Psycho-Babble Medication Thread 336205

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Re: ATTN Scotty SLS

Posted by ace on April 20, 2004, at 1:55:08

In reply to Re: ATTN Scotty, posted by SLS on April 19, 2004, at 6:45:26

> > Hi Andrew.
> >
> >
> > > Thanks so much Scott. I really appreciate your reply and insights.
> >
> > Just don't forget about Risperdal. I have a good feeling about this drug for you. No guarantees, of course.
> >
> > > How are you doing yourself mate?
> >
> > I've been worse.
> >
> > :-)
> >
> > You'll get there. 100%
> >
> >
> > - Scott
>
>
> Just a thought.
>
> Since there is no guarantee that Risperdal will do the trick, and you do recieve benefit from Zyprexa, it might be a reasonable strategy to try the other atypical neuroleptics as well. I would keep the Zyprexa at 5-10mg and test each drug as an add-on in the sequence you feel makes sense.
>
> - Scott
>

Thanks mate. I will do exactly this...you know me- I wont stop until i get remmision!

Andrew (Ace)

 

Re: Must I stop my beloved Nardil????? SLS

Posted by ace on April 20, 2004, at 1:57:19

In reply to Re: Must I stop my beloved Nardil?????, posted by SLS on April 19, 2004, at 14:27:02

> > Hi Ace,
> >
> > Have you tried some SSRI's, Effexor or Clomipramine?
>
>
> Yeah, Ace. It has been awhile since you listed all the things you have tried. I have been assuming that you've tried all of these drugs already.

Preety much. But sometimes I have bailed out a little too early (no patience!)...I will generate a list soon. And yes, I think Risperidone I will trial...thanks for the support bro! You rule!

Ace

>
>
> - Scott

 

Re: ATTN Scotty SLS

Posted by ace on April 20, 2004, at 1:58:53

In reply to Re: ATTN Scotty, posted by SLS on April 19, 2004, at 10:10:36

Scotty,
I forgot to ask...you are on the "Californian rocket fule" combo arent you???

If so, I hope you get 110% remission brother!

Your mate,
Andrew
(Ace)

 

Re: ATTN Scotty ace

Posted by SLS on April 20, 2004, at 6:35:46

In reply to Re: ATTN Scotty SLS, posted by ace on April 20, 2004, at 1:55:08

Hi buddy.

> > > Just don't forget about risperidone. I have a good feeling about this drug for you. No guarantees, of course.

> Thanks mate. I will do exactly this...you know me- I wont stop until i get remmision!

I know how hard it is to be patient. I myself have tended to be reactionary to anything that does not get me better quickly and has negative initial side effects. I know how easy it is to want to bail-out on a drug. I bring this up because risperidone might not feel like the right drug for you during the first week or two. In fact, you *might* feel that it makes you feel slowed-down and somewhat depressed. This usually dissipates in about a week, hopefully leaving you a future of gradual improvement. Other side effects that can occur during the first couple of weeks include mild to moderate anxiety, sedation, and dry mouth, and perhaps dizziness. Try to avoid the temptation to load up on risperidone right away. I would start out with 0.50mg a day and raise it by 0.50 every week or every two weeks to a maximum of perhaps 3.0mg. This is a moderate dosage that is commonly thought to have very little risk of developing TD. Supposedly, the threshold of increased risk is 6.0mg.

As I mentioned in a previous post, risperidone has been known to induce OCD or make it worse. However, this same phenomenon has been seen with other neuroleptics, including olanzapine. Risperidone is the most potent 5-HT2a antagonist of the neuroleptics. This action is probably a positive therapeutic attribute for some people with refractory OCD and perhaps a negative property for others. Just remember, you are not married to this drug. You can stop it anytime you want. I urge you to give it a thorough trial, and know that you are making an informed decision. I think the risk of some temporary discomfort is worth the potential benefits that risperidone offers you. If it makes your OCD dramatically worse, just discontinue it as you have other drugs to which you reacted negatively. Otherwise, try to stick it out for the first few weeks. I'll keep my fingers crossed for you. Risperidone has worked wonders for some people with refractory OCD. Keep the olanzapine for now.

Good luck!


- Scott


 

Re: ATTN Scotty ace

Posted by SLS on April 20, 2004, at 6:41:09

In reply to Re: ATTN Scotty SLS, posted by ace on April 20, 2004, at 1:58:53

> Scotty,

Scott :-)

> I forgot to ask...you are on the "Californian rocket fule" combo arent you???

