Posted by Sarah T. on January 7, 2006, at 22:31:21
In reply to Re: Protein 'may' regulate depression., posted by linkadge on January 7, 2006, at 19:25:29
According to a news release from Rockefeller University:
"Serotonin binds to 14 different receptors on a cell's surface. One receptor in particular, known as 1B, plays a crucial role in regulating serotonin transmission in the brain. Recent studies have suggested a role for the serotonin 1B receptor in depression, as well as obsessive-compulsive disorder, drug addiction, anxiety, aggression and sleep. Intrigued by these studies, Svenningsson and colleagues at Rockefeller, the Karolinska Institute, the University of Rouen in France and Eli Lilly and Company, used a blind screen called a yeast two-hybrid screen to identify proteins that associate with the serotonin 1B receptor. They found an association with a protein called p11, a protein previously identified as a regulator of the localization of several proteins on the cell's surface."
poster:Sarah T.
thread:596292
URL: http://www.dr-bob.org/babble/20051231/msgs/596388.html