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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 10 to 34 of 34. Go back in thread:
Posted by ed_uk on May 6, 2005, at 5:45:06
In reply to Re: Concerta - when does it hit ? » stresser, posted by theo on May 5, 2005, at 21:21:35
Hi!
What withdrawal symptoms are you having from Concerta??
Ed.
Posted by theo on May 6, 2005, at 12:11:42
In reply to Re: Concerta - when does it hit ? » theo, posted by ed_uk on May 6, 2005, at 5:45:06
> Hi!
>
> What withdrawal symptoms are you having from Concerta??
>
> Ed.Just what I mentioned above, agitation and maybe a little depression, nothing horrible at all.
Posted by stresser on May 6, 2005, at 22:36:57
In reply to Re: Concerta - when does it hit ? » stresser, posted by theo on May 5, 2005, at 21:21:35
Why are you not taking the concerta any longer? You may have told me before, but I don't remember. Are you willing to try something different? -L
Posted by theo on May 8, 2005, at 10:31:11
In reply to Re: Concerta - when does it hit ? » theo, posted by stresser on May 6, 2005, at 22:36:57
> Why are you not taking the concerta any longer? You may have told me before, but I don't remember. Are you willing to try something different? -L
The Concerta worked okay in some areas but I just didn't see myself taking it monotherapy long term. Although it is smooth, it does wear off and being the only med I was taking, I need to find something else for my other symptoms and maybe add that back as an add on.
I didn't have a negative experience at all, and just want to try some other options (besides stims) for long term use. I don't want to age prematurely from speeding my body up every day. It's got to catch up in the long run. What do you think, does that thought ever concern you?
Posted by cybercafe on May 9, 2005, at 6:06:39
In reply to Re: Concerta - when does it hit ? » stresser, posted by theo on May 8, 2005, at 10:31:11
Posted by pro_social_soon on May 9, 2005, at 9:14:47
In reply to Anyone notice an effect on libido ? (nm), posted by cybercafe on May 9, 2005, at 6:06:39
Yeah much much lower. Pretty much like on SSRI.
Posted by alohashirt on May 9, 2005, at 22:13:13
In reply to Re: Concerta - when does it hit ? » stresser, posted by theo on May 8, 2005, at 10:31:11
I spent a year working in a needle exchange in Europe and came away with a clear impression that many opiate addicts had skin that looked younger than their real age. This seemed surprising given the hard work they were frequently doing to pay for their daily dose. Is it conceivable that stimulants cause aging?
> I didn't have a negative experience at all, and just want to try some other options (besides stims) for long term use. I don't want to age prematurely from speeding my body up every day. It's got to catch up in the long run. What do you think, does that thought ever concern you?
>
Posted by Declan on May 9, 2005, at 22:57:13
In reply to Aging speed up or slow down with meds, posted by alohashirt on May 9, 2005, at 22:13:13
This is often said about opiate users who also often say that while on opiates their health was better than it became when they gave up. This effect is undermined by the relative toxicity of both methadone and injected , poorly prepared impure heroin. Stimulants would surely have to be harder on you than opiates properly taken.
Declan
Posted by theo on May 9, 2005, at 23:02:17
In reply to Aging speed up or slow down with meds, posted by alohashirt on May 9, 2005, at 22:13:13
> I spent a year working in a needle exchange in Europe and came away with a clear impression that many opiate addicts had skin that looked younger than their real age. This seemed surprising given the hard work they were frequently doing to pay for their daily dose. Is it conceivable that stimulants cause aging?
>
> > I didn't have a negative experience at all, and just want to try some other options (besides stims) for long term use. I don't want to age prematurely from speeding my body up every day. It's got to catch up in the long run. What do you think, does that thought ever concern you?
> >
>
>I really haven't looked into it, but adding a central nervous system stimulant to your body daily seems harsh, just my perception. I know after stopping Concerta, I felt like I had been to a three day blow out. I didn't feel that way while taking it, but seems my body was working overtime from the daily stimulation and I definitely realize that looking back.
Posted by ed_uk on May 10, 2005, at 5:29:48
In reply to Re: Aging speed up or slow down with meds, posted by Declan on May 9, 2005, at 22:57:13
Hi,
I think you said you were taking methadone 1.25mg. I think you also mentioned that you are not satisfied with methadone. Have you considered switching to buprenorphine or controlled-release morphine?
