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Dr. Bob is Robert Hsiung, MD,
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Posted by iforgotmypassword on February 26, 2010, at 8:21:17
to a higher degree than levomethylphenidate.
does anyone know any specifics, the degree of affinity, and especially the intrinsic efficacy?
thanks.
Posted by linkadge on February 26, 2010, at 8:21:17
In reply to dexmethylphenidate has 5-ht1a affinity, posted by iforgotmypassword on February 19, 2010, at 19:32:53
I'm not exactly sure. I read about this a while back. D-meth also has higher affinity for the norepinephrine reuptake pump.
It kind of makes it like norquetiapine (ie an NRI and 5-ht1a agonist).
Both 5-ht1a agonism and NRI will increase prefrontal catecholamine activity. But, I have no idea how strong it is at 5-ht1a.
Linkadge
Posted by tom2228 on May 10, 2010, at 16:46:44
In reply to Re: dexmethylphenidate has 5-ht1a affinity, posted by linkadge on February 26, 2010, at 8:21:17
Not sure of the affinities of d-mph, it's kind of hard to find. But I was on Focalin for about 8 months, from last August to this March, and I can tell you personally d-MPH is deFinitely a 5-HT1a agonist, that's for sure.
This is the end of the thread.
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