I tried combining Remeron with Effexor 300mg, but the addition of Remeron made me feel moderately worse. I once reacted badly to a similar drug, idazoxan. It was worth the risk, though. I am trying to leave no stone unturned.


- Scott

 

Re: ATTN Scotty

Posted by Sad Panda on April 20, 2004, at 9:34:34

In reply to Re: ATTN Scotty ace, posted by SLS on April 20, 2004, at 6:41:09

> > Scotty,
>
> Scott :-)
>
> > I forgot to ask...you are on the "Californian rocket fule" combo arent you???
>
> I tried combining Remeron with Effexor 300mg, but the addition of Remeron made me feel moderately worse. I once reacted badly to a similar drug, idazoxan. It was worth the risk, though. I am trying to leave no stone unturned.
>
>
> - Scott
>

How much Remeron were you taking? I had a bad time trying to tritate from 15mg to 30mg, Alpha-2 blockade just causes me severe irritation & crankiness. I still think of it as a good sleep pill that counters SSRI type side effects & people should only take as much as they need, rather than high dose as it is just not an effective AD for most people. I think it would be a better pill if it didn't have Alpha-2 antagonism because the 5-HT2A, 5-HT2C & 5-HT3 antagonism is great.

Cheers,
Panda.

 

Re: Must I stop my beloved Nardil????? ace

Posted by Sad Panda on April 20, 2004, at 9:56:05

In reply to Re: Must I stop my beloved Nardil????? Sad Panda, posted by ace on April 20, 2004, at 1:53:43

> > Hi Ace,
> >
> > Have you tried some SSRI's, Effexor or Clomipramine?
>
> Yes. Zoloft was rubbish. Luvox I only lasted two days on. Anafranil I have tried 3 times. Each time i cant make it past the third day. First time, I wanted no drugs so I stopped it. SAecond time it worsened my derealization. third time it worsened my depression
>
> But I may try it again (probably will) in the future!
>
> >
> > I take it that social anxiety is a much bigger problem for you compared to OCD?
>
> Absolutely not. My huge two problems are OCD and phobic anxiety of depersonalization syndrome. I hate labels: overall i am a very anxious person getting caught up in obsessive thoughts. Nardil is THE drug for phobic anxiety, but works great for my dysthmia and depression too.
>
>

Ooohh, I thought you had social anxiety, I don't know how I got that stuck in my head. Everything I have tried to read & absorb says you have to have an SRI to counter OCD. Patience is good to have, when I have raised the dosage of Effexor it causes me tons of anxiety in the first week or so, taking some Valium seems to take the anxiety away & leave me with some mild hypomania(overly talkative & unrealisticly good mood), after a couple of weeks I settle in an I get some good anxiolytic effect from it. I use to have a little OCD ritual before bed of going to the front door, checking that it's locked, turn power off to TV & PayTV box at wall, go to back door & check that it's locked & then head to the front door & repeat about 3-4 times before finally going to bed.(This use to drive my wife nuts!) When I was spiralling into depression & having suicide ideations countinuosly my door checking ritual was climbing upwards too. Now, with Effexor, I only do the ritual just once. If you haven't tried Effexor, I would, you just have to be prepared for possible withdrawl symptoms & have Valium onhand to counter any startup anxiety.

Cheers,
Panda.

 

Re: ATTN Scotty Sad Panda

Posted by SLS on April 20, 2004, at 10:18:56

In reply to Re: ATTN Scotty, posted by Sad Panda on April 20, 2004, at 9:34:34

> > I tried combining Remeron with Effexor 300mg, but the addition of Remeron made me feel moderately worse. I once reacted badly to a similar drug, idazoxan. It was worth the risk, though. I am trying to leave no stone unturned.

> How much Remeron were you taking? I had a bad time trying to tritate from 15mg to 30mg, Alpha-2 blockade just causes me severe irritation & crankiness. I still think of it as a good sleep pill that counters SSRI type side effects & people should only take as much as they need, rather than high dose as it is just not an effective AD for most people. I think it would be a better pill if it didn't have Alpha-2 antagonism because the 5-HT2A, 5-HT2C & 5-HT3 antagonism is great.

I think I only made it up to 30mg. It worsened my depression at that dosage. Idazoxan is an experimental compound known to be a potent NE alpha2 antagonist. It made me feel much worse for the many weeks I was on it. I wasn't surprised when Remeron did so too.

