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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Anon on January 23, 2000, at 20:00:26
Just got word from inside Pharmacia and Upjohn - the FDA
will deliver their version of what the package insert should look like
by late February. If P&U sees what it likes, it will be available by
May. If not, it likely will never be available in the US. Too expensive
to do more studies to satisfy the FDA. The first package insert for
Reboxetine from the FDA contained some wording that would have crippled
sales dramatically. We'll see.
Posted by steve on January 23, 2000, at 20:10:59
In reply to Reboxetine's future in the USA, posted by Anon on January 23, 2000, at 20:00:26
What was that wording?
> Just got word from inside Pharmacia and Upjohn - the FDA
> will deliver their version of what the package insert should look like
> by late February. If P&U sees what it likes, it will be available by
> May. If not, it likely will never be available in the US. Too expensive
> to do more studies to satisfy the FDA. The first package insert for
> Reboxetine from the FDA contained some wording that would have crippled
> sales dramatically. We'll see.
Posted by halifax on January 23, 2000, at 22:36:06
In reply to Re: Reboxetine's future in the USA, posted by steve on January 23, 2000, at 20:10:59
This board has several people either taking reboxetine, or who are very interested in taking the drug. Is the reason for all the buzz because it is the newest antidepressant, or does reboxetine have desirable qualities other antidepressants don't? what is reboxetine classified as.....SSRI, SNRI, something else?
this board has such wonderful information. thank-you.
Posted by dj -- Vancouver on January 23, 2000, at 22:49:30
In reply to reboxetine questions, posted by halifax on January 23, 2000, at 22:36:06
BTW, when addressing Halifax's questions if anyone has any info. on the availability of reboxetine in Canada please let us Canucks know the status. Thanks!
> This board has several people either taking reboxetine, or who are very interested in taking the drug. Is the reason for all the buzz because it is the newest antidepressant, or does reboxetine have desirable qualities other antidepressants don't? what is reboxetine classified as.....SSRI, SNRI, something else?
>
> this board has such wonderful information. thank-you.
Posted by Bruce on January 24, 2000, at 11:08:48
In reply to reboxetine questions, posted by halifax on January 23, 2000, at 22:36:06
> This board has several people either taking reboxetine, or who are very interested in taking the drug. Is the reason for all the buzz because it is the newest antidepressant, or does reboxetine have desirable qualities other antidepressants don't? what is reboxetine classified as.....SSRI, SNRI, something else?
>
> this board has such wonderful information. thank-you.
Reboxetine is a NARI (Noradrenergic Reuptake Inhibitor). It prevents the reuptake of norepinephrine, and is very selective indoing so (it has no effect on serotonin, maybe a small positive effect on dopamine).The norepinephrine system is related to energy, reward, drive , and motivation. My own experiences with Reboxetine seem to back this up. Side effects are the anti-cholinergic ones (constipation, dysuria, retrograde ejaculation) and insomnia. As always, YMMV.
Bruce
Posted by Luke on January 24, 2000, at 23:42:27
In reply to Re: reboxetine questions, posted by Bruce on January 24, 2000, at 11:08:48
> Reboxetine is a NARI (Noradrenergic Reuptake Inhibitor). It prevents the reuptake of norepinephrine, and is very selective indoing so (it has no effect on serotonin, maybe a small positive effect on dopamine).
>
> The norepinephrine system is related to energy, reward, drive , and motivation. My own experiences with Reboxetine seem to back this up. Side effects are the anti-cholinergic ones (constipation, dysuria, retrograde ejaculation) and insomnia. As always, YMMV.
>
> BruceI have been on rebox for more than three months, and for me, almost everything Bruce says holds true - the energy, drive, etc. Fortunatley for me, I am luckier than Bruce and some others when it comes to side effects. I never experienced any insomnia or constipation at all, and the dysuria and sex problems have diminished to very tolerable levels. At first, however, they were awful.
Good luck,
Luke
Posted by torchgrl on January 25, 2000, at 0:51:06
In reply to Re: reboxetine questions, posted by Luke on January 24, 2000, at 23:42:27
Luke, I'm curious how long it took before you noticed the effects on drive, motivation etc? I was on rebox. for about 10 weeks, and barely noticed any effect at all on the maximum doseage... It just wasn't worth the rigamarole I'd have had to deal with to stay on it any longer, but I'm wondering if full effects just take a long time to hit. Everyone else seems to have noticed beneficial effects but me! :(
Posted by VinJoe on January 26, 2000, at 16:27:24
In reply to Re: reboxetine questions, posted by torchgrl on January 25, 2000, at 0:51:06
> Luke, I'm curious how long it took before you noticed the effects on drive, motivation etc? I was on rebox. for about 10 weeks, and barely noticed any effect at all on the maximum doseage... It just wasn't worth the rigamarole I'd have had to deal with to stay on it any longer, but I'm wondering if full effects just take a long time to hit. Everyone else seems to have noticed beneficial effects but me! :(
I've been waiting for the intro of Reboxetine in the US for quite a while because of the number of positive responses that have been cited and needless to say, I'm very disappointed at the May (or possibly never) date suggested on this Bul Board. Has anyone had any success going outside US to acquire? If so, any guidance on such a strategy would be greatly appreciated.
This is the end of the thread.
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