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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by chrismeurer on October 2, 2018, at 17:34:35
Hello,
It has been almost one year since I started taking parnate. At first, I had huge blood pressure drops, but did not feel tired or had much difficult getting to sleep. After a few months, though, I started to feel extremelly exhausted. Also, I felt a mild discomfort in my legs that got progressively worse until I began sleep with my legs elevated. I was constantly feeling that there was not enough oxygen, this shortness of breath.
I wondered what was happening. After some research, I came across the information that parnate could actually decrease norepinephrine levels in the brain. Talking to my doctor, she agreed to add a low dose (20 mg) of nortriptyline to the 60 mg parnate I take daily. After one week, I feel much less tired. It's an interesting result, I think. I will give it a few more weeks until I can be sure the effect is permanent.
Just thought it would be nice to share this with you. I didn't come here as often as I did before. I posted a few times. Thank you for the support and knowledge you provide!
Christian Meurer
Posted by rjlockhart37 on October 4, 2018, at 23:23:54
In reply to Follow-up parnate treatment, posted by chrismeurer on October 2, 2018, at 17:34:35
glad that things are better, parnate not sure if it's accurate but it's one the most strongest anti-depressant there is, that with nardil. But the tired feeling, i've read on babble over the years, it gives energy and improvement in mood, then you become tired and fatigued later in the day. I don't know why parnate doest t his, but it's a hard-core anti-depressant, very effective but lots of side effects
this is on wikipedia
"In one study, nortriptyline had the highest affinity for the dopamine transporter among the TCAs" but that was only one study, but maybe that could be the case. It's a good serotonin TCA, but yes, keep updated. Glad it's working so far, wait for others posters to post their thoughts
This is the end of the thread.
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