Have you thought to try Serzone?


- Scott

 

Re: ATTN Scotty SLS

Posted by Sad Panda on April 20, 2004, at 10:30:10

In reply to Re: ATTN Scotty Sad Panda, posted by SLS on April 20, 2004, at 10:18:56

>
> I think I only made it up to 30mg. It worsened my depression at that dosage. Idazoxan is an experimental compound known to be a potent NE alpha2 antagonist. It made me feel much worse for the many weeks I was on it. I wasn't surprised when Remeron did so too.
>
> Have you thought to try Serzone?
>
>
> - Scott
>
>

Serzone? Did I tell you about my phobia of priapism which requires surgery to reverse? :) My understanding is it's only a 5-HT2A blocker & you get that for free in most TCA's & Remeron (& lots of AP's) Without Remeron & on Effexor only I had nausea that just never seem to go away, just 15mg got rid of my nausea totally. I really don't think I could take Effexor without Remeron, they should come mixed together at a ratio of 10:1 for me. :)

Cheers,
Panda.


 

Re: Must I stop my beloved Nardil????? ace

Posted by luther on April 21, 2004, at 3:14:06

In reply to Must I stop my beloved Nardil?????, posted by ace on April 14, 2004, at 2:11:37

Hey Ace,
I've heard people talking about Adderall. No one is more upset that Pfizer could change Nardil, the only thing that worked for my SAD, GAD and Atypical Depression. It saved my life many years ago, now I'm back at the point where I first began, in the gutter. You might try Neurontin also.

 

Re: Must I stop my beloved Nardil?????

Posted by bobbiedobbs on May 3, 2004, at 13:44:44

In reply to Must I stop my beloved Nardil?????, posted by ace on April 14, 2004, at 2:11:37

I am very interested in knowing the best you've gone up with since the initial post - I am a long-time Nardil user who switched to Lexapro, then luvox, after the Nardil stopped working. None of these help and all exhaust me. My problems are social anxiety/generalized anxiety plus OCD. The OCD needs to be treated but the social/GAD is disenabling re work, former friends, virtually any outside contact.
Looking for best post-Nardil med suggestions with tolerable fatigue, minimal loss of cognitive/memory/loss f function, weight gain, sexual sides - in short for the right word, functions - in short, everything(actually, just a little something to help).
Contemplating: Marplan, Zoloft (zzz?), Effexor. Anyone psychopharmaceutically (sp?) inclined might advise me what the Nardil surpressed so I can look for that in other meds -
Would especially like to hear from Ace/Panda/Chemist (sounds like the Architect in the Matrix)
MUCH appreciated.
Phil

 

Re: Must I stop my beloved Nardil????? bobbiedobbs

Posted by harryp on May 4, 2004, at 4:05:50

In reply to Re: Must I stop my beloved Nardil?????, posted by bobbiedobbs on May 3, 2004, at 13:44:44

You didn't mention Parnate. Have you tried that? For me, it was the first and only AD that not only worked, but had no bad effects on my cognitive or creative abilities (or anything else, for that matter!).

 

Re: Must I stop my beloved Nardil????? harryp

Posted by bobbiedobbs on May 4, 2004, at 11:51:02

In reply to Re: Must I stop my beloved Nardil????? bobbiedobbs, posted by harryp on May 4, 2004, at 4:05:50

Actually, I did try Parnate. It was definately the most benign of everything I tried re side effects. If all else fails I probably will go back to it. It took the edge off of my social anxiety in terms of gut wrenching worry but I was still pretty avoidant and generally reticent.

 

Re: Must I stop my beloved Nardil?????

Posted by platinumbride on May 5, 2004, at 13:55:56

In reply to Re: Must I stop my beloved Nardil????? Sad Panda, posted by ace on April 20, 2004, at 1:53:43

Have you tried neurontin? I have heard of it helping OCD and I believe that it has relatively few contraindications.