I'm sure you are knowledgable about buprenorphine. Here is some information about controlled-release morphine.......
Addiction. 2004 Aug;99(8):940-5.
Slow-release oral morphine versus methadone: a crossover comparison of patient outcomes and acceptability as maintenance pharmacotherapies for opioid dependence.Mitchell TB, White JM, Somogyi AA, Bochner F.
Department of Clinical and Experimental Pharmacology, University of Adelaide, Adelaide, South Australia, 5005, Australia. t.mitchell@iop.kcl.ac.uk
AIMS: To evaluate slow-release oral morphine (SROM) as an alternative maintenance pharmacotherapy to methadone for treatment of opioid dependence. DESIGN: Open-label crossover study. SETTING: Out-patient methadone maintenance programme. PARTICIPANTS: Eighteen methadone maintenance patients. Intervention Participants were transferred from methadone to SROM (once-daily Kapanol trade mark ) for approximately 6 weeks before resuming methadone maintenance. MEASUREMENTS: Patient outcomes were assessed (1) during the transition between medications (dose requirements, withdrawal severity) and (2) after at least 4 weeks on a stable dose of each drug (treatment preference, patient ratings of treatment efficacy and acceptability, drug use, health, depression and sleep). FINDINGS: Transfer from methadone to SROM was associated with relatively mild withdrawal for the first 5 days; the final mean SROM : methadone dose ratio was 4.6 : 1. Compared to methadone, SROM was associated with improved social functioning, weight loss, fewer and less troublesome side-effects, greater drug liking, reduced heroin craving, an enhanced sense of feeling 'normal' and similar outcomes for unsanctioned drug use, depression and health. The majority of subjects preferred SROM (78%) over methadone (22%). CONCLUSIONS: These findings provide justification for further evaluation of SROM as a maintenance pharmacotherapy for opioid dependence.
Kind regards,
Ed.
Posted by stresser on May 10, 2005, at 13:32:44
In reply to Opioids » Declan, posted by ed_uk on May 10, 2005, at 5:29:48
After reading the previous posts, I am getting a bit nervous about taking medication for ADD. I didn't realise that it ages your body faster, or is that not true? I am finding that the Adderall XR is working well for me, but I don't want to continue to take it if it is going to age my body faster than normal. -L
Posted by theo on May 10, 2005, at 14:58:12
In reply to Nervous about Concerta/Adderall, posted by stresser on May 10, 2005, at 13:32:44
> After reading the previous posts, I am getting a bit nervous about taking medication for ADD. I didn't realise that it ages your body faster, or is that not true? I am finding that the Adderall XR is working well for me, but I don't want to continue to take it if it is going to age my body faster than normal. -L
It just seems logical, but may not be true. I do know I've had some horrible nervous anxiety since stopping Concerta a week ago. I was just taking 18mg, so there is really no smaller dose to taper to. It's weird, it's kind of like a long term crash that I didn't expect coming off such a small dose. I am going to try a low dose of Depakote ER starting tonight, so maybe that will put the brakes on this med induced anxiety.
Posted by stresser on May 11, 2005, at 18:28:15
In reply to Re: Nervous about Concerta/Adderall » stresser, posted by theo on May 10, 2005, at 14:58:12
Good luck with that. Let me know how that works for you. -L
Posted by theo on May 11, 2005, at 23:13:38
In reply to Re: Nervous about Concerta/Adderall » theo, posted by stresser on May 11, 2005, at 18:28:15
How's the Adderall XR treating you? I'm sure my curiousity is going to get the best of me and I'll end up trying it.
The Depakote ER is going okay I guess. I don't really feel I'm taking anything, just a little mellow. I could definitely see taking this low dose and adding something activating back in. Since Depakote is good for headaches, maybe if I tried another stim it would help with the headaches?
Posted by cybercafe on May 12, 2005, at 2:07:01
In reply to Re: Anyone notice an effect on libido ? » cybercafe, posted by pro_social_soon on May 9, 2005, at 9:14:47
> Yeah much much lower. Pretty much like on SSRI.
>Uh... when it wears off (esp the short acting versions) does the libido come back ??
