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Dr. Bob is Robert Hsiung, MD,
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Posted by Mtom on May 3, 2018, at 10:15:16
Does Turmeric interact dangerously with anti-depressants? Reading conflicting opinions. Some say no, does not affect neurotransmitters the same way. Others say it may increase Serotonin activity or act as an MAOI, and combining with antidepressants could potentially cause Serotonin Syndrome. Experienced SS once with Zoloft, it's terrifying.
Have avoided antidepressants ever since. Have been taking Turmeric for some time but no effect (maybe not taking enough?). Seeing Doctor today to again revisit Antidepressant possibilities, but concerned that I have been taking Turmeric.
Been trying to research, it's contradictory or hypothetical. Can anyone provide more research on this? Thanks.....
Posted by linkadge on July 10, 2018, at 20:13:37
In reply to Turmeric/AD interactions? Reading yes/no/maybe?, posted by Mtom on May 3, 2018, at 10:15:16
I think it is fairly safe. I take low dose venlafaxine, and turmeric with little problem.
It is supposedly an MAOI (in higher doses), although I read a report recently suggesting that its antidepressant effect was due to other mechanisms (i.e. no MAO activity detected in depression effective doses).
I think you would need a fairly high dose of turmeric (10's of grams) before MAOI activity is an issue. Also note, there are many 'natural' MAOIs which don't seem to interact with antidepressants for some unbeknownst reason.
For example, smokers supposedly have 30-50% lower MAO because of tobacco, yet many smokers take SSRIs with no issue.
Coffee also contains MAOIs.
I wouldn't worry about it unless you are taking really high doses of turmeric.
Linkadge
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