Posted by JohnX2 on February 6, 2002, at 0:05:31
In reply to Re: Buspar for SSRI induced bruxism. » mikel, posted by JohnX2 on February 5, 2002, at 23:56:51
Duh, I forgot to list the med that I am
taking for massive tension headaches which
is Topamax. I was taking Klonopin but recently
found that Topamax works just as well and is
not habit forming. Both work on the Gaba system.I've struggled with really bad tension headaches,
bruxism, weird facial pains and have found
Serzone, Zyprexa, Klonopin, and Topamax all to
alleviate my pain. Buspar did not work well for
me, but I am only 1 data point. All of the
meds I listed can be added to Prozac.Regards,
John
>
> Mike,
>
> There was a published paper about Buspar being
> used as an anti-dote for SSRI induced bruxism.
>
> It listed 4 cases where Zoloft was the culprit
> and patients were complaining of tension headaches
> and teeth grinding. Anyways the results were pretty
> good, but took about 2-3 weeks.
>
> The theory behind the SSRI induced bruxism had to do
> with how the medicine interacts with a certain type of serotonin
> receptor. Specifically too much serotonin hiting
> the sertotinin "5ht-2" type receptor would blockade dopamine
> release. The dopamine that was blocked was responsable
> for inhibiting the contraction of muscles in the
> face/head. Buspar would fix this by reducing
> serotonin firing. Other meds could reduce this
> by "blocking" the "5ht-2" receptors. And then
> there are meds besides Buspar that also inhibit
> serotonin firing ("Gaba" medicines).
>
> Anyways, there are a number of anti-dotes
> that I'll list for you that you can discuss with
> your pdoc.
>
> I think a better strategy is to augment the
> SSRI with a medicine that blocks the serotonin
> 5ht-2 receptor. For this the best candidate to add on
> is probably Serzone. You can add Serzone as an
> adjunct to the SSRIs to combat the bruxism.
> Remeron might also help. Blocking the 5ht-2
> receptor will work more quickly than using
> Buspar's method. Another aproach may be to
> add on a low dose of Zyprexa or an equivalent
> medicine.
>
> Finally, there are medicines that work on
> the Gaba system. Some are potentially habit
> forming, while others are not. I know for
> a fact that people have reported luck with
> Baclofen. I know for a fact that Klonopin works
> too.
>
> So here is a list of candidates:
>
> 5ht-1a agonist add-on to an SSRI
> - Buspar I give it a 50/50 shot. Takes 2-4 weeks.
>
> 5ht-2 antagonist (blockers) add-ons to an SSRI
> - Serzone best candidate. Take about 1 week
> - Possibly Remeron, Zyprexa and friends. Take about 1 week
>
> Gaba medicines
> - Baclofen , Klonopin and friends. Same day.
>
> Regards,
> John
>
>
>
>
>
>
>
> > Anyone had any luck with treating SSRI induced bruxism with Buspar? SSRI's work the best for me, but Prozac, Celexa and Effexor all cause jaw pain due to bruxism exacerbating my TMJ. As soon as I go off the SSRI the jaw pain stops, but the depression returns. Tried Serzone, did not work as well on the depression. I am currently on low dose prozac(10mg), but still get the bruxism, so I am now starting on Buspar. What dose have people tried that worked and how long did it take?
> > Any other meds people have tried?
poster:JohnX2
thread:92947
URL: http://www.dr-bob.org/babble/20020131/msgs/93038.html