Psycho-Babble Medication Thread 1043276

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Which drug is doing which sideeffect?

Posted by gpznos on May 6, 2013, at 12:36:14

Hi all
I am on a combo of 135 mg Nortriptyline, 600 mg Lithium and most resently 30 mg Marplan (MAOi) was added.
When I was only on Nort I didnt notice many SEs - most prominent was dry mouth.
Now I have all sorts of SEs and I cant tell which SE is coming from which drug. Maybe some of you can help? Here they are:
- VERY dry mouth
- Heavy sweating at night
- Delayed ejaculation and reduced sexual drive

- Wanting to eat a lot more => weight increase
- Constipation (fixed by lots of magnesia)
- Sleep interuptions

The most annoying SEs are the first 3 mentioned.

I am considering to increase the Marplan and maybe be able to reduce the Nort or Lithium. But will increasing the Marplan, increase the SEs?

Which drug is the most likely to do which sideeffect?

 

Re: Which drug is doing which sideeffect?

Posted by Tyrannosaur on May 6, 2013, at 16:01:40

In reply to Which drug is doing which sideeffect?, posted by gpznos on May 6, 2013, at 12:36:14

Dry mouth = Impossible to say, all three meds are known to cause this.

Heavy sweating = Once again all three medications can cause this, but I'd say it is most likely Lithium.

Delayed ejaculation and reduced sexual drive = This is caused by Marplan 99%

Wanting to eat a lot more => weight increase = Most likely caused by Marplan

Constipation = Most likely caused by Marplan

Sleep interruptions = All three medications can cause this.


It would be easier to answer these questions if you mentioned when these side effects appeared, and when you started each medication, as well as what dose you were using of each medication when each side effect appeared. This might be hard to remember, but it would make everything much easier.

 

Re: Which drug is doing which sideeffect?

Posted by gpznos on May 8, 2013, at 5:39:18

In reply to Re: Which drug is doing which sideeffect?, posted by Tyrannosaur on May 6, 2013, at 16:01:40

> Dry mouth = Impossible to say, all three meds are known to cause this.
>
> Heavy sweating = Once again all three medications can cause this, but I'd say it is most likely Lithium.
>
> Delayed ejaculation and reduced sexual drive = This is caused by Marplan 99%
>
> Wanting to eat a lot more => weight increase = Most likely caused by Marplan
>
> Constipation = Most likely caused by Marplan
>
> Sleep interruptions = All three medications can cause this.
>
>
> It would be easier to answer these questions if you mentioned when these side effects appeared, and when you started each medication, as well as what dose you were using of each medication when each side effect appeared. This might be hard to remember, but it would make everything much easier.
>
>
>

Hi T, thanks for your answer. Yes I know. Some of the sexual SE came along with the Lithium for sure but Marplan has made it worse. The problem is I really want to increase the Marplan but I fear the SE will be even stronger. So I am thinking about lowering either the Nort or the Lithium to hopefully lessen the SEs...

 

Re: Which drug is doing which sideeffect?

Posted by Tyrannosaur on May 8, 2013, at 17:34:24

In reply to Re: Which drug is doing which sideeffect?, posted by gpznos on May 8, 2013, at 5:39:18

I didn't know Lithium caused sexual side effects, everything I've read said it did nothing, or improved the stuff that happens in the bedroom.

Marplan however is very similar to Nardil, and it's known to cause constipation, postural hypotension, erectile dysfunction, insomnia, sedation and so on. These side effects do normally increase with higher dose.
The positive is that a lot of the side effects tend to lessen or disappear after being a couple of months on the medication.

Trying to lower or remove Nortriptyline or Lithium sounds like a good idea, if it doesn't give satisfying results you could just reinstate the original dose.


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