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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Conundrum on October 5, 2010, at 11:15:29
I've been having trouble with new drugs that just don't work or stop working.
The ones that stopped working include:
pristiq, remeron, abilify, and lamotrigine.Ritalin can pull me out of a bad mood, but doesn't help with anhedonia, or motivation, surprisingly
The ones that did nothing were lexapro, budeprion SR.
The only thing that partially works consistently is low dose prozac, which helps with motivation and somewhat with enjoyment.
Maybe I should try to augment that.
Maybe I should just go for an MAOI.
I'm also considering tianeptine, which is an indirect 5-HT antagonist, but it sounds like it is weak and mainly for anxiety.
My grandmother tried a bunch of TCA and none worked. She tried Parnate and it worked. Stopped for some reason and went on Nardil and that worked as well.
Posted by Phillipa on October 5, 2010, at 12:21:41
In reply to New drugs that just don't cut it, posted by Conundrum on October 5, 2010, at 11:15:29
I guess for some and probably many the drugs do work. I just don't feel anything but benzos have worked for me. But then that is me and my small but whole family was on a benzo or is to some degree. Not my grown children though so the problem is probably on my side of the gene pool so to speak. Phillipa
Posted by SLS on October 5, 2010, at 14:34:31
In reply to New drugs that just don't cut it, posted by Conundrum on October 5, 2010, at 11:15:29
> I've been having trouble with new drugs that just don't work or stop working.
>
> The ones that stopped working include:
> pristiq, remeron, abilify, and lamotrigine.
>
> Ritalin can pull me out of a bad mood, but doesn't help with anhedonia, or motivation, surprisingly
>
> The ones that did nothing were lexapro, budeprion SR.
>
> The only thing that partially works consistently is low dose prozac, which helps with motivation and somewhat with enjoyment.
>
> Maybe I should try to augment that.
>
> Maybe I should just go for an MAOI.
>
> I'm also considering tianeptine, which is an indirect 5-HT antagonist, but it sounds like it is weak and mainly for anxiety.
>
> My grandmother tried a bunch of TCA and none worked. She tried Parnate and it worked. Stopped for some reason and went on Nardil and that worked as well.There is a tendency for people with affective disorders to respond to the same treatment as family members do. I guess that leaves some justification to try Parnate, perhaps in combination with Lamictal and/or Abilify.
Good luck. I know you have a lot to think about.
- Scott
Posted by weatherfreak on October 5, 2010, at 23:47:43
In reply to New drugs that just don't cut it, posted by Conundrum on October 5, 2010, at 11:15:29
I personally found mirtazapine probably one of the worst meds ever, I'd put it right up there with Zyprexa.
I also found lamictal totally useless, I think I titrated up to around 200mg whilst on edronax and it did nothing, not a thing!
This is the end of the thread.
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