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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by ihatedrugs on July 27, 2009, at 22:52:20
Hi folks,
I have been taking Savella for about 8 weeks and don't know what to do. It has definitely diminished the sadness but now I'm angry all the time. I hate it. I lose my temper so quickly and seem to be even be bothered by the sound of my husband's voice to the point that I have to tell him to stop talking.
Also, my blood pressure which has never ever been on the high side was 138 over 87 which is super high for me. I do have a lot more energy but at what cost? I start school in 3 weeks and need to decide if I want to go on Emsam or continue with this med and see if this bad mood from eternal hell subsides. What do you guys think is going on? I really need help. Can't keep on yelling all day.
ihatedrugs
Posted by Sigismund on July 27, 2009, at 23:42:20
In reply to Should I stop Savella-?, posted by ihatedrugs on July 27, 2009, at 22:52:20
>It has definitely diminished the sadness but now I'm angry all the time.
How shall we treat this side effect? pot?
What about reducing the dose?
Any idea whether that would help or be worth it?
Posted by Phillipa on July 28, 2009, at 0:11:52
In reply to Should I stop Savella-?, posted by ihatedrugs on July 27, 2009, at 22:52:20
This anger quick without thinking what are you angry about. That's maybe the answer new stadegy. May sound silly maybe not??? Love Phillipa
Posted by floatingbridge on July 28, 2009, at 12:48:18
In reply to Should I stop Savella-?, posted by ihatedrugs on July 27, 2009, at 22:52:20
Hi Ihatedrugs,
Two things come to mind. Are you in therapy? (Sometimes anger may be appropriate, esp. after a depression....two cents worth here.) (Maybe you can ad something to take the edge off your irritability--unless the irritability is truly drug-induced.)
Do you or you pdoc think you'd be stable by school if you switched?
As I recall, you haven't been pleased by the savella--is that true?
I'll look for your posts,
fb
Posted by ihatedrugs on July 28, 2009, at 22:34:40
In reply to Re: Should I stop Savella-? » ihatedrugs, posted by floatingbridge on July 28, 2009, at 12:48:18
> Hi Ihatedrugs,
>
> Two things come to mind. Are you in therapy? (Sometimes anger may be appropriate, esp. after a depression....two cents worth here.) (Maybe you can ad something to take the edge off your irritability--unless the irritability is truly drug-induced.)
>
> Do you or you pdoc think you'd be stable by school if you switched?
>
> As I recall, you haven't been pleased by the savella--is that true?
>
> I'll look for your posts,
>
> fbI've tried therapy but it really isn't for me. The irritability is most likely a side effect of the norepinephrine. Today I actually had a decent day so let's hope it continues. I just have to help manage the irritability better, like recognize it before it gets full blown. I'm going to stick with Savella for another week and if I see diminished irritability, then I may stick with it. I guess part of me is so disappointed by
the unfairness of these meds. They give you some of your mental functioning back but on the flip side you have to deal with all the weight gain, sexual side effects, insomnia, brain zaps, irritability, and all the other crazy se and you wonder is it worth it. But then you think of the beast looming and you know you have no choice. If I could only get rid of the excess weight I have put on since starting meds, I think that would make me feel so much better but no matter what I do nothing works. I hate being fat as much as I hate depression.ihatedrugs
Posted by jrbecker76 on July 29, 2009, at 2:05:02
In reply to Re: Should I stop Savella-?fb, posted by ihatedrugs on July 28, 2009, at 22:34:40
> > Hi Ihatedrugs,
> >
> > Two things come to mind. Are you in therapy? (Sometimes anger may be appropriate, esp. after a depression....two cents worth here.) (Maybe you can ad something to take the edge off your irritability--unless the irritability is truly drug-induced.)
> >
> > Do you or you pdoc think you'd be stable by school if you switched?
> >
> > As I recall, you haven't been pleased by the savella--is that true?
