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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by mikel on February 5, 2002, at 8:20:36
Anyone had any luck with treating SSRI induced bruxism with Buspar? SSRI's work the best for me, but Prozac, Celexa and Effexor all cause jaw pain due to bruxism exacerbating my TMJ. As soon as I go off the SSRI the jaw pain stops, but the depression returns. Tried Serzone, did not work as well on the depression. I am currently on low dose prozac(10mg), but still get the bruxism, so I am now starting on Buspar. What dose have people tried that worked and how long did it take?
Any other meds people have tried?
Posted by petters on February 5, 2002, at 11:32:52
In reply to Buspar for SSRI induced bruxism., posted by mikel on February 5, 2002, at 8:20:36
> Anyone had any luck with treating SSRI induced bruxism with Buspar? SSRI's work the best for me, but Prozac, Celexa and Effexor all cause jaw pain due to bruxism exacerbating my TMJ. As soon as I go off the SSRI the jaw pain stops, but the depression returns. Tried Serzone, did not work as well on the depression. I am currently on low dose prozac(10mg), but still get the bruxism, so I am now starting on Buspar. What dose have people tried that worked and how long did it take?
> Any other meds people have tried?
Hi...Buspar is often very good for bruxism. Topamax also has this reputation.
Sincerely...//Petters
Posted by JohnX2 on February 5, 2002, at 23:56:51
In reply to Buspar for SSRI induced bruxism., posted by mikel on February 5, 2002, at 8:20:36
Mike,There was a published paper about Buspar being
used as an anti-dote for SSRI induced bruxism.It listed 4 cases where Zoloft was the culprit
and patients were complaining of tension headaches
and teeth grinding. Anyways the results were pretty
good, but took about 2-3 weeks.The theory behind the SSRI induced bruxism had to do
with how the medicine interacts with a certain type of serotonin
receptor. Specifically too much serotonin hiting
the sertotinin "5ht-2" type receptor would blockade dopamine
release. The dopamine that was blocked was responsable
for inhibiting the contraction of muscles in the
face/head. Buspar would fix this by reducing
serotonin firing. Other meds could reduce this
by "blocking" the "5ht-2" receptors. And then
there are meds besides Buspar that also inhibit
serotonin firing ("Gaba" medicines).Anyways, there are a number of anti-dotes
that I'll list for you that you can discuss with
your pdoc.I think a better strategy is to augment the
SSRI with a medicine that blocks the serotonin
5ht-2 receptor. For this the best candidate to add on
is probably Serzone. You can add Serzone as an
adjunct to the SSRIs to combat the bruxism.
Remeron might also help. Blocking the 5ht-2
receptor will work more quickly than using
Buspar's method. Another aproach may be to
add on a low dose of Zyprexa or an equivalent
medicine.Finally, there are medicines that work on
the Gaba system. Some are potentially habit
forming, while others are not. I know for
a fact that people have reported luck with
Baclofen. I know for a fact that Klonopin works
too.So here is a list of candidates:
5ht-1a agonist add-on to an SSRI
- Buspar I give it a 50/50 shot. Takes 2-4 weeks.5ht-2 antagonist (blockers) add-ons to an SSRI
- Serzone best candidate. Take about 1 week
- Possibly Remeron, Zyprexa and friends. Take about 1 weekGaba medicines
- Baclofen , Klonopin and friends. Same day.Regards,
John> Anyone had any luck with treating SSRI induced bruxism with Buspar? SSRI's work the best for me, but Prozac, Celexa and Effexor all cause jaw pain due to bruxism exacerbating my TMJ. As soon as I go off the SSRI the jaw pain stops, but the depression returns. Tried Serzone, did not work as well on the depression. I am currently on low dose prozac(10mg), but still get the bruxism, so I am now starting on Buspar. What dose have people tried that worked and how long did it take?
> Any other meds people have tried?
Posted by JohnX2 on February 6, 2002, at 0:05:31
In reply to Re: Buspar for SSRI induced bruxism. » mikel, posted by JohnX2 on February 5, 2002, at 23:56:51
Duh, I forgot to list the med that I am
taking for massive tension headaches which
is Topamax. I was taking Klonopin but recently
found that Topamax works just as well and is
not habit forming. Both work on the Gaba system.I've struggled with really bad tension headaches,
bruxism, weird facial pains and have found
Serzone, Zyprexa, Klonopin, and Topamax all to
alleviate my pain. Buspar did not work well for
me, but I am only 1 data point. All of the
meds I listed can be added to Prozac.Regards,
John
>
> Mike,
>
> There was a published paper about Buspar being
> used as an anti-dote for SSRI induced bruxism.
>
> It listed 4 cases where Zoloft was the culprit
> and patients were complaining of tension headaches
> and teeth grinding. Anyways the results were pretty
> good, but took about 2-3 weeks.
>
> The theory behind the SSRI induced bruxism had to do
> with how the medicine interacts with a certain type of serotonin
> receptor. Specifically too much serotonin hiting
> the sertotinin "5ht-2" type receptor would blockade dopamine
> release. The dopamine that was blocked was responsable
> for inhibiting the contraction of muscles in the
> face/head. Buspar would fix this by reducing
> serotonin firing. Other meds could reduce this
> by "blocking" the "5ht-2" receptors. And then
> there are meds besides Buspar that also inhibit
> serotonin firing ("Gaba" medicines).
