![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by rod on September 27, 2004, at 5:16:53
Hi,
I am thinking about trying Celebrex (celecoxib) to augment antidepressive treatment.
I can only find very little information about its effect on the CNS. Does anybody know what it is doing apart its anti-inflamatory effect? what about dopamine, serotonin, noradrenaline?the most useful info I found is:
"COX-2 inhibitors as adjunctive therapy in schizophrenia"
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15268640"..From a theoretical point of view, other psychiatric indications for selective COX-2 inhibitors are discussed.."
the full article would be interesting....
thanks
Roland
Posted by SLS on September 27, 2004, at 7:21:39
In reply to How does CELEBREX work for depression?, posted by rod on September 27, 2004, at 5:16:53
Hi Roland.
I've seen this abstract, and without reading the full text, it would seem that inappropriate inflammatory processes themselves can have wide-reaching effects within the human body. Perhaps inflammation is the key to this drug's beneficial effect afterall.
- Scott
Posted by Sad Panda on September 27, 2004, at 10:43:07
In reply to How does CELEBREX work for depression?, posted by rod on September 27, 2004, at 5:16:53
> Hi,
>
> I am thinking about trying Celebrex (celecoxib) to augment antidepressive treatment.
> I can only find very little information about its effect on the CNS. Does anybody know what it is doing apart its anti-inflamatory effect? what about dopamine, serotonin, noradrenaline?
>
> the most useful info I found is:
> "COX-2 inhibitors as adjunctive therapy in schizophrenia"
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15268640
>
> "..From a theoretical point of view, other psychiatric indications for selective COX-2 inhibitors are discussed.."
>
> the full article would be interesting....
>
> thanks
> Roland
>A couple of months ago I switched from Voltaren to Celebrex for my knees. I can't say I noticed anything psychotropical about it. I have 200mg capsules and take one per day most days.
Cheers,
Paul.
Posted by linkadge on September 27, 2004, at 21:44:20
In reply to Re: How does CELEBREX work for depression? » rod, posted by Sad Panda on September 27, 2004, at 10:43:07
I have noticed at times that when I was extremely suicidal, popping 2 advil really seemed to tame down that sickening feeling.
Linkadge
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.