Psycho-Babble Medication Thread 4268

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Dosage changes--how soon do they kick in?

Posted by Victoria on April 1, 1999, at 11:59:53

What experience have you had with changing dosages of SSRIs? It has taken the usual 4-6 weeks for one to take effect at the beginning. But how quickly can dose changes take effect after that? I recently increased trazadone from 50mg to 100 mg (on doc's advice). Side effects kicked in right away (heavy night sweats, which I also had with Zoloft), so after about a week, I cut back again. But I now think that there was a "time-delay" effect on my mood--a significant improvement that began about 5 days after I increased the dose and lasted about 5 days after I cut back (then I crashed). Since my moods can be changeable anyway, it's hard for me to be sure if the improvement was the meds. So, I was wondering what other people had experienced when changing dosages? thanks!

 

Re: Dosage changes--how soon do they kick in?

Posted by saintjames on April 1, 1999, at 14:44:32

In reply to Dosage changes--how soon do they kick in?, posted by Victoria on April 1, 1999, at 11:59:53

> What experience have you had with changing dosages of SSRIs? It has taken the usual 4-6 weeks for one to take effect at the beginning. But how quickly can dose changes take effect after that? I recently increased trazadone from 50mg to 100 mg (on doc's advice). Side effects kicked in right away (heavy night sweats, which I also had with Zoloft), so after about a week, I cut back again. But I now think that there was a "time-delay" effect on my mood--a significant improvement that began about 5 days after I increased the dose and lasted about 5 days after I cut back (then I crashed). Since my moods can be changeable anyway, it's hard for me to be sure if the improvement was the meds. So, I was wondering what other people had experienced when changing dosages? thanks!

James here.....

For me when I changed from TCA to TCA the new med kicked in w/i a week. With the newer AD's (all being different chemicals) it took several weeks to get the full effect. As the old med cleared out of my system for ~ 2 weeks I did benifit from
still being on the old med.

james

 

Re: Dosage changes--how soon do they kick in?

Posted by Matt on April 1, 1999, at 22:30:38

In reply to Re: Dosage changes--how soon do they kick in?, posted by saintjames on April 1, 1999, at 14:44:32

I've noticed immediate changes a few times when augmenting one drug with another. I usually don't notice changes in antidepressant effect for a while after changing doses, though I usually do notice effects on my anxiety very soon after changing doses.

Matt


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