![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by EERRIICC on September 8, 2005, at 18:17:22
Can you take opiates like oxycodone with MAOIs why or why not?
Posted by willyee on September 8, 2005, at 18:58:34
In reply to Opiates with MAOIs?, posted by EERRIICC on September 8, 2005, at 18:17:22
> Can you take opiates like oxycodone with MAOIs why or why not?
Technialy no,but lots of people use ultram with parnate,and chairman used one im almost postive of with no problems.
Reason why,i think it comes down to the ole serotoinin syndrome thing again.
Although some have been taken with parnate,i know fou sure some really cant,personaly i almost had a reaction using a small dose of ultram,i quickly gave the supply away,i did not like what i felt,and lord knows i have played russion rolette with parnate.
Chairman will probuably reply in more detail for ya.
Posted by Chairman_MAO on September 8, 2005, at 23:37:04
In reply to Re: Opiates with MAOIs?, posted by willyee on September 8, 2005, at 18:58:34
You can use any opiate/opioid as long as it does not have significant serotonergic activity. The big no-no opioid is demerol/meperidine/pethidine; under no circumstances should that be used concomitantly with an MAOI. Ultram is sketchy; not as bad as demerol, but it is a demerol analogue nonetheless and I would avoid it.
DXM, while devoid of opioid agonist activity, I should mention also has serotonin releasing action and thus cannot be taken with an MAOI.
I personally have used heroin and buprenorphine while on tranylcypromine, and buprenorphine on phenelzine with no ill effects whatsoever. High-dose tranylcypromine is especially ideal for those on opioids because it mitigates the sedation they can cause, if that is desired.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.