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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by michael45 on March 28, 2009, at 15:39:24
for anxiety + depression..tried many others and nothing helped
what is your guys opinion on nardil?
Posted by myco on March 28, 2009, at 16:21:22
In reply to heard nardil was good..any other opinions on it?, posted by michael45 on March 28, 2009, at 15:39:24
Have you tried MAOI's before? There are many people on here who have experience with Nardil...correct board to seek advice for sure.
> for anxiety + depression..tried many others and nothing helped
>
> what is your guys opinion on nardil?
Posted by jedi on March 28, 2009, at 19:49:27
In reply to heard nardil was good..any other opinions on it?, posted by michael45 on March 28, 2009, at 15:39:24
> for anxiety + depression..tried many others and nothing helped
>
> what is your guys opinion on nardil?Hi,
If your depression is atypical then Nardil can work when no other ADs have. Signs of atypical depression are:
A. Mood reactivity (i.e., mood brightens in response to actual or potential positive events)
B. At least two of the following:
1. Significant weight gain or increase in appetite ("comfort eating")
2. Hypersomnia (sleeping too much, as opposed to the insomnia present in melancholic depression)
3. Leaden paralysis (i.e., heavy, leaden feelings in arms or legs)
4. Long-standing pattern of interpersonal rejection sensitivity (not limited to episodes of mood disturbance) that results in significant social or occupational impairment.The MAOIs are worth a try if all of the others fail. I believe they should be 2nd tier medications, after SSRIs, for atypical depression.
Godd Luck,
Jedi
Posted by michael45 on March 29, 2009, at 7:06:07
In reply to Re: heard nardil was good..any other opinions on it?, posted by jedi on March 28, 2009, at 19:49:27
hello jedi
yeah i do have about 2 of those atypical symptoms.
if sleeping 12 hours a day counts as Hypersomnia?
and i havent talked to anyone besides my family in 3 weeks or really left my house, i feel so anxious and feel almost socially phobic..but not severe i guess you could say . dpes that counts as Long-standing pattern of interpersonal rejection sensitivity?
Posted by bleauberry on March 29, 2009, at 9:02:42
In reply to heard nardil was good..any other opinions on it?, posted by michael45 on March 28, 2009, at 15:39:24
Nardil and Parnate and Clomipramine were, and still are, the kings of the antidepressant world. In 50 years, there still has not been any drug invented that outperforms them.
If you haven't already, another option is to combine serotonin and norepinephrine meds, for example, Zoloft + Nortriptyline. The hype of Cymbalta and Effexor accomplishing that is, well, hype. They have such small action on norepinephrine compared to serotonin. You want a balanced effect on both, which can only be achieved with an MAOI or with two different meds.
Posted by myco on March 29, 2009, at 14:29:07
In reply to Re: heard nardil was good..any other opinions on it?, posted by bleauberry on March 29, 2009, at 9:02:42
Bleauberry,
Is zoloft/nortrip a combo that is proposed regularly for anxiety disorders like SAD/GAD or would that lend to increased anxiety do you think?
myco
-------------
> Nardil and Parnate and Clomipramine were, and still are, the kings of the antidepressant world. In 50 years, there still has not been any drug invented that outperforms them.
>
> If you haven't already, another option is to combine serotonin and norepinephrine meds, for example, Zoloft + Nortriptyline. The hype of Cymbalta and Effexor accomplishing that is, well, hype. They have such small action on norepinephrine compared to serotonin. You want a balanced effect on both, which can only be achieved with an MAOI or with two different meds.
Posted by jedi on March 29, 2009, at 23:21:53
In reply to Re: heard nardil was good..any other opinions on it? » jedi, posted by michael45 on March 29, 2009, at 7:06:07
> hello jedi
>
> yeah i do have about 2 of those atypical symptoms.
>
> if sleeping 12 hours a day counts as Hypersomnia?
>
> and i havent talked to anyone besides my family in 3 weeks or really left my house, i feel so anxious and feel almost socially phobic..but not severe i guess you could say . dpes that counts as Long-standing pattern of interpersonal rejection sensitivity?
>Hi again,
I would say, given your symptoms, that Nardil would be worth a trial. I wouldn't say that three weeks was long term rejection sensitivity, but if you think back it has probably been longer than that. I am over 50 and my social anxiety with rejection sensitivity started in my early teen years. I really wish I would have been treated for it back then, since longstanding social anxiety can affect all aspects of a persons life.And sleeping 12 hours daily would count as hypersomnia. In the past, I would sleep just to escape the pain of the depression. Pretty hard to be productive, when you are sleeping away your life.
Good luck in your pursuit of wellness,
Jedi
This is the end of the thread.
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