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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Sheilac on August 28, 2007, at 8:49:52
Since I have fried my serotonin receptors in my bladder, I am trying to find drugs that effect the neuroepinephrine. What drugs? ADD drugs?
I can take Wellbutrin (dopanine) but it does make me cranky and mean.
Posted by sam123 on August 28, 2007, at 10:35:59
In reply to Drugs that effect Neuroepinephrine?, posted by Sheilac on August 28, 2007, at 8:49:52
Effexor
Welbrutrin
Cymbalta
Staterra
MAOI's
Amphetamines
some non-amphetamine stims (Ritalin)
Most TCA's
Posted by SometimesBlue on August 28, 2007, at 12:41:01
In reply to Drugs that effect Neuroepinephrine?, posted by Sheilac on August 28, 2007, at 8:49:52
> Since I have fried my serotonin receptors in my bladder,
What would do this? And is it possible to "fry" them in your brain?
-Blue
Posted by Racer on August 28, 2007, at 13:01:12
In reply to Drugs that effect Neuroepinephrine?, posted by Sheilac on August 28, 2007, at 8:49:52
> Since I have fried my serotonin receptors in my bladder, I am trying to find drugs that effect the neuroepinephrine.
How did you come to the conclusion that your serotonin receptors were "fried" in your bladder? It looks as though urologists are actually using SRI type drugs to treat a lot of bladder symptoms, so I'm not sure avoiding them will help.
More to the point, though, just targeting another neurotransmitter isn't necessarily going to be the answer for you. If serotinergic drugs help with your mood disorder, then switching to a drug targeting norepinephrine won't necessarily be effective for you. No one really knows yet what causes mood disorders, and no one really knows how drugs treat mood disorders. More is being learned every day, of course, but right now we're still basically groping along in very dim light.
>
> I can take Wellbutrin (dopanine) but it does make me cranky and mean.Wellbutrin targets norepinephrine, as well as dopamine -- in fact, they're both part of the same system. Dopamine is a precursor to norepinephrine, as well as being a neurotransmitter in its own right.
But for practical purposes, if Wellbutrin makes you cranky and mean, it's likely other noradrenergic drugs will do the same.
Good luck.
Posted by Sheilac on August 28, 2007, at 15:32:08
In reply to Re: Drugs that effect norepinephrine? » Sheilac, posted by Racer on August 28, 2007, at 13:01:12
I've been to several urologists and for some reason my bladder becomes inflammed whenever I take any of the SSRI/SNRI drugs. Wellbutrin doesn't cause any inflamation. We're not sure why I am having this reaction. Although, I have been taking these drugs since 1990 - so I don't know if there are any longterm studies done on bladder reactions to SSRIs.
The reason why I asked about norepinephrine is beacuse I noticed a few years ago when I took Phentermine (a diet pill) that I felt great, no depression, more focus and motivation. I research what brain chemicals are effected by Phentermine and it said norepinephrine, dopamine and adrenaline. Plus, no bladder reactions.
Since I don't want to take diet pills the rest of my life, I figured I would look into what other drugs target these same chemicals.
Posted by Phillipa on August 28, 2007, at 19:28:37
In reply to Re: Drugs that effect norepinephrine?, posted by Sheilac on August 28, 2007, at 15:32:08
After a while they will the diet pills make you very hyper at least that is what happened to me in the 60's it wasn't a crime then to use diet pills although I only weighted ll8 My OB-GYN gave me a months supply don't recall the name but only took them every other day and energy was incredible and this was way before I ever had any panic anxiety or what not. At the time I was normal. Phillip
Posted by tecknohed on August 28, 2007, at 20:56:29
In reply to Drugs that effect Neuroepinephrine?, posted by Sheilac on August 28, 2007, at 8:49:52
How about other serotonergic meds without a re-uptake inhibiting mechanism?
Remeron/Zispin (mirtazepine)
Buspar (buspirone)
Desyrel (trazodone)
There are others.Would these still cause you bladder problems? Would they not be worth considering?
Posted by Optimist on August 28, 2007, at 22:34:17
In reply to Re: Drugs that effect Neuroepinephrine? » Sheilac, posted by tecknohed on August 28, 2007, at 20:56:29
Increasing your estrogen is best way to naturally increase your norepinephrine levels. Consider talking to your doctor about possibly estrogen treatment.
Posted by Phillipa on August 28, 2007, at 23:22:32
In reply to Re: Drugs that effect Neuroepinephrine?, posted by Optimist on August 28, 2007, at 22:34:17
Really? Maybe that's why a lot of women perimenopause or post menapausal get depressed? Gotta google that one thanks Phillipa
Posted by Optimist on August 29, 2007, at 9:09:34
In reply to Re: Drugs that effect Neuroepinephrine? » Optimist, posted by Phillipa on August 28, 2007, at 23:22:32
> Really? Maybe that's why a lot of women perimenopause or post menapausal get depressed? Gotta google that one thanks Phillipa
Very true. There's a lot of information on the internet about this phenomenon.
Brian
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