> >
> > I'll look for your posts,
> >
> > fb
>
> I've tried therapy but it really isn't for me. The irritability is most likely a side effect of the norepinephrine. Today I actually had a decent day so let's hope it continues. I just have to help manage the irritability better, like recognize it before it gets full blown. I'm going to stick with Savella for another week and if I see diminished irritability, then I may stick with it. I guess part of me is so disappointed by
> the unfairness of these meds. They give you some of your mental functioning back but on the flip side you have to deal with all the weight gain, sexual side effects, insomnia, brain zaps, irritability, and all the other crazy se and you wonder is it worth it. But then you think of the beast looming and you know you have no choice. If I could only get rid of the excess weight I have put on since starting meds, I think that would make me feel so much better but no matter what I do nothing works. I hate being fat as much as I hate depression.
>What dose are you on? I would try lowering the dose. For the past two weeks, I have been trying out 12.5 mg (I am med sensitive). I noticed the irritability from the first week has since drastically dissipated.
Posted by ihatedrugs on July 31, 2009, at 0:46:08
In reply to Re: Should I stop Savella-?fb » ihatedrugs, posted by jrbecker76 on July 29, 2009, at 2:05:02
> > > Hi Ihatedrugs,
> > >
> > > Two things come to mind. Are you in therapy? (Sometimes anger may be appropriate, esp. after a depression....two cents worth here.) (Maybe you can ad something to take the edge off your irritability--unless the irritability is truly drug-induced.)
> > >
> > > Do you or you pdoc think you'd be stable by school if you switched?
> > >
> > > As I recall, you haven't been pleased by the savella--is that true?
> > >
> > > I'll look for your posts,
> > >
> > > fb
> >
> > I've tried therapy but it really isn't for me. The irritability is most likely a side effect of the norepinephrine. Today I actually had a decent day so let's hope it continues. I just have to help manage the irritability better, like recognize it before it gets full blown. I'm going to stick with Savella for another week and if I see diminished irritability, then I may stick with it. I guess part of me is so disappointed by
> > the unfairness of these meds. They give you some of your mental functioning back but on the flip side you have to deal with all the weight gain, sexual side effects, insomnia, brain zaps, irritability, and all the other crazy se and you wonder is it worth it. But then you think of the beast looming and you know you have no choice. If I could only get rid of the excess weight I have put on since starting meds, I think that would make me feel so much better but no matter what I do nothing works. I hate being fat as much as I hate depression.
> >
>
> What dose are you on? I would try lowering the dose. For the past two weeks, I have been trying out 12.5 mg (I am med sensitive). I noticed the irritability from the first week has since drastically dissipated.
>
>
>
I'm taking 100 mg. I started with the sample packets which has you titrate up to 1oo mg divided in two doses. I have thought of lowering it. However, the irritability seems to be stabilizing for now. So for now I'm going to wait until I see my pdoc and decided what to do.Are you taking Savella for depression or fibro? I take it for depression. Keep me posted on how you are doing so we can compare notes. There aren't many people taking this med for major depression.
Posted by Phillipa on July 31, 2009, at 20:18:02
In reply to Re: Should I stop Savella-?jrbecker, posted by ihatedrugs on July 31, 2009, at 0:46:08
Ihateddrugs you seriously need to turn on your babblemail. JR Becker is a scientist seriously try google. Website. Write me. Phillipa
Posted by ihatedrugs on August 3, 2009, at 13:02:48
In reply to Re: Should I stop Savella-?jrbecker » ihatedrugs, posted by Phillipa on July 31, 2009, at 20:18:02
I don't know what you mean turn on babble mail.
