![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by JahL on January 7, 2006, at 17:33:36
Just found this article which I thought some of you might find interesting:
http://news.bbc.co.uk/1/hi/health/4584866.stm
If nothing else, it gives further weight - in the mass media - to the biological model of depression.
My own pdoc knows Professor Nutt, the UK guy, well and speaks *very* highly of him as a psychopharmacologist. I was once referred to him but he was too busy. Time to ask for another referral :)
Posted by linkadge on January 7, 2006, at 19:25:29
In reply to Protein 'may' regulate depression., posted by JahL on January 7, 2006, at 17:33:36
I wonder what serotonin receptor p11 regulates?
Linkadge
Posted by Phillipa on January 7, 2006, at 21:18:04
In reply to Re: Protein 'may' regulate depression., posted by linkadge on January 7, 2006, at 19:25:29
Link, what is p ll? Fondly, Phillipa
Posted by Sarah T. on January 7, 2006, at 22:31:21
In reply to Re: Protein 'may' regulate depression., posted by linkadge on January 7, 2006, at 19:25:29
According to a news release from Rockefeller University:
"Serotonin binds to 14 different receptors on a cell's surface. One receptor in particular, known as 1B, plays a crucial role in regulating serotonin transmission in the brain. Recent studies have suggested a role for the serotonin 1B receptor in depression, as well as obsessive-compulsive disorder, drug addiction, anxiety, aggression and sleep. Intrigued by these studies, Svenningsson and colleagues at Rockefeller, the Karolinska Institute, the University of Rouen in France and Eli Lilly and Company, used a blind screen called a yeast two-hybrid screen to identify proteins that associate with the serotonin 1B receptor. They found an association with a protein called p11, a protein previously identified as a regulator of the localization of several proteins on the cell's surface."
Posted by Sarah T. on January 7, 2006, at 23:12:40
In reply to Protein 'may' regulate depression., posted by JahL on January 7, 2006, at 17:33:36
> > My own pdoc knows Professor Nutt, the UK guy, :)>>
I'm sorry, but this sentence gave me a good chuckle. Are you in the UK? Here, in the U.S., when someone is referred to as a "nut," it means they are a bit whacky.
I have come across so many physicians whose names go well with their chosen specialty. I know of a surgeon named Dr. Cutting. There was a famous neurologist named Dr. Brain. I'll try to remember a few more.
Posted by linkadge on January 8, 2006, at 8:41:35
In reply to Re: I believe it's the 1B receptor » linkadge, posted by Sarah T. on January 7, 2006, at 22:31:21
Yes, of course. Might be referring to the 5-ht1b autoreceptor.
I have wanted doctors to try and make drugs that target the 5-ht1b autoreceptor. This is one of lithium's many actions. The acute antidepressant effect of lithium may be due to 5-ht1b autoreceptor blockade.
I have wanted to see drugs that target the 5-ht1b autoreceptor like lithium without doing all the extra stuff that lithium does.
Linkadge
Posted by Tom Twilight on January 8, 2006, at 17:49:27
In reply to Protein 'may' regulate depression., posted by JahL on January 7, 2006, at 17:33:36
Hey Jahl
Were have you been all this time?
Can you turn your babblemail on?
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.