB. It does have depressogenic activity, nonetheless.
>
> You needn't switch to another drug if you're not adversely affected by it. Or, were you thinking of switching because you might be?
>
> LarHi Larry,
I agree with you on beta blockers in general being depressogenic. Propanolol definitely is. But the link you posted doesn't seem to mention beta blockers, unless I missed something which is quite possible.
Other classes of antihypertensives seem OK, although I've read some anecdotal reports of ARBs being depressogenic. I think ACE inhibitors are essentially fine although the link showed a roughly 1% incidence of depression.
How about the statins? I've read some pretty controversial stuff regarding psychiatric/cognitive side effects of the statins, but millions of people are on them for hypercholesterolemia...
Anyways, interesting stuff, I'd like to hear your opinion.
Thanks,
Phoenix
Posted by Larry Hoover on February 3, 2008, at 18:46:46
In reply to Re: Beta Blockers and Depression » Larry Hoover, posted by Phoenix1 on February 3, 2008, at 18:11:04
> Hi Larry,
>
> I agree with you on beta blockers in general being depressogenic. Propanolol definitely is. But the link you posted doesn't seem to mention beta blockers, unless I missed something which is quite possible.That link didn't have a full explanation....I guess I knew what it meant.
Here's the full-text link, for which the earlier link was Figure 3 in the results section, in which they analyze the factors which influence the risk of depression for those using atenolol.
http://www.psychosomaticmedicine.org/cgi/content/full/67/3/398> Other classes of antihypertensives seem OK, although I've read some anecdotal reports of ARBs being depressogenic. I think ACE inhibitors are essentially fine although the link showed a roughly 1% incidence of depression.
>
> How about the statins? I've read some pretty controversial stuff regarding psychiatric/cognitive side effects of the statins, but millions of people are on them for hypercholesterolemia...
>
> Anyways, interesting stuff, I'd like to hear your opinion.
>
> Thanks,
>
> PhoenixI haven't looked at the other med classes. I need a little time for that.
Lar
Posted by Phillipa on February 3, 2008, at 19:58:46
In reply to Re: Beta Blockers and Depression » Phoenix1, posted by Larry Hoover on February 3, 2008, at 18:46:46
One of our babblers is having horrible reactions to statins muscles pains and other things. Phillipa
Posted by sdb on February 4, 2008, at 17:07:43
In reply to Re: Beta Blockers and Depression, posted by sdb on February 2, 2008, at 16:56:29
> > > Thank you to those that have replied.
> > >
> > > Larry, I have not tried going completely off of the Atenolol yet, but am going to try this. I have recently been going through a trial of Wellbutrin which has been overly stimulating even at the low dose of 50mg per day (only on this for a little over a week). I am going to discuss going off of the WB and then working to discontinue the Atenolol. The Atenolol has done a good job with the physical effects, but I now believe may be adding to my problem.
> > >
> > > Thanks again!
> >
> > To lower the bloodpressure there are other medications than betablockers that some people tolerate better (more compliance). For anxiety issues only a 12.5mg-25mg nadolol (isn't mebabolized which is a plus if people take more than one medication) could help but as stated does not take any anxiety feelings away. Anxiety is actually a 'normal' feeling to some degree.
> >
> > There is some information I wrote quite recently:
> >
> > a betablocker does not take the anxiety away. But it can be beneficial in the way that you're much more willing to provoque yourself with a certain situation. Nadolol is one betablocker with some benefits compared to propranolol. Nadolol's chemical structure is very similar to propranolol but it differs by having a hydrophile substitute. People with migraine often use nadolol as prophylaxis. It isn't metabolized by the liver and penetrates the blood-brain barrier in extremely little portions. It's half-life is 24h and there is some accumulation over some days. Maybe 10mg-40mg a day.
> >
> > warm regards
> >
> > sdb
> >
> > http://www.ncbi.nlm.nih.gov/pubmed/6148877?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
> > PMID: 6148877
> >
> > http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847498
> > http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=29207655
> >
> > http://www.dr-bob.org/babble/20071225/msgs/803147.html
>
> betablockers still do have its place to lower bloodpressure to a lesser degree than other meds, to lower portal hypertension, to treat arrhythmias, angina pectoris or eg. connective tissue disorders by lowering the afterload, shear stress and following dilation of some bigger blood vessels.
>
> a PFO (a little hole in the atrial septum of the heart) could be a reason for headaches (migraine).
