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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by dondon on August 24, 2006, at 15:29:05
is too much acetylcholine linked to depression?
When i take anticholinergics it seems to ease my depression.
Posted by xbunny on August 24, 2006, at 16:40:11
In reply to too much acetylcholine, posted by dondon on August 24, 2006, at 15:29:05
> is too much acetylcholine linked to depression?
> When i take anticholinergics it seems to ease my depression.anticholinergics can make you feel euphoric maybe that is what is making you feel better.
Posted by linkadge on August 24, 2006, at 18:36:17
In reply to Re: too much acetylcholine, posted by xbunny on August 24, 2006, at 16:40:11
There is a theory (good theory in my opinion) that depression is due to overactive cholinergic mechanisms (relative to the monoamines). By raising the monoamines, you indirectly counteract acetylcholine. For some, direct antagonism of acetycholine can produce an antidepressant effect.
Acetylcholine is a necessary neurchemical, though stress often increases the sensitivity of the cholinergic system which can result in behavioral depression, anxiety etc.
Linakdge
Posted by Tom Twilight on August 25, 2006, at 1:20:34
In reply to Re: too much acetylcholine, posted by linkadge on August 24, 2006, at 18:36:17
Linkadge is absolutely right
An overactive Choligenic system is linked to Parkinson's disease, I think.
Anticolligenics are used for Parkinsons
Drugs that prevent the breakdown of Acetycholine like Aricept can cause depression as a side effect
This is the end of the thread.
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