Psycho-Babble Medication Thread 354447

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Marplan - please compare with Nardil or Parnate

Posted by don_bristol on June 7, 2004, at 7:11:36

I have taken Nardil and found it too sedating as it gave me too much of a "fog".

I have recently started Parnate which I find energising but it has yet to work on my mood

A post here suggested that Marplan was the drug of choice out of the MAOIs. Marplan is available here in the UK so it is an option.

What is Marplan like compared to Parnate and Nardil?

 

Re: Marplan - please compare with Nardil or Parnate

Posted by King Vultan on June 7, 2004, at 12:35:05

In reply to Marplan - please compare with Nardil or Parnate, posted by don_bristol on June 7, 2004, at 7:11:36

> I have taken Nardil and found it too sedating as it gave me too much of a "fog".
>
> I have recently started Parnate which I find energising but it has yet to work on my mood
>
> A post here suggested that Marplan was the drug of choice out of the MAOIs. Marplan is available here in the UK so it is an option.
>
> What is Marplan like compared to Parnate and Nardil?


http://www.vh.org/adult/provider/psychiatry/CPS/19.html

Table 3 has some comparisons between the three MAOIs. Unfortunately, it does list Marplan as more sedating than Nardil; however, this is only one perspective and may not tally with some users' experience. I would expect Nardil and Marplan to be more similar to each other than either would be to Parnate, as both Nardil and Marplan are hydrazine derivatives (this is why both are listed as 5's for hepatotoxicity, but keep in mind that this is a relatively rare side effect). Parnate, OTOH, has a more amphetamine-like structure, is more dopaminergic, and more stimulating.

Todd

 

Re: Marplan - please compare with Nardil or Parnate » don_bristol

Posted by teknohead on June 7, 2004, at 18:54:39

In reply to Marplan - please compare with Nardil or Parnate, posted by don_bristol on June 7, 2004, at 7:11:36

How long did you take Nardil for and for what reason?

I've only taken Nardil. I take it for Social Phobia with associated depression. It has worked wonders!

I had many side effects, one of which was a 'very' foggy head, and sedation.

The side effects took a good 3 months to go, including the head fog, but it 'does' go. I still get sedation but I've learnt a way to manage it. I take 90mg. When I start to feel sedated, normally whilst doing something like reading or watching TV, this is normally the first indication of several days of it. So I reduce my dose to 75mg, or sometimes 60mg. This should be enough to get rid of all sedation. I stay on this dose for up to 5 days and then return to 90mg (5 days shouldn't reduce the effectiveness of the Nardil). Doing this seems to cut out most sedation for a good 2 weeks or more. Then I just repeat the process. Easy. And as a bonus, when returning to 90mg, I often have a return of the euphoria I had when the Nardil first kicked in! Enjoyable, but certainly NOT hypomanic.

I know we're all different, and that what works for one may not work for another. But Nardil really can work wonders if you give it a real good chance.



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