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Re: Should I stop Savella - i did

Posted by jrbecker76 on August 10, 2009, at 10:41:08

In reply to Re: Should I stop Savella » TriedEveryDrug, posted by ihatedrugs on August 4, 2009, at 0:06:00

> > > Hi folks,
> > >
> > > I have been taking Savella for about 8 weeks and don't know what to do. It has definitely diminished the sadness but now I'm angry all the time. I hate it. I lose my temper so quickly and seem to be even be bothered by the sound of my husband's voice to the point that I have to tell him to stop talking.
> > > Also, my blood pressure which has never ever been on the high side was 138 over 87 which is super high for me. I do have a lot more energy but at what cost? I start school in 3 weeks and need to decide if I want to go on Emsam or continue with this med and see if this bad mood from eternal hell subsides. What do you guys think is going on? I really need help. Can't keep on yelling all day.
> > > ihatedrugs
> >
> > the anger/irritability sound like norepinephrine talking.
> >
> > I had this reaction to desipramine. It lessened a bit after 3 months but never really went away.
> >
> > I couldn't stand it.
>
> It's horrible. Sometimes I didn't know which was worst the depression or irritability. I went to the dr today and we are going to try Emsam. I really hope this one works. I am running out of options.
>
> Thanks for your post
> ihatedrugs

Just thought I'd also chime in and say that my 3-week trial of Savella is now over as well and feeling much better back on Cymbalta. I tried a low dose (12.5mg) of Savella on the urging of my pdoc who thought I would respond well considering that I have always done better on the SNRIs vs SSRIs. However, I was skeptical from the beginning given all the poor feedback posted online about Milnacipran over the years. It actually wasn't the irritability in the end that made me stop it (this side effect actually dissipated). However, my mood was still highly labile. I was overly-sensitive to even minor issues. The noradrenergic side of the drug is probably to blame, as I have had somewhat similar reactions to Reboxetine and Seroquel. On the plus side, my physical energy had improved and it had no sexual side effects at all (in fact, it might have helped in that dept).


JB


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URL: http://www.dr-bob.org/babble/20090810/msgs/911300.html