> atenolol and nadolol are both found in the liquor cerebrospinalis. nadolol only in tiny portions. blocking brain and peripheral beta-receptors can be a reason for its depressogenic properties. It can make somebody tired, the heart contracting less vigorously. Every betablocker is somehow different , some betablockers very seldom induce depression....don't stop/withdraw the atenolol without asking your cardiologist. If you're thinking it causes depression ask for a possible alternative.
warm regards
sdb
Posted by simcha on February 4, 2008, at 19:18:44
In reply to Re: Beta Blockers and Depression » Larry Hoover, posted by Abby Cunningham on February 2, 2008, at 9:49:45
> Larry, I take 25mg. atenolol (my doctor calls it a "baby dose") for supraventricular tachycardia, along with verapamil SR 240mg. and have for many years.
>
> They first put me on 50mg atenolol and I cut it in half right away on my own, and told the cardiologist when I went back; he said "OK".
>
> eMedicine says atenolol does not cross the BBB. If that is the case how can it cause depression? Just trying to understand. And should I try the other beta blocker in such a small dose?
> Thanks,
> AbbyAbby,
I also have Supraventricular Tachycardia in the form of Ectopic Atrial Tachycardia.
I take 120mg of Sotalol 2 times per day. It's an anti-arrhythmic and beta blocker. I was given this drug by my Cardio-Electrophysiologist after two catheter ablations failed to cure the EAT. I'm chronic so I cannot stop taking my medicine or my heart rate goes up to 160-180 beats per minute.
Therefore, as someone who suffers from the same condition I advise you to go see your cardiologist or whoever prescribes you your heart medication. I know it can be dangerous to adjust this stuff on your own.
Also, I took Toprol XL 100mg (the beta blocker metoprolol) per day before the catheter ablations. And I had to discontinue it because it caused me terrible insomnia. The Cardiologist swore that Toprol XL wasn't supposed to cause this type of psychological side effect. But it did for me.
He switched me to Cardizem (a calcium channel blocker) and while it didn't control the Tachycardia very well, it didn't cause me insomnia.
The Sotalol I'm on now doesn't seem to affect me psychologically. What I know about Sotalol is that you must be in the hospital for the first three days you take it because there is a risk that it can stop your heart when you first start the medication. And I know getting off of it requires close monitoring too. Don't get on it unless you must, is my advice. I had no choice. I was in the hospital after my surgeries with a 160 bpm pulse and he had to give me the strong stuff. But at least it has no psychological side-effects for me.
Good luck!
Simcha
Posted by Abby Cunningham on February 5, 2008, at 16:26:35
In reply to Re: Beta Blockers and Depression » Abby Cunningham, posted by simcha on February 4, 2008, at 19:18:44
Thank you Simcha, for your information. Since I have been on the Verapamil + atenolol, I have had no further episodes of SVT; I used to get them where my heart rate would go to 230 and then a trip to the ER for whatever they use to bring it down (makes your whole body feel very strange); so I think I'll stick with what's working....
Best of luck to you.
Abby> Larry, I take 25mg. atenolol (my doctor calls it a "baby dose") for supraventricular tachycardia, along with verapamil SR 240mg. and have for many years.
> >
> > They first put me on 50mg atenolol and I cut it in half right away on my own, and told the cardiologist when I went back; he said "OK".
> >
> > eMedicine says atenolol does not cross the BBB. If that is the case how can it cause depression? Just trying to understand. And should I try the other beta blocker in such a small dose?
> > Thanks,
> > Abby
>
> Abby,
>
> I also have Supraventricular Tachycardia in the form of Ectopic Atrial Tachycardia.
>
> I take 120mg of Sotalol 2 times per day. It's an anti-arrhythmic and beta blocker. I was given this drug by my Cardio-Electrophysiologist after two catheter ablations failed to cure the EAT. I'm chronic so I cannot stop taking my medicine or my heart rate goes up to 160-180 beats per minute.
>
> Therefore, as someone who suffers from the same condition I advise you to go see your cardiologist or whoever prescribes you your heart medication. I know it can be dangerous to adjust this stuff on your own.
>
> Also, I took Toprol XL 100mg (the beta blocker metoprolol) per day before the catheter ablations. And I had to discontinue it because it caused me terrible insomnia. The Cardiologist swore that Toprol XL wasn't supposed to cause this type of psychological side effect. But it did for me.
>
> He switched me to Cardizem (a calcium channel blocker) and while it didn't control the Tachycardia very well, it didn't cause me insomnia.
