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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by sweeperguy on November 9, 2007, at 13:32:52
HELLO NARDIL USERS
I HAVE SUCESSFULLY BEEN AT 75 MG OF NARDIL FOR RESISTANT DEPRESSION FOR 6 MONTHS AND IAM STARTING TO SLOWLY FALL BACK TO THAT BLACK HOLE . I WAS WONDERING IF ANY BODY HAD SOME ADVICE ON WHAT TO OR HAS HAD A SIMILAR EXPERIENCE TO SHARETHANK YOU AND GOD BLESS
SWEEPERGUY
Posted by kaleidoscope on November 9, 2007, at 17:00:02
In reply to NARDIL- LOOSING AFFECT AFTER 75MG, posted by sweeperguy on November 9, 2007, at 13:32:52
Hi SG
Do you have a plan? Are you going to increase the dose to 90mg?
Posted by sweeperguy on November 9, 2007, at 19:36:54
In reply to Re: NARDIL- LOOSING AFFECT AFTER 75MG » sweeperguy, posted by kaleidoscope on November 9, 2007, at 17:00:02
> Hi SG
>
> Do you have a plan? Are you going to increase the dose to 90mg?
>
>
HELLO KSCOPE
I HAVE DECIDED TO GO UP TO 90MG DO YOU THINK IT TAKES TIME TO NOTICE ANYTHING
SWEEPERGUY
Posted by kaleidoscope on November 9, 2007, at 19:40:10
In reply to Re: NARDIL- LOOSING AFFECT AFTER 75MG, posted by sweeperguy on November 9, 2007, at 19:36:54
Hi
As is the case with all antidepressants, an increased dose can take a few weeks to produce benefit. Give it a while before you decide whether it's helping.
K
Posted by Jedi on November 9, 2007, at 21:43:43
In reply to NARDIL- LOOSING AFFECT AFTER 75MG, posted by sweeperguy on November 9, 2007, at 13:32:52
> HELLO NARDIL USERS
> I HAVE SUCESSFULLY BEEN AT 75 MG OF NARDIL FOR RESISTANT DEPRESSION FOR 6 MONTHS AND IAM STARTING TO SLOWLY FALL BACK TO THAT BLACK HOLE . I WAS WONDERING IF ANY BODY HAD SOME ADVICE ON WHAT TO OR HAS HAD A SIMILAR EXPERIENCE TO SHARE
>
> THANK YOU AND GOD BLESS
> SWEEPERGUYHi,
If raising your dosage to 90mg does not help, maybe try augmentation with lithium.
Take care,
JediReference:
Title: The combination of lithium carbonate and an MAOI in refractory depressions.
Author: Fein, S : Paz, V : Rao, N : LaGrassa, J
Citation: Am-J-Psychiatry. 1988 Feb; 145(2): 249-50
Abstract: Lithium combined with phenelzine alleviated the symptoms of four severely depressed patients. Previously, all four patients had failed to respond to tricyclic antidepressants, and three had not responded to monoamine oxidase inhibitors.
Review References: None
Notes: Copyright American Psychiatric Association. Abstracts are reprinted by the permission of the publisher of the journal for volume, pages, and dates cited. Hypertext links to electronic journal sites, if available, can be found in the the Peer Reviewed Journal List on the IBIDS home page.
Language: English
Publication Type: Journal-Article
Keywords: Depressive Disorder drug therapy : Lithium therapeutic use : Phenelzine therapeutic use
URL: http://ajp.psychiatryonline.org/
Posted by UgottaHaveHope on November 10, 2007, at 4:15:54
In reply to Re: NARDIL- LOOSING AFFECT AFTER 75MG » sweeperguy, posted by Jedi on November 9, 2007, at 21:43:43
Jedi:
I dont have a subscription to that magazine. Do you know any more details of it? What dose of both meds did the people take? And how long for a response? Interesting. Thanks as always, Michael= = = = = = = = = = =
Reference:
Title: The combination of lithium carbonate and an MAOI in refractory depressions.
Author: Fein, S : Paz, V : Rao, N : LaGrassa, J
Citation: Am-J-Psychiatry. 1988 Feb; 145(2): 249-50
Abstract: Lithium combined with phenelzine alleviated the symptoms of four severely depressed patients. Previously, all four patients had failed to respond to tricyclic antidepressants, and three had not responded to monoamine oxidase inhibitors.
