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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by linkadge on August 31, 2006, at 16:25:41
I read this from an article, read the whole article for context. Its about mice lacking MAO-A, or MAO-B.
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http://www.eurekalert.org/pub_releases/2004-09/asfb-smp090704.php
"Looking further into the matter, Dr. Shih determined that a spontaneous mutation in a single nucleic acid base pair in the MAO A gene created a premature stop which prevented it from being made into a protein. The scientists hypothesize that the mutation was due to elevated levels of the MAO B substrate phenylethylamine in the MAO B knockout mice. Phenylethylamine is a neuromodulator which, when broken down into its metabolites, has been shown to cause mutations in DNA. "
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Does this mean that elevating PEA with a MAO-B inhibitor could be neurotoxic ?Linkadge
Posted by willyee on August 31, 2006, at 20:50:43
In reply to Metabolite of PEA toxic to DNA?, posted by linkadge on August 31, 2006, at 16:25:41
With numerous statings otherwise,a sugggestion that Maoi elevation results could cause toxcity would at least deserve the respect of a few more studies,even two,is there anything else you came across,is this the only thing or is there more,i dont take value in anything articles any more honestly seems u find contradticory articles every where you turn.If you try to live off them your head will spin.
This is the end of the thread.
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