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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by sadaiy on September 6, 2005, at 14:10:53
Ok, I understand that certain people build up a tolerance to certain drugs... But lets say i have built up some tolerance to something, if i stop taking that drug for 6 months or a year, does my tolerance go away ?
Posted by Bill LL on September 6, 2005, at 14:15:11
In reply to tolerance, posted by sadaiy on September 6, 2005, at 14:10:53
A lot of times it does go away. For some of the sleep drugs, just stopping them for a couple of weeks can lower the tolerance.
> Ok, I understand that certain people build up a tolerance to certain drugs... But lets say i have built up some tolerance to something, if i stop taking that drug for 6 months or a year, does my tolerance go away ?
Posted by Ilene on September 6, 2005, at 19:10:02
In reply to tolerance, posted by sadaiy on September 6, 2005, at 14:10:53
I've suffered from "Prozac poop-out" and it didn't work for me the 2nd time around. A combo of Prozac and Wellbutrin is working some, however.
I.
Posted by Phillipa on September 6, 2005, at 21:09:03
In reply to Re: tolerance » sadaiy, posted by Ilene on September 6, 2005, at 19:10:02
For a lot of people a second trial of an AD doesn't work. Fondly, Phillipa
Posted by sadaiy on September 7, 2005, at 13:33:34
In reply to Re: tolerance, posted by Phillipa on September 6, 2005, at 21:09:03
> For a lot of people a second trial of an AD doesn't work. Fondly, Phillipa
Does the tolerance for "benzo's" go away ?
Also what about for sleeping medications,
Has anyone had Remeron or trazadome "poop out" on them, but go back to it later for sleep ?
Another thing I was thinking is that if you build up a tolerance to a specific Benzo, lets say "Clonizapam" [i think that is the spelling] do you also build up tolerence to every other benzo ?
Posted by Mr.Scott on September 8, 2005, at 13:49:04
In reply to Re: tolerance, posted by sadaiy on September 7, 2005, at 13:33:34
Tolerance to CNS depressants like clonazepam indicates a tolerance for other like compounds especially other benzos (Ativan, valium, etc)and to some extent barbiturates, and alcohol. Generally speaking the tolerance will go away upon discontinuation, although it may recur quicker the next time you take it. Tolerance is also variable for different effects of the same drug even in the same person.With stimulants, the same principles apply except that sensitization may also occur. This is where an individual has an enhanced response over time to the same dose. Usually only for the side effects however. Basically...The good part dissipates and bad part becomes more pronounced.
I don't have a very good understanding of antidepressant poop-out except to know it sucks.
The body tries to reach homeostasis or its original set points. The brain seems particularly aggressive in trying to get back to its original state even if that state was depression or anxiety.
Scott
Posted by phillipa on September 8, 2005, at 21:51:26
In reply to Re: tolerance » sadaiy, posted by Mr.Scott on September 8, 2005, at 13:49:04
Oh Great! So what's the answer? Fondly, Phillipa
Posted by sadaiy on September 8, 2005, at 22:22:23
In reply to Re: tolerance » sadaiy, posted by Mr.Scott on September 8, 2005, at 13:49:04
>
> Tolerance to CNS depressants like clonazepam indicates a tolerance for other like compounds especially other benzos (Ativan, valium, etc)and to some extent barbiturates, and alcohol. Generally speaking the tolerance will go away upon discontinuation, although it may recur quicker the next time you take it. Tolerance is also variable for different effects of the same drug even in the same person.
>
> With stimulants, the same principles apply except that sensitization may also occur. This is where an individual has an enhanced response over time to the same dose. Usually only for the side effects however. Basically...The good part dissipates and bad part becomes more pronounced.
>
> I don't have a very good understanding of antidepressant poop-out except to know it sucks.
>
> The body tries to reach homeostasis or its original set points. The brain seems particularly aggressive in trying to get back to its original state even if that state was depression or anxiety.
>
> ScottOk, if the brain "aggressively tries to reach "homeostasis"", then why are people stuck taking things for sleep ?
If I am taking Remeron 15mg, + 30mg Restoril now, will I ever in the future again be able to sleep medication free ?
Posted by Mr.Scott on September 8, 2005, at 22:32:50
In reply to Re: tolerance, posted by sadaiy on September 8, 2005, at 22:22:23
IMO...
Most people on long-term sleep meds (benzos) take them to allay rebound/withdrawal so they can get to sleep. After a few months many experts believe they induce little if any sleep promoting effect.
Scott
This is the end of the thread.
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