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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by alexcanada on November 6, 2010, at 19:06:26
From what I've read on here it seems Parnate is generally a med that requires a lot of dose changing. Is this a general rule? If so how often do you have to. Is it similar for all MAOI's?
Also how do you know that you need to? Also how do you know if you are too low or too high in particular?
I been feeling worse and worse lately. I have atypical depression with low drive, motivation, concentration, tiredness, very anti-social, etc. Maybe my meds dont play well with Parnate or i seriously need an increase or reduction. But my dose is low enough as it is. I used to be on doses such as 20mg, 25mg, and 30mg a day this year. The 20mg and 25 have usually been the better ones. Yet 2 years ago I felt my best days on parnate when I was as low as 10mg and 15mg parnate along with some ritalin. I still take ritalin usually. I also take gabapentin but it seems to last only for a limited time such as month or so and then becomes more mild.
My body has been feeling extremely warm lately. Is this related to Parnate? It's hard to sleep.
Also if someone could tell me what could go well with Parnate I would appreciate any suggestions. benzos used to work somewhat well for me but maybe i developed too much tolerance to them as taking a valium after many days of not doing so doesn't seem to cause any upswing.
Posted by Maxime on November 6, 2010, at 19:54:14
In reply to Parnate constant dose changes? Plus warm body, posted by alexcanada on November 6, 2010, at 19:06:26
> My body has been feeling extremely warm lately. Is this related to Parnate? It's hard to sleep.
>
> Also if someone could tell me what could go well with Parnate I would appreciate any suggestions. benzos used to work somewhat well for me but maybe i developed too much tolerance to them as taking a valium after many days of not doing so doesn't seem to cause any upswing.Yes, Parnate causes the body to overheat. You have to be careful in the summer months. I don't know why it does it, I just know that it does from experience. Nardil does the same thing.
So you want to mix something with Parnate, but what effect are you looking for? A you looking for a stronger anti-depressant effect? Something for anxiety?
Posted by alexcanada on November 6, 2010, at 19:59:09
In reply to Re: Parnate constant dose changes? Plus warm body » alexcanada, posted by Maxime on November 6, 2010, at 19:54:14
> > My body has been feeling extremely warm lately. Is this related to Parnate? It's hard to sleep.
> >
> > Also if someone could tell me what could go well with Parnate I would appreciate any suggestions. benzos used to work somewhat well for me but maybe i developed too much tolerance to them as taking a valium after many days of not doing so doesn't seem to cause any upswing.
>
> Yes, Parnate causes the body to overheat. You have to be careful in the summer months. I don't know why it does it, I just know that it does from experience. Nardil does the same thing.
>
> So you want to mix something with Parnate, but what effect are you looking for? A you looking for a stronger anti-depressant effect? Something for anxiety?something to help this poor depression. my concentration is especially awful and i feel very drained physically. low energy. poor sleep. hard to think. some social anxiety relief could help but i need to feel better to have any desire for communication to begin with. right now i feel like i am burden around others. i feel disconnected mentally from everyone else. i cannot relate to all these so called normal people. when i feel better it's easier to be able to. i lack enjoyment in anything around me.
Posted by Maxime on November 6, 2010, at 20:17:19
In reply to Re: My Symptoms... » Maxime, posted by alexcanada on November 6, 2010, at 19:59:09
>
> something to help this poor depression. my concentration is especially awful and i feel very drained physically. low energy. poor sleep. hard to think. some social anxiety relief could help but i need to feel better to have any desire for communication to begin with. right now i feel like i am burden around others. i feel disconnected mentally from everyone else. i cannot relate to all these so called normal people. when i feel better it's easier to be able to. i lack enjoyment in anything around me.
>
>
>I really feel for you. Do you think it's possible that Parnate isn't right for you? It doesn't seem to be helping *at all* if you have those symptoms. Are there any ADs that have worked in the past? Does your psychiatrist have any suggestions?
Posted by alexcanada on November 9, 2010, at 3:04:21
In reply to Re: My Symptoms... » alexcanada, posted by Maxime on November 6, 2010, at 20:17:19
> >
> > something to help this poor depression. my concentration is especially awful and i feel very drained physically. low energy. poor sleep. hard to think. some social anxiety relief could help but i need to feel better to have any desire for communication to begin with. right now i feel like i am burden around others. i feel disconnected mentally from everyone else. i cannot relate to all these so called normal people. when i feel better it's easier to be able to. i lack enjoyment in anything around me.
> >
> >
> >
>
> I really feel for you. Do you think it's possible that Parnate isn't right for you? It doesn't seem to be helping *at all* if you have those symptoms. Are there any ADs that have worked in the past? Does your psychiatrist have any suggestions?parnate is one of the few which has helped. and i raised my dose a few days ago with a very significant benifit towards my mood, drive, motivation, enjoyment and productivity! i'm on 25mg now and 22.5mg the day before and 15mg the day prior. something like that. 10mg was the lowest i went in a while. i think dropping the valium is one of the things which ended up helping as perhaps it wasn't playing well with parn. since it's strange how back up to 25mg i am feeling better (even though it's likely the initial amphetamine type effect) relatively speaking.