Posted by Phillipa on August 3, 2009, at 13:30:49
In reply to Re: Should I stop Savella-?jphillipa, posted by ihatedrugs on August 3, 2009, at 13:02:48
If you turn on babblemail like an e-mail on this site your posting name will be blue you click on the blue of any posters name and a screen appears and you can write them a message private like e-mail. Try clicking my name and send me one . But to turn yours on go to registration and click activate babblemail then yours will be blue as well and others can send you messages. Oh and kath on social posted to you. See if babblemail was on I or someone else could have let you know in private. Love Phillipa ps to send it the babblemail click send under the screen to type the message. And at the top you can also send yourself a copy hope this is clear????
Posted by TriedEveryDrug on August 3, 2009, at 18:23:50
In reply to Should I stop Savella-?, posted by ihatedrugs on July 27, 2009, at 22:52:20
> Hi folks,
>
> I have been taking Savella for about 8 weeks and don't know what to do. It has definitely diminished the sadness but now I'm angry all the time. I hate it. I lose my temper so quickly and seem to be even be bothered by the sound of my husband's voice to the point that I have to tell him to stop talking.
> Also, my blood pressure which has never ever been on the high side was 138 over 87 which is super high for me. I do have a lot more energy but at what cost? I start school in 3 weeks and need to decide if I want to go on Emsam or continue with this med and see if this bad mood from eternal hell subsides. What do you guys think is going on? I really need help. Can't keep on yelling all day.
> ihatedrugsthe anger/irritability sound like norepinephrine talking.
I had this reaction to desipramine. It lessened a bit after 3 months but never really went away.
I couldn't stand it.
Posted by ihatedrugs on August 4, 2009, at 0:06:00
In reply to Re: Should I stop Savella-? » ihatedrugs, posted by TriedEveryDrug on August 3, 2009, at 18:23:50
> > Hi folks,
> >
> > I have been taking Savella for about 8 weeks and don't know what to do. It has definitely diminished the sadness but now I'm angry all the time. I hate it. I lose my temper so quickly and seem to be even be bothered by the sound of my husband's voice to the point that I have to tell him to stop talking.
> > Also, my blood pressure which has never ever been on the high side was 138 over 87 which is super high for me. I do have a lot more energy but at what cost? I start school in 3 weeks and need to decide if I want to go on Emsam or continue with this med and see if this bad mood from eternal hell subsides. What do you guys think is going on? I really need help. Can't keep on yelling all day.
> > ihatedrugs
>
> the anger/irritability sound like norepinephrine talking.
>
> I had this reaction to desipramine. It lessened a bit after 3 months but never really went away.
>
> I couldn't stand it.It's horrible. Sometimes I didn't know which was worst the depression or irritability. I went to the dr today and we are going to try Emsam. I really hope this one works. I am running out of options.
Thanks for your post
ihatedrugs
Posted by floatingbridge on August 4, 2009, at 11:07:56
In reply to Should I stop Savella-?, posted by ihatedrugs on July 27, 2009, at 22:52:20
I'm sorry the savella was such a bust. I hope emsam is the ticket for you, I really do. Please keep us posted on your progress--I'll look for your posts.
fb
Posted by elanor roosevelt on August 9, 2009, at 15:34:52
In reply to Re: Should I stop Savella-?jrbecker, posted by ihatedrugs on July 31, 2009, at 0:46:08
I have had this reaction with several meds and never succeeded in solving the matter until i stopped the med in question
each time i waited too long and suffered terribly trying to rein in my temper and being disgusted with myself when i didn't
the stress level you are dealing with is not healthy
this reaction is about brain chemistry
therapy won't make it go away
and to deal with the beginning of a school term--yikes
good luck to you whatever you choose to do
Posted by jrbecker76 on August 10, 2009, at 10:41:08
In reply to Re: Should I stop Savella » TriedEveryDrug, posted by ihatedrugs on August 4, 2009, at 0:06:00
> > > Hi folks,
> > >
> > > I have been taking Savella for about 8 weeks and don't know what to do. It has definitely diminished the sadness but now I'm angry all the time. I hate it. I lose my temper so quickly and seem to be even be bothered by the sound of my husband's voice to the point that I have to tell him to stop talking.
