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Re: Beta Blockers and Depression

Posted by sdb on January 31, 2008, at 9:38:06

In reply to Re: Beta Blockers and Depression, posted by Four Feathers on January 29, 2008, at 20:42:38

> Thank you to those that have replied.
>
> Larry, I have not tried going completely off of the Atenolol yet, but am going to try this. I have recently been going through a trial of Wellbutrin which has been overly stimulating even at the low dose of 50mg per day (only on this for a little over a week). I am going to discuss going off of the WB and then working to discontinue the Atenolol. The Atenolol has done a good job with the physical effects, but I now believe may be adding to my problem.
>
> Thanks again!

To lower the bloodpressure there are other medications than betablockers that some people tolerate better (more compliance). For anxiety issues only a 12.5mg-25mg nadolol (isn't mebabolized which is a plus if people take more than one medication) could help but as stated does not take any anxiety feelings away. Anxiety is actually a 'normal' feeling to some degree.

There is some information I wrote quite recently:

a betablocker does not take the anxiety away. But it can be beneficial in the way that you're much more willing to provoque yourself with a certain situation. Nadolol is one betablocker with some benefits compared to propranolol. Nadolol's chemical structure is very similar to propranolol but it differs by having a hydrophile substitute. People with migraine often use nadolol as prophylaxis. It isn't metabolized by the liver and penetrates the blood-brain barrier in extremely little portions. It's half-life is 24h and there is some accumulation over some days. Maybe 10mg-40mg a day.

warm regards

sdb

http://www.ncbi.nlm.nih.gov/pubmed/6148877?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
PMID: 6148877

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=7847498
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=29207655

http://www.dr-bob.org/babble/20071225/msgs/803147.html


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poster:sdb thread:809406
URL: http://www.dr-bob.org/babble/20080124/msgs/809887.html