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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Berberis on January 5, 2006, at 17:29:48
I'm on 500mg Depakote and want to stop it cold turkey. I'm also on 225mg Wellbutrin. Is there really any danger in not tapering the Depakote from such a low dose?
Posted by linkadge on January 5, 2006, at 18:08:51
In reply to Stopping Depakote without tapering, posted by Berberis on January 5, 2006, at 17:29:48
I personally would recommend tapering, simply due to the fact that stopping it cold turkey will temporarily lower the seizure threshold. In addition, the wellbutrin has a non-negligable potential to induce seizures.
I would reduce by 125mg every 4-5 days.
Linkadge
Posted by Phillipa on January 5, 2006, at 20:08:17
In reply to Re: Stopping Depakote without tapering, posted by linkadge on January 5, 2006, at 18:08:51
And are you replacing it with something else? Fondly, Phillipa
Posted by Berberis on January 6, 2006, at 6:49:18
In reply to Re: Stopping Depakote without tapering, posted by linkadge on January 5, 2006, at 18:08:51
Posted by Berberis on January 6, 2006, at 6:51:35
In reply to Re: Stopping Depakote without tapering, posted by Phillipa on January 5, 2006, at 20:08:17
I don't think I'll replace the Depakote with another mood stabilizer unless I start getting manic.
Posted by linkadge on January 6, 2006, at 10:37:19
In reply to Re: Stopping Depakote without tapering » Phillipa, posted by Berberis on January 6, 2006, at 6:51:35
My word is by no means the final say, but that was the first thing that came to my mind that might happen with an abrupt discontinuation.
Linkadge
Posted by blueberry on January 7, 2006, at 6:17:53
In reply to Stopping Depakote without tapering, posted by Berberis on January 5, 2006, at 17:29:48
I stopped depakote without tapering and did fine with it. Because it was the extended release version, 500mg, I really didn't have any way to taper it. I did sort of taper though...I kept spacing the doses farther apart. For example, if I took a dose in the morning one day, then I would take it in the evening the next day, so it was about 32 hours between doses instead of 24. Then after that for a week I took it just every other day for a few days and then stopped cold turkey.
I'm glad to be off of it. Except for the first two days of taking it, it did not work for me and just gave me a bunch of side effects.
This is the end of the thread.
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