BUT... my sleep right now is horrendous. My insomnia is massive and zero sleep two nights ago and this night i had slept a grand total of 1.5 or 2 hours. i was able to fall asleep after being in bed for a long while and despite being brutally exhausted i woke up after that short dream filled sleep and not able to fall asleep again. it's so frustrating to know i would be feeling decent if it wasn't for this insomnia.
how on earth do i deal with it? doctor wont give me anything unless i come with some ideas. he is out of options. anti-psychotics ruin any positive effect parnate has had for me in the past and zipicone (spelling) doesn't work, over the counter stuff has very limited effect from what i tried such as benadryl allergy, gravol, and typical sleep aids, valium i'm not sure if it does anything, drinking is too expensive and even that i am not sure if it helps.
to answer your question paxil worked for me in a limited fashion in the past but may have began to poop out when i was on it a year ago. remeron gave some relief as well. stablon worked to a degree. risperidone was one of the first to make me feel like i wasn't in constant pain several years ago. many others have failed me and made me worse such as celexa, effexor, cymbalta etc.
Posted by Maxime on November 9, 2010, at 17:02:10
In reply to mixed success lately! But Insomnia is Extreme, posted by alexcanada on November 9, 2010, at 3:04:21
I am glad the increase in Parnate helped you. I don't know what to suggest for sleeping. Have you ever taken a benzo short term? The insomnia is from the Parnate (I am pretty sure) and will go away. I had trouble sleeping for about a month when I started Parnate back in October. I took Thorazine/Largictal to help me. It's an old anti-psychotic. But eventually I didn't need it anymore.
Also, maybe you could try something alternative to help you with sleep.
Keep pushing.
Posted by emmanuel98 on November 9, 2010, at 21:01:22
In reply to mixed success lately! But Insomnia is Extreme, posted by alexcanada on November 9, 2010, at 3:04:21
I also have terrible insomnia from parnate. I take 100mg of trazodone and 2 mg of ativan every night before bed. I know trazadone is contra-indicated with parnate, but my p-doc and I decided to try in anyway and watch carefully for signs of serotonin syndrome. So far it's been no problem. I only take 30mg of parnate and that works for me. Once, a few months ago, I felt my depression was coming back and I went up to 40 mg, but that didn't seem to make a difference, so I went back to 30. After a few weeks, I was fine again. I think the depression last time was mostly situational and not biological.
Posted by B2Chica on November 15, 2010, at 11:38:53
In reply to mixed success lately! But Insomnia is Extreme, posted by alexcanada on November 9, 2010, at 3:04:21
idont know ANYTHING about parnate so please check with pdoc. but i finally found something that's helping with my HORRIBLE insomnia (that wasnt an AP)
i take gabapentin during the day for anxiety and at first it makes you pretty drowsy, so i take it at night too. also i take klonipin 2mg (or 1/2 extra one if needed). that really seemed to help.pdoc just started me on abilify, so thats' REALLy helping the situation too.
but checkout the neurontin/gabapentin and klonipin combo?
worth a shot.otherwise zyprexa ALWAYS worked for me...for Everythhing.
alas, i'm still trying to loose baby fat, so i refuse it.Best wishes.
b2c.
Posted by alexcanada on November 16, 2010, at 0:03:28
In reply to Re: mixed success lately! But Insomnia is Extreme, posted by B2Chica on November 15, 2010, at 11:38:53
i have gabapentin. i take it only once in a while now because it's becoming hard to afford. i don't know if i can manage to take it for sleep. it's best for me to take it during the day because it helps lift my mood a bit even though it initially makes me feel lousy for 45 minutes... then followed by 4 hours of improvement. it's too difficult to be social or productive without it. but the more i take it the quicker it develops tolerance.
how often do you take it daily for your mood? my insomnia is starting to wittle down but also the parnate benifitial effect has as well ;(
> idont know ANYTHING about parnate so please check with pdoc. but i finally found something that's helping with my HORRIBLE insomnia (that wasnt an AP)
> i take gabapentin during the day for anxiety and at first it makes you pretty drowsy, so i take it at night too. also i take klonipin 2mg (or 1/2 extra one if needed). that really seemed to help.
>
> pdoc just started me on abilify, so thats' REALLy helping the situation too.
> but checkout the neurontin/gabapentin and klonipin combo?
> worth a shot.
>
> otherwise zyprexa ALWAYS worked for me...for Everythhing.
> alas, i'm still trying to loose baby fat, so i refuse it.
>
> Best wishes.
> b2c.
This is the end of the thread.
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