Best to you,

Diane

 

Re: Must I stop my beloved Nardil????? platinumbride

Posted by luther on May 6, 2004, at 18:27:35

In reply to Re: Must I stop my beloved Nardil?????, posted by platinumbride on May 5, 2004, at 13:55:56

I'm taking Neurontin as well, 100mg TID and new "bad" Nardil 30mg TID and Valium 15mg TID. I've had the strangest experiences with the new Nardil. After changing from the old to the new I had all the classic withdraw symptoms and it stopped working as if I were taking a placebo. Then I changed to Parnate which I knew never worked that well and it didn't this time either. Then I changed back to the new Nardil and it worked about 50% and my libido came back over 100% and then I added Neurontin again and didn't have the need to sleep and would stay up 24 hours at a time. After 2 weeks this ended, the sexual dysfunction came back, but not as bad as with the old Nardil. Nardil still was working maybe 50% as well as the old. Now I'm not doing well at all, 3 months after going back to Nardil. My anxiety has returned to the point that I can't type or write as well and I have restless leg syndrome that I had prior to starting Nardil in 93. When I first started taking it back then with Valium it was a dream come true or a miracle, my GAD, SAD and Atypical Depression disappeared. This after wasting 3 years of Tricyclic and SSRI use that was a waste of money and time. I really hope we can do something about what Pfizer has done to us! I'm sure they are well aware of it, even if the act naive about the whole situation. Why would they move production to France? To avoid the FDA? How can I trust the FDA when they approve SSRI's for Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)? The side effects of SSRI's are anxiety, lol! Pharmaceutical companies donated billions of $$$ to the last presidential election for fear of government price controls. I really hope we can do something about what Pfizer has done, taken our lives away! Where is the Uni-bomber, that Ted fellow? I'm only kidding, I don't want a black Ford sedan in front of my place. Has anyone tried Marplan? Everyone take care, I know this is one big struggle! Feel free to write me.
Sincerely,
Brian
luthermeeks@peoplepc.com

> Have you tried neurontin? I have heard of it helping OCD and I believe that it has relatively few contraindications.
>
> Best to you,
>
> Diane

 

New Nardil problems

Posted by harryp on May 6, 2004, at 19:16:16

In reply to Re: Must I stop my beloved Nardil????? platinumbride, posted by luther on May 6, 2004, at 18:27:35

I'm sure glad that I take Parnate and not Nardil. I've been very puzzled as to why the "new Nardil" has caused so many problems for people.

I can see that a new binding agent might cause absorbtion changes and short-term problems, but I would expect the AD effect would eventually return...

It's inexcusable that the FDA hasn't ordered Pfizer to make the old form available.

Possibly the old binding agent (can't remember what it was) aided the absorbtion of phenylzine? I wonder if one took the new Nardil with a supplement of the old binding agent (kaolin?) if it would be absorbed more effectively?

 

Re: Must I stop my beloved Nardil????? harryp

Posted by ace on May 6, 2004, at 20:48:08

In reply to Re: Must I stop my beloved Nardil????? bobbiedobbs, posted by harryp on May 4, 2004, at 4:05:50

> You didn't mention Parnate. Have you tried that? For me, it was the first and only AD that not only worked, but had no bad effects on my cognitive or creative abilities (or anything else, for that matter!).
>


Parnate cause a horrible, tearful depression in me- i hated it! I had to stop after 3 weeks and then quickly switch baclk to Nardil...

Ace

 

Re: Must I stop my beloved Nardil????? platinumbride

Posted by ace on May 6, 2004, at 20:49:31

In reply to Re: Must I stop my beloved Nardil?????, posted by platinumbride on May 5, 2004, at 13:55:56

> Have you tried neurontin? I have heard of it helping OCD and I believe that it has relatively few contraindications.
>
> Best to you,
>
> Diane

I assume these qstns are directed at me!!

Yes, I tried Neurontin for a couple of weeks at a very high dose- no effect! Maybe I could have given it longer, who knows? But it is ment to work very fast....


Ace.

 

Re: New Nardil problems harryp

Posted by ace on May 6, 2004, at 20:50:59

In reply to New Nardil problems, posted by harryp on May 6, 2004, at 19:16:16


> It's inexcusable that the FDA hasn't ordered Pfizer to make the old form available.
>
>

Absolutely. As well as disgusting. It shows a complete lack of regard for patients welfare.

Ace.

 

Stopping Nardil/Marplan? ace

Posted by bobbiedobbs on May 7, 2004, at 17:29:15

In reply to Re: Must I stop my beloved Nardil????? harryp, posted by ace on May 6, 2004, at 20:48:08

I tried Parnate after Nardil. Definitely more benign than Nardil re side effects. But did not work as well. It was just OK. Eliminated anticipatory anxiety but I was still pretty reticent to have any social interaction and pretty dysfunctional once it occured. Maybe it's not just the drugs! But Nardil definately was kickin while it lasted. Anyone tried Marplan?