>
> The Sotalol I'm on now doesn't seem to affect me psychologically. What I know about Sotalol is that you must be in the hospital for the first three days you take it because there is a risk that it can stop your heart when you first start the medication. And I know getting off of it requires close monitoring too. Don't get on it unless you must, is my advice. I had no choice. I was in the hospital after my surgeries with a 160 bpm pulse and he had to give me the strong stuff. But at least it has no psychological side-effects for me.
>
> Good luck!
> Simcha
Posted by KarenRB53 on July 3, 2008, at 21:05:36
In reply to Re: Beta Blockers and Depression » Phoenix1, posted by Larry Hoover on February 3, 2008, at 18:46:46
> > Hi Larry,
> >
> > I agree with you on beta blockers in general being depressogenic. Propanolol definitely is. But the link you posted doesn't seem to mention beta blockers, unless I missed something which is quite possible.
>
> That link didn't have a full explanation....I guess I knew what it meant.
>
> Here's the full-text link, for which the earlier link was Figure 3 in the results section, in which they analyze the factors which influence the risk of depression for those using atenolol.
> http://www.psychosomaticmedicine.org/cgi/content/full/67/3/398
>
> > Other classes of antihypertensives seem OK, although I've read some anecdotal reports of ARBs being depressogenic. I think ACE inhibitors are essentially fine although the link showed a roughly 1% incidence of depression.
> >
> > How about the statins? I've read some pretty controversial stuff regarding psychiatric/cognitive side effects of the statins, but millions of people are on them for hypercholesterolemia...
> >
> > Anyways, interesting stuff, I'd like to hear your opinion.
> >
> > Thanks,
> >
> > Phoenix
>
> I haven't looked at the other med classes. I need a little time for that.
>
> LarPresently I'm taking 150XL Wellbutrin and 20mg Prozac daily. I have Essential Tremor and my internist wants me to take Propranol 80mgXR daily. I'm concerned about taking these meds together and how they'll affect each other. I'd appreciate any information.
Thanks,
Karen
Posted by undopaminergic on July 4, 2008, at 12:02:59
In reply to Re: Beta Blockers and Depression » Larry Hoover, posted by KarenRB53 on July 3, 2008, at 21:05:36
>
> Presently I'm taking 150XL Wellbutrin and 20mg Prozac daily. I have Essential Tremor and my internist wants me to take Propranol 80mgXR daily. I'm concerned about taking these meds together and how they'll affect each other. I'd appreciate any information.
>
> Thanks,
> KarenI'm not aware of any specific interactions, but propranolol is somewhat risky to take if you're depressed. This is because in addition to beta1-adrenoceptors, it also blocks beta2-, and postibly beta3-adrenergic receptors, and that will result in reduced brain uptake of aromatic amino acids, including tryptophan, which is the precursor of serotonin.
Have you tried zonisamide for your essential tremor? Memantine might also he useful.
Posted by yxibow on July 11, 2008, at 1:50:27
In reply to Re: Beta Blockers and Depression, posted by undopaminergic on July 4, 2008, at 12:02:59
I've never particularly experienced any depression from propranolol. But I'm a high metabolizer and everyone is different.
I use it more PRN for odd hypertensive occasions that usually are anxiety related, up to 40-80mg.
Yes, its probably true that as a CNS depressant in part, it can cause depression. But that goes for any CNS depressant, including benzodiazepines, certain AEDs, Benadryl, etc.
Regular use of it for anxiety might impart depression in those prone to it, I would agree.
But the most important thing about beta blockers really is to have an electronic cuff (pulse/blood pressure) meter around (you can get them at most drugstores) to check your pulse and blood pressure occasionally.
Although it is non-cardioselective, nonetheless propranolol is still is a beta blocker and I think the most immediate danger is fainting (especially while operating machinery or driving) or falling from doses that produce hypotension over a long period of time.
There are as mentioned other non-cardioselective beta blockers if propranolol is not for you but propranolol has the most case history behind it for psychiatric use.-- tidings
Jay
Posted by irishcatholic on July 11, 2008, at 12:06:59
In reply to Re: Beta Blockers and Depression and Safety, posted by yxibow on July 11, 2008, at 1:50:27
bbs were bad news for me, and perhaps started the whole depression cycle IMHO
switching to diuretics + Altace (ace inhibitor) has been a good bp combo for me
been on simvastatin (generic Pravachol I believe)
for 6 mos and not seen any psych side effects and got excellent cholesterol reduction
This is the end of the thread.
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Dr. Bob is Robert Hsiung, MD,
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