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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by zonked on June 28, 2011, at 15:03:56
Doxlamine 12.5mg (1 tablet cut in half) - last night I had the most refreshing sleep I can remember in a long time...
I'm telling you, the benefits continue as I've been on Nardil longer. I also managed to avoid the "nap attack" in the afternoon (although caffeine was involved!)
-z
Posted by Phillipa on June 28, 2011, at 17:50:15
In reply to Nardil insomnia: fixed (doxylamine 12.5mg), posted by zonked on June 28, 2011, at 15:03:56
That's great zonked don't know that med will google. Phillipa
Posted by jono_in_adelaide on June 28, 2011, at 22:30:02
In reply to Re: Nardil insomnia: fixed (doxylamine 12.5mg) » zonked, posted by Phillipa on June 28, 2011, at 17:50:15
Doxylamine susscinate is an sedating antihistamine from the same family as diphenhydramine (Benadryl, Sominex etc)
It is the active constituent of Unisom, and is one of many ingredients in Vicks Nyquil
Posted by emmanuel98 on June 28, 2011, at 23:43:47
In reply to Re: Nardil insomnia: fixed (doxylamine 12.5mg), posted by jono_in_adelaide on June 28, 2011, at 22:30:02
Funny. I was told by my pharmacist that this class of drugs are absolutely contraindicated with Parnate. I would assume Nardil also.
Posted by jono_in_adelaide on June 29, 2011, at 1:10:38
In reply to Re: Nardil insomnia: fixed (doxylamine 12.5mg), posted by emmanuel98 on June 28, 2011, at 23:43:47
Sadly, a lot of doctors and pharmacists take the soft option of saying that everything is contraindicated with MAOI's without specialist advice, including ibuprofen, Tums and Milk of Magensia.
Ask the reason for the contraindication, the nature of the reaction, and see what answer you get.
Posted by SLS on June 29, 2011, at 4:51:48
In reply to Re: Nardil insomnia: fixed (doxylamine 12.5mg), posted by jono_in_adelaide on June 29, 2011, at 1:10:38
> Sadly, a lot of doctors and pharmacists take the soft option of saying that everything is contraindicated with MAOI's without specialist advice, including ibuprofen, Tums and Milk of Magensia.
>
> Ask the reason for the contraindication, the nature of the reaction, and see what answer you get.
>
>My first round with Parnate + Benadryl yielded inadequate sleep, but did not produce serotonin syndrome. I am not sure what the contraindication is about. Perhaps it is a theoretical concern of the serotonin reuptake inhibition that some antihistamines exhibit.
- Scott
Posted by viper1431 on June 29, 2011, at 7:47:22
In reply to Re: Nardil insomnia: fixed (doxylamine 12.5mg), posted by emmanuel98 on June 28, 2011, at 23:43:47
The computers the docs here in AUS bring up a warning saying anti-histamines are contradicted with maoi's.. saw it the other day when my doc was prescribing me something, however when he checked the reason it just said it may increase the effects of the anti-histamine. We both just thought "bonus"
> Funny. I was told by my pharmacist that this class of drugs are absolutely contraindicated with Parnate. I would assume Nardil also.
Posted by Lamdage on June 29, 2011, at 18:15:27
In reply to Nardil insomnia: fixed (doxylamine 12.5mg), posted by zonked on June 28, 2011, at 15:03:56
> Doxlamine 12.5mg (1 tablet cut in half) - last night I had the most refreshing sleep I can remember in a long time...
>
> I'm telling you, the benefits continue as I've been on Nardil longer. I also managed to avoid the "nap attack" in the afternoon (although caffeine was involved!)
>
> -zInteresting. I didnt find doxylamine to do much.. then again i have had my diphenhydramine tolerance built up alot. Maybe building tolerance to one means tolerance for the other as well.
I am happy to have a whole bunch of sedatives/hypnotics that work exceptionally well including baclofen, neurontin, trazodone(works well, without hangover), a weak antipsychotic you probably havent heard of, seroquel, diphenhydramine.. I am equipped for a two year hibernation lol.Do sedatives provide protection of mania? I mean a couple nights of 10 hour sleep will prevent mania, right?!?
Its a good feeling that i am perfectly equipped for nardils insomnia. All the weapons i have, it has no chance whatsoever.
Btw glad to hear nardil is continuing to work for ya! Myself, i feel some effects already but wouldnt say it has really kicked in yet.
Take careLd
Posted by zonked on June 29, 2011, at 20:07:44
In reply to Re: Nardil insomnia: fixed (doxylamine 12.5mg), posted by Lamdage on June 29, 2011, at 18:15:27
L- It wouldn't surprise me if cross tolerance between antihistamines could be an issue. As for sedatives providing protection against mania, it depends on what you mean by "sedative" =) Seroquel yes (although you couldn't pay me to take that stuff) benzos yep, with Klonopin in particular being clinically proven as an adjunct. How long has it been now, on Nardil? Looking forward to when you can join our little PB Nardil responders club =) -z
Posted by jono_in_adelaide on June 30, 2011, at 0:14:56
In reply to Re: Nardil insomnia and misc » Lamdage, posted by zonked on June 29, 2011, at 20:07:44
Yes, there will be cross tolorance between antihistaminic sedatives, including antipsychotics and antidepressants (regular use of doxepin or amitriptyline would negate the sedating effect of benadryl)
Posted by Lamdage on June 30, 2011, at 1:03:32
In reply to Re: Nardil insomnia and misc, posted by jono_in_adelaide on June 30, 2011, at 0:14:56
> Yes, there will be cross tolorance between antihistaminic sedatives, including antipsychotics and antidepressants (regular use of doxepin or amitriptyline would negate the sedating effect of benadryl)
There i go. Luckily this is no issue anymore. Man have i been sleeping in the last 24 hours. I took 400mg gabapentin and 25 mg baclofen at 11 am.. Dude i was utterly knocked out.. total of like 14 hours sleep. Including my complete trainride to switzerland(im picking up a pfizer batch phenelzine here). Looking at doing some sightseeing, too.
Zonked its been a little more a week. I did something like a Mao destruction weekend with 75mg phenelzine now slowly going back to my normal dosage 45mg. Its a bit agressive but what the heck.. i tolerate it well and i have decent mania protection in place.
PB meaning.. pacific beach? or am i completely dumb?Ld
Posted by Lamdage on June 30, 2011, at 3:59:11
In reply to Re: Nardil insomnia and misc, posted by Lamdage on June 30, 2011, at 1:03:32
Whoops.. right pacific beach. Thats what would be called wishful thinking.
Thanks i cant wait to join the responder club!
This is the end of the thread.
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