> > You didn't mention Parnate. Have you tried that? For me, it was the first and only AD that not only worked, but had no bad effects on my cognitive or creative abilities (or anything else, for that matter!).
> >
>
>
> Parnate cause a horrible, tearful depression in me- i hated it! I had to stop after 3 weeks and then quickly switch baclk to Nardil...
>
> Ace
>

 

Re: Stopping Nardil/Marplan? bobbiedobbs

Posted by Ilene on May 7, 2004, at 21:43:34

In reply to Stopping Nardil/Marplan? ace, posted by bobbiedobbs on May 7, 2004, at 17:29:15

> I tried Parnate after Nardil. Definitely more benign than Nardil re side effects. But did not work as well. It was just OK. Eliminated anticipatory anxiety but I was still pretty reticent to have any social interaction and pretty dysfunctional once it occured. Maybe it's not just the drugs! But Nardil definately was kickin while it lasted. Anyone tried Marplan?
>
>
I am taking Marplan. It didn't do anything until I augmented with Cytomel (T3 thyroid hormone) about 2 weeks ago. I'm starting to feel better, but I still get anxious.

I don't have very many side effects. Some sexual problems but I'm taking several other drugs, too. I had lots of dizziness at 50 mg. so I dropped down to 40. My blood pressure was getting extremely low. The strangest SE is that I fart all the time.

 

Re: Stopping Nardil/Marplan?

Posted by tamdon on May 8, 2004, at 0:48:46

In reply to Re: Stopping Nardil/Marplan? bobbiedobbs, posted by Ilene on May 7, 2004, at 21:43:34

Is Marplan available in the United States? Bobbie Dobbs, I know exactly what you mean about Nardil. It was great for social disinhibition but the side effects, especially the exhaustion and the ear ringing, and the appetite stimulation caused me to discontinue it. It also helped with motivation. Sometimes I want to go back to it...

 

Re: Stopping Nardil/Marplan? tamdon

Posted by Ilene on May 8, 2004, at 8:10:30

In reply to Re: Stopping Nardil/Marplan?, posted by tamdon on May 8, 2004, at 0:48:46

> Is Marplan available in the United States? Bobbie Dobbs, I know exactly what you mean about Nardil. It was great for social disinhibition but the side effects, especially the exhaustion and the ear ringing, and the appetite stimulation caused me to discontinue it. It also helped with motivation. Sometimes I want to go back to it...

Marplan is distributed by Oxford Pharmaceuticals. It's not very well-known. I don't know if it is in the PDR. Here's a link:
http://www.oxfordpharm.com/marplan.htm

 

Re: Stopping Nardil/Marplan? tamdon

Posted by luther on May 8, 2004, at 10:35:20

In reply to Re: Stopping Nardil/Marplan?, posted by tamdon on May 8, 2004, at 0:48:46


> Is Marplan available in the United States? Bobbie Dobbs, I know exactly what you mean about Nardil. It was great for social disinhibition but the side effects, especially the exhaustion and the ear ringing, and the appetite stimulation caused me to discontinue it. It also helped with motivation. Sometimes I want to go back to it...

I would have to say "you don't want to go back to it now." It would be in your best interest to stay with what you are taking at this time. The new Nardil is seriously messed up and has put some in the hospital and I'm sure there has also been suicides as result. Pfizer SHOULD PAY FOR ALL THE PAIN AND SUFFERING THEY ARE AND HAVE CAUSED US!

 

Parnate ace

Posted by Questionmark on May 8, 2004, at 18:16:56

In reply to Re: Must I stop my beloved Nardil????? harryp, posted by ace on May 6, 2004, at 20:48:08

> > You didn't mention Parnate. Have you tried that? For me, it was the first and only AD that not only worked, but had no bad effects on my cognitive or creative abilities (or anything else, for that matter!).
> >
>
>
> Parnate cause a horrible, tearful depression in me- i hated it! I had to stop after 3 weeks and then quickly switch baclk to Nardil...
>
> Ace

That's really interesting, Parnate did the exact same thing for me. i was on it for about a couple months, and i was extremely over-emotional, having a number of severe, desperate crying spells, and often being in deep psychological pain. Strange that it's such an effective antidepressant (and even anxiolytic) for many people.
It seems to be good indication that, generally, people who are very emotional probably will not do as well on Parnate while people who have apathetic, anergic, and/or anhedonic depressions could probably benefit a great deal. Just my theory but i strongly believe it.


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