Review References: None
Notes: Copyright American Psychiatric Association. Abstracts are reprinted by the permission of the publisher of the journal for volume, pages, and dates cited. Hypertext links to electronic journal sites, if available, can be found in the the Peer Reviewed Journal List on the IBIDS home page.
Language: English
Publication Type: Journal-Article
Keywords: Depressive Disorder drug therapy : Lithium therapeutic use : Phenelzine therapeutic use
URL: http://ajp.psychiatryonline.org/
Posted by Jedi on November 10, 2007, at 12:13:03
In reply to Re: Details about the Nardil/Lithium study » Jedi, posted by UgottaHaveHope on November 10, 2007, at 4:15:54
> Jedi:
> I dont have a subscription to that magazine. Do you know any more details of it? What dose of both meds did the people take? And how long for a response? Interesting. Thanks as always, Michael
>
I searched the net and could not find a non-pay copy of that study. I'm sure there is a back door somewhere. Here is a link to additional abstracts using lithium and MAOIs.
Be Well,
Jedi
Posted by sweeperguy on November 10, 2007, at 13:49:46
In reply to Re: Details about the Nardil/Lithium study » UgottaHaveHope, posted by Jedi on November 10, 2007, at 12:13:03
HELLO NARDIL USERS HAVE ANY OF YOU FELT THE GOOD EFFECTS OF NARDIL SLOWILY WHEREING OFF AND GONE UP IN DOSE TO RECAPTURE ITS EFFECTS HOW LONG DOES IT TAKE TO FEEL BETTER OR DOES IT JUST POOP OUT.
THANK YOU SO MUCH FOR YOUR HELP
SWEEPERGUY
Posted by Questionmark on November 12, 2007, at 1:28:06
In reply to Re: Details about the Nardil/Lithium study, posted by sweeperguy on November 10, 2007, at 13:49:46
To be honest ive never experienced Nardil poop-out at the doses that work for me (45-60mg), thank goodness, so not sure. But i imagine a raise in dose very well might do the trick, though i would be reluctant for all obvious reasons. Make sure no other options; ask dr why it may have faded in effectiveness; then consider raising dose or augmenting it.
Posted by sweeperguy on November 12, 2007, at 6:26:37
In reply to Re: Details about the Nardil/Lithium study » sweeperguy, posted by Questionmark on November 12, 2007, at 1:28:06
> To be honest ive never experienced Nardil poop-out at the doses that work for me (45-60mg), thank goodness, so not sure. But i imagine a raise in dose very well might do the trick, though i would be reluctant for all obvious reasons. Make sure no other options; ask dr why it may have faded in effectiveness; then consider raising dose or augmenting it.
ABOUT A WEEK AGO I RAISED MY NARDIL TO 90MG TO GET THE SAME GOOD EFFECT THAT I HAD BEFORE BUT I CAN FEEL THE SIDE EFFECTS A LITTLE MORE WEIGHT GAIN IS HARD TO CONTROL, CAN NOT EJECT , INSOMNIA,
AND STIFF CRAMPING MUSSLES IN LEGS ,BUT IT STILL IS AGOOD TRADE NOT TO BE IN THE DARK
SWEEPERGUY
Posted by Jedi on November 15, 2007, at 1:58:54
In reply to Re: Details about the Nardil/Lithium study, posted by sweeperguy on November 12, 2007, at 6:26:37
> > To be honest ive never experienced Nardil poop-out at the doses that work for me (45-60mg), thank goodness, so not sure. But i imagine a raise in dose very well might do the trick, though i would be reluctant for all obvious reasons. Make sure no other options; ask dr why it may have faded in effectiveness; then consider raising dose or augmenting it.
>
> ABOUT A WEEK AGO I RAISED MY NARDIL TO 90MG TO GET THE SAME GOOD EFFECT THAT I HAD BEFORE BUT I CAN FEEL THE SIDE EFFECTS A LITTLE MORE WEIGHT GAIN IS HARD TO CONTROL, CAN NOT EJECT , INSOMNIA,
> AND STIFF CRAMPING MUSSLES IN LEGS ,BUT IT STILL IS AGOOD TRADE NOT TO BE IN THE DARK
> SWEEPERGUYHi,
I'm really the same way. I take 90mg of Nardil, plus clonazepam, plus Seroquel(25mg for sleep). I put up with a lot of side effects, but there is no side effect as bad as major depression. I believe that anyone who has been there will agree. Nardil is the only med that works for me, I've been on more than forty different combinations of different medications. Each time I have titrated off Nardil to try something newer, it has been back to the Black Hole. I'll take the side effects.