>
> Anyways, there are a number of anti-dotes
> that I'll list for you that you can discuss with
> your pdoc.
>
> I think a better strategy is to augment the
> SSRI with a medicine that blocks the serotonin
> 5ht-2 receptor. For this the best candidate to add on
> is probably Serzone. You can add Serzone as an
> adjunct to the SSRIs to combat the bruxism.
> Remeron might also help. Blocking the 5ht-2
> receptor will work more quickly than using
> Buspar's method. Another aproach may be to
> add on a low dose of Zyprexa or an equivalent
> medicine.
>
> Finally, there are medicines that work on
> the Gaba system. Some are potentially habit
> forming, while others are not. I know for
> a fact that people have reported luck with
> Baclofen. I know for a fact that Klonopin works
> too.
>
> So here is a list of candidates:
>
> 5ht-1a agonist add-on to an SSRI
> - Buspar I give it a 50/50 shot. Takes 2-4 weeks.
>
> 5ht-2 antagonist (blockers) add-ons to an SSRI
> - Serzone best candidate. Take about 1 week
> - Possibly Remeron, Zyprexa and friends. Take about 1 week
>
> Gaba medicines
> - Baclofen , Klonopin and friends. Same day.
>
> Regards,
> John
>
>
>
>
>
>
>
> > Anyone had any luck with treating SSRI induced bruxism with Buspar? SSRI's work the best for me, but Prozac, Celexa and Effexor all cause jaw pain due to bruxism exacerbating my TMJ. As soon as I go off the SSRI the jaw pain stops, but the depression returns. Tried Serzone, did not work as well on the depression. I am currently on low dose prozac(10mg), but still get the bruxism, so I am now starting on Buspar. What dose have people tried that worked and how long did it take?
> > Any other meds people have tried?
Posted by Bill L on February 6, 2002, at 10:59:17
In reply to Buspar for SSRI induced bruxism., posted by mikel on February 5, 2002, at 8:20:36
If you are not successful in stopping the bruxism, you should try a mouthguard. The dentist can make one for about $150 or $200. The problem is that some people spend the money and then find that they are too uncomfortable to wear at night. You could first try a mouthguard made for bruxism at the drug store for about $15. See if you can tolerate it when you sleep. Then decide if you want to keep using that one or have one made by a dentist.
> Anyone had any luck with treating SSRI induced bruxism with Buspar? SSRI's work the best for me, but Prozac, Celexa and Effexor all cause jaw pain due to bruxism exacerbating my TMJ. As soon as I go off the SSRI the jaw pain stops, but the depression returns. Tried Serzone, did not work as well on the depression. I am currently on low dose prozac(10mg), but still get the bruxism, so I am now starting on Buspar. What dose have people tried that worked and how long did it take?
> Any other meds people have tried?
Posted by katieb on February 7, 2002, at 10:51:03
In reply to Re: Buspar for SSRI induced bruxism., posted by Bill L on February 6, 2002, at 10:59:17
i had a lot of success in reducing the clenching on 15mg buspar (7.5 two times a day). the whole problem went away w/i 1-2 weeks.
good luck!
Posted by LynnPerley on April 26, 2003, at 11:11:21
In reply to Re: Buspar for SSRI induced bruxism., posted by katieb on February 7, 2002, at 10:51:03
I am bringing up an old thread here. I've been taking EffexorXR successfully and the bruxism side effect was less noticeable than on Prozac. I've suffered an increase in anxiety and a relapse of depression following my husband's military mobilization (he's a reservist and was deployed to the middle east about 90 days ago). I finally went to a psydoc and she has increased my EffexorXR to 300mg (I was at 225mg for over 6 months). She also added Buspar, telling me to take 5mg or 10mg at night, because as my mental state declined the bruxism has become more apparent and is giving me tension headaches.
I'd like to hear any anecdotes from those who have added buspar as an antidote for bruxism. What dosage, and how long did it take to show any effect?
I'm having increased spacyness but I don't know if it is the 300mg of EffexorXR or the buspar at this point. I've only been taking 5mg of buspar at night when I take my effexorxr but if my schedule allows me to sleep in tomorrow I will probably increase it to 10mg.
Posted by chris29 on March 21, 2007, at 15:14:58
In reply to Buspar for SSRI induced bruxism., posted by LynnPerley on April 26, 2003, at 11:11:21
I take luvox, 50mg with buspar 5-10mg, it works well to reduce muscle tension caused from the SSRI. I keep the doses low, the higher the dose, the more tension I get. Also Elavil 25mg at night on occasion, or valium 5mg helps with headaches and TMJ pain, regardless of weither its induced by meds or if you have it naturally.
I have TMJ naturally so on top of it I have to be careful. I have not tried Topomax, Klonapin does work also but it makes me very depressed as a side effect, so it negates the whole antidepressant idea. Its the most depressing of the benzos. Also prozac and buspar interact with one another, and the prozac doesnt work as well, thats why I switched to luvox. Anything that helps TMJ is basically going to reduce your serotonin, so I reccomend a small dose of buspar 5-10 mg a day one hour after you take you SSRI. Dont take at same time.
This is the end of the thread.
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