> > > Also, my blood pressure which has never ever been on the high side was 138 over 87 which is super high for me. I do have a lot more energy but at what cost? I start school in 3 weeks and need to decide if I want to go on Emsam or continue with this med and see if this bad mood from eternal hell subsides. What do you guys think is going on? I really need help. Can't keep on yelling all day.
> > > ihatedrugs
> >
> > the anger/irritability sound like norepinephrine talking.
> >
> > I had this reaction to desipramine. It lessened a bit after 3 months but never really went away.
> >
> > I couldn't stand it.
>
> It's horrible. Sometimes I didn't know which was worst the depression or irritability. I went to the dr today and we are going to try Emsam. I really hope this one works. I am running out of options.
>
> Thanks for your post
> ihatedrugsJust thought I'd also chime in and say that my 3-week trial of Savella is now over as well and feeling much better back on Cymbalta. I tried a low dose (12.5mg) of Savella on the urging of my pdoc who thought I would respond well considering that I have always done better on the SNRIs vs SSRIs. However, I was skeptical from the beginning given all the poor feedback posted online about Milnacipran over the years. It actually wasn't the irritability in the end that made me stop it (this side effect actually dissipated). However, my mood was still highly labile. I was overly-sensitive to even minor issues. The noradrenergic side of the drug is probably to blame, as I have had somewhat similar reactions to Reboxetine and Seroquel. On the plus side, my physical energy had improved and it had no sexual side effects at all (in fact, it might have helped in that dept).
JB
Posted by ihatedrugs on August 14, 2009, at 4:03:47
In reply to Re: Should I stop Savella - i did, posted by jrbecker76 on August 10, 2009, at 10:41:08
> > > > Hi folks,
> > > >
> > > > I have been taking Savella for about 8 weeks and don't know what to do. It has definitely diminished the sadness but now I'm angry all the time. I hate it. I lose my temper so quickly and seem to be even be bothered by the sound of my husband's voice to the point that I have to tell him to stop talking.
> > > > Also, my blood pressure which has never ever been on the high side was 138 over 87 which is super high for me. I do have a lot more energy but at what cost? I start school in 3 weeks and need to decide if I want to go on Emsam or continue with this med and see if this bad mood from eternal hell subsides. What do you guys think is going on? I really need help. Can't keep on yelling all day.
> > > > ihatedrugs
> > >
> > > the anger/irritability sound like norepinephrine talking.
> > >
> > > I had this reaction to desipramine. It lessened a bit after 3 months but never really went away.
> > >
> > > I couldn't stand it.
> >
> > It's horrible. Sometimes I didn't know which was worst the depression or irritability. I went to the dr today and we are going to try Emsam. I really hope this one works. I am running out of options.
> >
> > Thanks for your post
> > ihatedrugs
>
> Just thought I'd also chime in and say that my 3-week trial of Savella is now over as well and feeling much better back on Cymbalta. I tried a low dose (12.5mg) of Savella on the urging of my pdoc who thought I would respond well considering that I have always done better on the SNRIs vs SSRIs. However, I was skeptical from the beginning given all the poor feedback posted online about Milnacipran over the years. It actually wasn't the irritability in the end that made me stop it (this side effect actually dissipated). However, my mood was still highly labile. I was overly-sensitive to even minor issues. The noradrenergic side of the drug is probably to blame, as I have had somewhat similar reactions to Reboxetine and Seroquel. On the plus side, my physical energy had improved and it had no sexual side effects at all (in fact, it might have helped in that dept).
>
>
> JB
>Thanks for your response. I stopped taking Savella two weeks ago. Didn't have to deal with withdrawal issues thank goodness. I actually never did very well on snri's, they worked somewhat for depression but made me kind of reclusive. I'm usually pretty social. I would also say that my moods were at times all over the place. Nonetheless, glad to be off of it.
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