Take care,
Jedi
Posted by cee on November 17, 2007, at 12:31:07
In reply to Re: Details about Nardil » sweeperguy, posted by Jedi on November 15, 2007, at 1:58:54
> > > To be honest ive never experienced Nardil poop-out at the doses that work for me (45-60mg), thank goodness, so not sure. But i imagine a raise in dose very well might do the trick, though i would be reluctant for all obvious reasons. Make sure no other options; ask dr why it may have faded in effectiveness; then consider raising dose or augmenting it.
> >
> > ABOUT A WEEK AGO I RAISED MY NARDIL TO 90MG TO GET THE SAME GOOD EFFECT THAT I HAD BEFORE BUT I CAN FEEL THE SIDE EFFECTS A LITTLE MORE WEIGHT GAIN IS HARD TO CONTROL, CAN NOT EJECT , INSOMNIA,
> > AND STIFF CRAMPING MUSSLES IN LEGS ,BUT IT STILL IS AGOOD TRADE NOT TO BE IN THE DARK
> > SWEEPERGUY
>
> Hi,
> I'm really the same way. I take 90mg of Nardil, plus clonazepam, plus Seroquel(25mg for sleep). I put up with a lot of side effects, but there is no side effect as bad as major depression. I believe that anyone who has been there will agree. Nardil is the only med that works for me, I've been on more than forty different combinations of different medications. Each time I have titrated off Nardil to try something newer, it has been back to the Black Hole. I'll take the side effects.
> Take care,
> Jedi
>
>hello jedi
thank you for the info, it is very ineresting to meet some one who has travelled the same hard road as your self and finally found some relief after so many years of living in the dark. i would like to ask you a few questions if it is okay.
-do you have any special diet that you follow for weight gain
-do you use any vitamins
- do you get cramps in your legs
-what time of day do you take your medsi would be happy to answer any of your questions if you like
thank you
sweeperguy
Posted by Jedi on November 17, 2007, at 15:16:58
In reply to Re: Details about Nardil, posted by cee on November 17, 2007, at 12:31:07
Hi sweeperguy,
> -do you have any special diet that you follow for weight gainI really haven't been very successful with the Nardil induced weight gain. It seems to slow my metabolism plus cause the cravings for sweet carbohydrates. I do eat as many vegetables as I can and have cut out most all white foods(these seem to be the most processed).
> -do you use any vitamins
I take one multivitamin per day. Nardil can cause B6 deficiency. I take fairly high doses of Omega-3 fatty acids. 1800mg of EPA plus 1200mg of DHA. This is mostly for cardiovascular health. It does not seem to help my mood much. I also take about six heaping teaspoons of psyllium husk daily. My combination of meds gives me chronic diarrhea and the high dose of psyllium gels the bowel movement. Don't take this within a couple of hours of taking your medications as it can make your meds pass through too fast and not absorb completely.
> - do you get cramps in your legs
My legs get sore from exercise, but I rarely get cramps. The exception is if I'm working off a ladder most of the day. This causes me to tense my leg muscles and then I can get cramps at night. Does not seem to be related to the Nardil.
> -what time of day do you take your meds
I split the Nardil 45mg in the morning and 45mg at night. The clonazepam and quetiapine I take at night to help with insomnia
Take care and be well,
Jedi
Posted by FredPotter on November 17, 2007, at 17:32:46
In reply to Re: Details about Nardil » cee, posted by Jedi on November 17, 2007, at 15:16:58
A few points: Nardil and B6 react so they both cause a deficiency in the other. If I take B6 I try to make it 6 hours after my Nardil dose.
I put on weight. It's dose related and apparently nothing to do with appetite or amount eaten, so Nardil must slow the metabolism (so it makes your days seem longer!). As I'm diabetic the weight gain puts my sugars up, which I cannot allow. Sexual side effects abate on lowering the dose. I'm trying the low maintenance dose idea
Fred
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