Posted by cybercafe on May 12, 2005, at 2:09:54
In reply to Re: Aging speed up or slow down with meds » alohashirt, posted by theo on May 9, 2005, at 23:02:17
> > I spent a year working in a needle exchange in Europe and came away with a clear impression that many opiate addicts had skin that looked younger than their real age. This seemed surprising given the hard work they were frequently doing to pay for their daily dose. Is it conceivable that stimulants cause aging?
> >
> > > I didn't have a negative experience at all, and just want to try some other options (besides stims) for long term use. I don't want to age prematurely from speeding my body up every day. It's got to catch up in the long run. What do you think, does that thought ever concern you?
> > >
> >
> >
>
> I really haven't looked into it, but adding a central nervous system stimulant to your body daily seems harsh, just my perception. I know after stopping Concerta, I felt like I had been to a three day blow out. I didn't feel that way while taking it, but seems my body was working overtime from the daily stimulation and I definitely realize that looking back.
>
>
>
>I was told that cocaine works by causing an adrenalin rush, which alters blood flow to skin and nerve stimulation to muscles around the face, altering the normal look and shape.
Now with ritalin, I worry about things from a more hormonal level -- I believe it lowers testosterone and growth hormone, to what degree I'm not sure, and I wonder what effects these would have long term.
Posted by stresser on May 12, 2005, at 15:25:48
In reply to Re: Nervous about Concerta/Adderall » stresser, posted by theo on May 11, 2005, at 23:13:38
Adderall is ok, so far! My concentration is improving and I hope it stays that way, or at least doesn't go the opposite direction. I think trying it won't be as bad as you think it will be. -L
Posted by theo on May 12, 2005, at 16:35:13
In reply to Re: Nervous about Concerta/Adderall » theo, posted by stresser on May 12, 2005, at 15:25:48
I forgot, are you taking 20mg XR?
Posted by stresser on May 13, 2005, at 11:47:28
In reply to Re: Nervous about Concerta/Adderall » stresser, posted by theo on May 12, 2005, at 16:35:13
Yes, 20mg of the XR. -L
Posted by Declan on May 14, 2005, at 21:02:03
In reply to Opioids » Declan, posted by ed_uk on May 10, 2005, at 5:29:48
It would be nice wouldn't it Ed. And more compliance with the idea of the program. Interestingly there ia an Australian doctor who advocated getting round the whole heroin/voodoo thing by having a hydromorphone program. Then the Tasmanian poppy farmers won't feel so threatened by US sponsored WHO removal of their right to produce.
Declan
Posted by ed_uk on May 15, 2005, at 7:43:56
In reply to Opioids » Declan, posted by ed_uk on May 10, 2005, at 5:29:48
Hi,
So you can't try buprenorphine? It's prescribed a lot in England... just as much as methadone.
Ed.
Posted by university on May 16, 2005, at 0:37:30
In reply to Re: Anyone notice an effect on libido ?, posted by cybercafe on May 12, 2005, at 2:07:01
> > Yeah much much lower. Pretty much like on SSRI.
> >
>
> Uh... when it wears off (esp the short acting versions) does the libido come back ??With me, Ritalin (Concerta) *increased* my libido. However, I'm pretty sure it causes me a certain amount of...er...flaccidity if you know what I mean.
Posted by Paulbwell on May 17, 2005, at 8:48:32
In reply to Re: Opioids.... to Declan, posted by ed_uk on May 15, 2005, at 7:43:56
> Hi,
>
> So you can't try buprenorphine? It's prescribed a lot in England... just as much as methadone.
>
> Ed.is it available in tabs? downunder only the injectable is available now.
Posted by ed_uk on May 17, 2005, at 9:41:31
In reply to Re: Opioids.... to Declan » ed_uk, posted by Paulbwell on May 17, 2005, at 8:48:32
Hi,
In England, buprenorphine is available as sublingual tablets (Temgesic and Subutex): 200mcg, 400mcg, 2mg and 8mg.
It comes as an injection solution (Temgesic): 300mcg/mL, 1mL amp.
It's also available as a 72 hour skin patch (Transtec): 35mcg/hour, 52.5mcg/hour and 70mcg/hour.
Regards,
Ed.
Posted by Declan on May 17, 2005, at 15:00:12
In reply to Re: Opioids.... to Declan » Paulbwell, posted by ed_uk on May 17, 2005, at 9:41:31
In the clinics they use sublingual tabs
This is the end of the thread.
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