Posted by Mr.Scott on September 8, 2005, at 13:49:04
In reply to Re: tolerance, posted by sadaiy on September 7, 2005, at 13:33:34
Tolerance to CNS depressants like clonazepam indicates a tolerance for other like compounds especially other benzos (Ativan, valium, etc)and to some extent barbiturates, and alcohol. Generally speaking the tolerance will go away upon discontinuation, although it may recur quicker the next time you take it. Tolerance is also variable for different effects of the same drug even in the same person.
With stimulants, the same principles apply except that sensitization may also occur. This is where an individual has an enhanced response over time to the same dose. Usually only for the side effects however. Basically...The good part dissipates and bad part becomes more pronounced.
I don't have a very good understanding of antidepressant poop-out except to know it sucks.
The body tries to reach homeostasis or its original set points. The brain seems particularly aggressive in trying to get back to its original state even if that state was depression or anxiety.